Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: antimutagenic compound

Sortuj według:

Ogranicz wyniki do:

Evaluation of the immunomodulatory activity of four compounds exerting antimutagenic effects on human lymphocytes in vitro

100%

Gasiorowski K., Brokus B., Tabaka H.

Cellular and Molecular Biology Letters

2000

tom 05

nr 4

469-481

Four compounds previously described as antimutagenic for human lymphocytes in vitro were tested on their immunomodulatory activity in lymphocyte cultures. The standard immunocytochemical methods were applied for microscopic examination of the percentual representation of the main lymphocyte subpopulation. The results imply that all of the tested compounds exhibited significant immunomodulatory effect, with that of fluphenazine being the strongest, whereas that of todralazine is the weakest. Two of the tested compounds: anthocyanins from Aronia melanocarpa fruit, and alkylresorcinols from cereal grains, also exhibited a distinct immunomodulatory activity, and it deserves adequate attention as an activity exerted by natural products, commonly present in regular human diet. The analysis of the proliferating cell fraction, and the estimation of the cell proliferation rate suggest that the effect of the tested compounds might depend on an increase in the number of lymphocytes which expressed their differentiation antigens on the cell membranes.

A comparison of the methods applied to detect apoptosis in genotoxically-damaged lymphocytes cultured in the presence of four antimutagens

84%

Gasiorowski K., Brokos B., Kulma A., Ogorzalek A., Skorkowska K.

Cellular and Molecular Biology Letters

2001

tom 06

nr 2

Ograniczanie wyników

2 Cellular and Molecular Biology Letters

2 Gasiorowski K.

1 Brokos B.

1 Brokus B.

1 Kulma A.

1 Ogorzalek A.

1 Skorkowska K.

1 Tabaka H.

1 2001

1 2000

Wyniki wyszukiwania

Evaluation of the immunomodulatory activity of four compounds exerting antimutagenic effects on human lymphocytes in vitro

A comparison of the methods applied to detect apoptosis in genotoxically-damaged lymphocytes cultured in the presence of four antimutagens