Wyniki wyszukiwania

1

The influence of arginine vasopressin (AVP) on phagocytosis in the unicellular Tetrahymena

100%

Jahn I., Csaba G.

Acta Protozoologica

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1987

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tom 26

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nr 1

2

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Influence of hydration state on hormonal responses to exercise in dogs

86%

Baker M. A., Doris P. A., Turlejska E.

Journal of Physiology and Pharmacology

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1991

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tom 42

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nr 3

The purpose of these studies was to determine how plasma levels of arginine vasopressin (pAVP) are related to workload, plasma osmolality (pOsm), blood volume (BV) and plasma angiotensin II (pAII) in exercising dogs. Measurements were made in dogs running on a treadmill at 7.5 km. hr⁻¹ at slopes of 0, 10% and 20% when they were hydrated ad lib and when they had been deprived of drinking water and also in dogs running on a 20% slope after an IV infusion of hypertonic NaCl. Dehydration increased pOsm by 6.6% and reduced BV by 10% in resting dogs. In dehydrated animals, pAVP, pAII and pOsm were elevated above hydrated levels at rest and during exercise at all three workloads. In hydrated dogs, pOsm rose during exercise at 10% and 20% slopes but pAVP rose above resting levels only at the highest workload and pAII was not affected by exercise. In dehydrated dogs, pOsm and pAVP rose during exercise at 10% and 20% slopes and pAII was elevated at the 20% slope. BV decreased during exercise at the highest workload in both hydrated and dehydrated animals. After hypertonic NaCl, pAVP rose during exercise but pOsm and pAII did not. The results suggest that both osmotic and nonosmotic factors contribute to the release of AVP in exercising dogs and that exercise leads to a leftward shift in the relationship of pAVP to pOSM which could be a result of reduced blood volume.

3

Effect of ANP on the RNA content in hypothalamic NSO and NPV cells in rats

86%

Siekierska E., Czechowicz K., Zabczyk I.

Zoologica Poloniae

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1996

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tom 41

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nr 1-4

4

Effect of NG-nitro-L-arginine on pressor action of arginine vasopressin in normotensive [WKY] and spontaneously hypertensive [SHR] rats

86%

Stys T., Szczepanska-Sadowska E.

Journal of Physiology and Pharmacology

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1994

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tom 45

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nr 2

5

Traumatic brain injury results in a concomitant increase in neocortical expression of vasopressin and its V1A receptor

72%

Pascale C. L., Szmydynger-Chodobska J., Sarri J. E., Chodobski A.

Journal of Physiology and Pharmacology. Supplement

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2006

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tom 57

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nr 11

161-167

Arginine vasopressin (AVP) has been shown to promote the disruption of the blood-brain barrier (BBB) and the formation of edema in various animal models of brain injury. However, the source(s) of this AVP have not been identified. Since the cerebral cortex was considerably affected in some of these brain injury models, we sought to determine if AVP was produced in the cerebral cortex, and, if so, whether or not this cortical AVP expression was up regulated after injury. In the present study, a controlled cortical impact model of traumatic brain injury (TBI) in rats was used, and the temporal changes in expression of AVP and its V1a receptor were analyzed by real-time reverse-transcriptase polymerase chain reaction. The expression of AVP and its V1a receptor in the ipsilateral cortex adjacent to the lesion area was significantly up regulated between 4 h and 1day post-TBI. The maximum increase in mRNA for AVP (4.3-fold) and its receptor (2.6-fold) in the ipsilateral vs. contralateral cortex was observed at 6 h post-TBI. Compared to sham-injured rats, no statistically significant changes in expression of AVP or its receptor were found in the contralateral cortex. These results suggest that the cerebral cortex is an important source of AVP in the injured brain, and the parallel increase in the expression of AVP and its cognate receptor may act to augment the actions of AVP related to promoting the disruption of the BBB and the formation of post-traumatic edema.

6

Hippocampal vasopressin (AVP) dialysis and the conditioned eyelid reflex in rabbits

72%

Orlowska-Majdak M., Kolodziejski P., Traczyk W. Z.

Journal of Physiology and Pharmacology

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2001

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tom 52

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nr 4,2

The role of arginine vasopressin (AVP) dialyzed into the hippocampus or caudate nucleus as the reference structure in the acquisition and extinction of the conditioned eyelid reflex in rabbit was investigated. Phonopneumatic stimulator was used for the generation of conditioned and unconditioned stimuli, and for control of the recorder. Opto-electronic sensor transduced the behavioral responses. Microdialysis probes were chronically implanted into the brain structures. AVP was dialyzed into the brain structures during the extinction procedure. Restraining of the process of extinction was shown during AVP dialysis through the hippocampus and caudate nucleus but the effect in hippocampus was stronger and longer lasting than in caudate nucleus. The influence of AVP dialyzed through the hippocampus on the course of acquisition was biphasic. Some insignificant improvement of learning was observed at the beginning of training and then compensatory, significant restraining of learning. After AVP dialysis through the caudate nucleus only the late, insignificant tendency to improve learning was shown. The effects of AVP were dose-dependent in inversely proportional manner and long-term in nature, especially the effects in hippocampus.

7

Memory effects of arginine vasopressin [AVP] and [7-9] fragment of its peptide chain in rats

72%

Klimkiewicz T.

Acta Neurobiologiae Experimentalis

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2001

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tom 61

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nr 4

8

Muscle damage, hydration, electrolyte balance and vasopressin concentration in successful and exhausted endurance horses

58%

Munoz A., Riber C., Trigo P., Castejon F.

Polish Journal of Veterinary Sciences

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2010

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tom 13

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nr 2

9

Effect of pinealectomy and melatonin on vasopressin-potentiated passive avoidance in rats

58%

Juszczak M., Drobnik J., Guzek J. W., Schwarzberg H.

Journal of Physiology and Pharmacology

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1996

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tom 47

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nr 4

10

The influence of vasopressin or oxytocin on thyroid-stimulating hormone and thyroid hormones' concentrations in blood plasma of euthyroid rats

58%

Ciosek J., Stempniak B.

Journal of Physiology and Pharmacology

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1997

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tom 48

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nr 4

11

Nitric oxide and prostaglandin systems in the stimulation of hypothalamic-pituitary-adrenal axis by neurotransmitters and neurohormones

58%

Bugajski J., Gadek-Michalska A., Bugajski A. J.

Journal of Physiology and Pharmacology

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2004

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tom 55

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nr 4

The review presents our results on the regulatory role of prostaglandins (PG) and nitric oxide (NO) in the activation of hypothalamic-pituitary-adrenal (HPA) axis by cholinergic, adrenergic and histaminergic systems and by neurohormones: corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) under basal conditions. The synthesis of endogenous PG or NO was inhibited by non-selective and selective cyclooxygenase (COX) antagonists and nitric oxide synthase (NOS) blockers given 15 min before the respective receptor agonist and HPA axis activity was assessed 1 h later by measuring plasma ACTH and serum corticosterone levels. The muscarinic agent - carbachol-induced HPA response was considerably supressed by piroxicam, a predominantly constitutive cyclooxygenase (COX-1) inhibitor and significantly diminished by indomethacin, a non-selective COX blocker, but was unaffected by compound NS-398, an inducible cyclooxygenase (COX-2) antagonist. A non-selective NOS antagonist L-NAME and neuronal NOS blocker L-NNA significantly intensified the carbachol-induced corticosterone secretion. The nicotine-induced increase in ACTH and corticosterone response was significantly supressed by piroxicam, and diminished by indomethacin, but was significantly augmented by L-NAME and L-NNA. The inhibition of PG synthesis by indomethacin totally abolished or reversed the increase of nicotine-induced hormone responses to both NOS blockers. The i.c.v. phenylephrine, an alpha1-adrenergic receptor agonist - evoked HPA response was significantly impaired by piroxicam and compound NS-398 and more potently reduced by L-NAME. The i.c.v. clonidine, an alpha2-adrenergic agonist - elicited HPA response was also considerably decreased by piroxicam, compound NS-398 and L-NAME. By contrast, the stimulatory effect of i.c.v. isoprenaline, a non-selective ß-adrenergic agonist, was not altered by either COX or NOS inhibitors. The i.c.v. histamine- and HTMT, a histamine H1-agonist-induced ACTH and corticosterone response were significantly diminished by piroxicam and indomethacin, respectively. Compound NS-398, did not markedly alter the HPA response to HTMT or amthamine, a histamine H2 receptor agonist. Inhibition of endogenous NO synthesis by a neuronal NOS inhibitor 7-nitroindazole markedly enhanced the histamine-induced hormone secretion, abolished the HTMT-induced response and did not substantially alter the amthamine-evoked ACTH and corticosterone secretion. COX blockers did not significantly affect the CRH-induced HPA response and the inhibition of NO synthesis by L-NNA markedly intensified ACTH response. The vasopressin-stimulated increase in HPA response, was considerably reduced by the inhibition of PG synthesis by both COX antagonists while inhibition of NO synthesis by NOS blockers greatly enhanced this response. The involvement of PG and NO in the neurohormonal regulation of HPA activity depends mainly on greatly complex and tightly regulated mechanisms at the level of second messengers IP3 and adenylyl cyclase systems.

Ograniczanie wyników

The influence of arginine vasopressin (AVP) on phagocytosis in the unicellular Tetrahymena

Influence of hydration state on hormonal responses to exercise in dogs

Effect of ANP on the RNA content in hypothalamic NSO and NPV cells in rats

Effect of NG-nitro-L-arginine on pressor action of arginine vasopressin in normotensive [WKY] and spontaneously hypertensive [SHR] rats

Traumatic brain injury results in a concomitant increase in neocortical expression of vasopressin and its V1A receptor

Hippocampal vasopressin (AVP) dialysis and the conditioned eyelid reflex in rabbits

Memory effects of arginine vasopressin [AVP] and [7-9] fragment of its peptide chain in rats

Muscle damage, hydration, electrolyte balance and vasopressin concentration in successful and exhausted endurance horses

Effect of pinealectomy and melatonin on vasopressin-potentiated passive avoidance in rats

The influence of vasopressin or oxytocin on thyroid-stimulating hormone and thyroid hormones' concentrations in blood plasma of euthyroid rats

Nitric oxide and prostaglandin systems in the stimulation of hypothalamic-pituitary-adrenal axis by neurotransmitters and neurohormones