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Exploration of anti-plasmodial activity of Prunus cerasoides Buch.-Ham. ex D. Don (family: Rosaceae) and its wood chromatographic fractions

100%

Sachdeva C., Kumar S., Kaushik N. K.

Acta Parasitologica

2021

tom 66

nr 1

Fourier transform infrared spectroscopy as a tool for identification of crude microbial extracts with anti-malarial potential

100%

Sankarganesh P., Joseph B.

Acta Parasitologica

2016

tom 61

nr 1

The in vitro antimalarial interaction of 9-hydroxycalabaxanthone and alpha-mangostin with mefloquine/artesunate

84%

Chaijaroenkul W., Na-Bangchang K.

Acta Parasitologica

2015

tom 60

nr 1

The effects of bistramides on rodent malaria

67%

Gautret P., Le P. P., Biard J. F., Menard D., Verbist J. F., Marjolet M.

Acta Parasitologica

1998

tom 43

nr 1

Bistramide D and K were extracted from a New Caledonian marine colonial ascidian Lissoclinum bistratum and tested against Plasmodium berghei and P. vinckei petteri in mice. Bistramide D was able to reduce parasitaemia by almost 50% in P. berghei infected mice, but the ID₅₀ (>5 mg/kg) was very close to the LD₅₀ (8 mg/kg). In the same assay, bistramide K was less active than bistramide D. The mid-term trophozoite and the old trophozoite were shown to be the stages most sensitive to bistramide D in P. vinckei petteri infected mice. Therefore, bistramides are interesting experimental tools but do not present a major interest as potential antimalarial drugs.

Ograniczanie wyników

4 Acta Parasitologica

1 Biard J. F.

1 Chaijaroenkul W.

1 Gautret P.

1 Joseph B.

1 Kaushik N. K.

1 Kumar S.

1 Le P. P.

1 Marjolet M.

1 Menard D.

1 Na-Bangchang K.

1 Sachdeva C.

1 Sankarganesh P.

1 Verbist J. F.

1 2021

1 2016

1 2015

1 1998

Wyniki wyszukiwania

Exploration of anti-plasmodial activity of Prunus cerasoides Buch.-Ham. ex D. Don (family: Rosaceae) and its wood chromatographic fractions

Fourier transform infrared spectroscopy as a tool for identification of crude microbial extracts with anti-malarial potential

The in vitro antimalarial interaction of 9-hydroxycalabaxanthone and alpha-mangostin with mefloquine/artesunate

The effects of bistramides on rodent malaria