Wyniki wyszukiwania

1

Antibiotic therapy and fat digestion and absorption in cystic fibrosis

100%

Lisowska A., Pogorzelski A., Oracz G., Skorupa W., Cofta S., Szydlowski J., Socha J., Walkowiak J.

Acta Biochimica Polonica

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2011

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tom 58

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nr 3

Antibiotic therapy in the cystic fibrosis (CF) mouse model has been shown to result in reduced bacterial load of the intestine and significant body mass gain. The effect was suggested to be linked to the improvement of intestinal digestion and absorption. Therefore, we aimed to assess the influence of routinely applied antibiotic therapy in CF patients on fat assimilation. Twenty-four CF patients aged 6 to 30 years entered the study. Inclusion criteria comprised confirmed exocrine pancreatic insufficiency and bronchopulmonary exacerbation demanding antibiotic therapy. Exclusion criteria comprised: antibiotic therapy six weeks prior to the test, liver cirrhosis, diabetes mellitus, oxygen dependency, the use of systemic corticosteroids. In all enrolled CF subjects, 13C-labelled mixed triglyceride breath test (13C MTG-BT) was performed to assess lipid digestion and absorption, before and after antibiotic therapy. Sixteen subjects were treated intravenously with ceftazidime and amikacin, eight patients orally with ciprofloxacin. Cumulative percentage dose recovery (CPDR) was considered to reflect digestion and absorption of lipids. The values are expressed as means (medians). The values of CPDR before and after antibiotic therapy did not differ in the whole studied group [4.6(3.3) % vs. 5.7(5.3) %, p = 0.100] as well as in the subgroup receiving them intravenously [4.6(3.2) % vs. 5.7(5.3) %, p = 0.327] or in that with oral drug administration [4.6(3.4) % vs. 5.7(5.4) %, p = 0.167]. In conclusion, antibiotic therapy applied routinely in the course of pulmonary exacerbation in CF patients does not seem to result in an improvement of fat digestion and absorption.

2

Local antibiotic therapy of the respiratory system infections in mechanically ventilated patients

100%

Ciesla A., Bociaga-Jasik M., Mach T., Warunek W.

Acta Biologica Cracoviensia. Series Zoologia

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2007

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tom 49

59-64

3

Immunotherapy in Gram-negative bacterial infections

100%

Lugowski C.

Acta Biochimica Polonica

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1995

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tom 42

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nr 1

Endotoxins are responsible for initiation of septic shock which increases the number of fatalities in Gram-negative bacteremia among hospital patients. The morality from septic shock is still high despite recent developments in antibiotic therapy because antibiotics are unable to decrease the level of free lipopolysaccharide in the blood stream. Another approach to the treatment and prevention of septicaemia involves stimulation of an immune response against LPS. It was found that immunization with the core structures of endotoxin conjugated with proteins protected animals against infections and endotoxic shock. Anticonjugate sera are of great interest because they are directed against conserved parts of LPS and therefore could have cross-reactive and cross-protective properties with respect to many Gram-negative rods.

4

The role of antibiotic therapy in the prevention and treatment of MOF in severe acute pancreatitis

100%

Puolakkainen P., Hietaranta A., Kemppainen E., Kivilaakso E.

Journal of Physiology and Pharmacology. Supplement

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1998

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tom 49

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nr 2

5

Two separate cases of extrauterine pregnancy in queens

84%

Dzieciol M., Nizanski W., Ochota M., Blasiak K., Kozdrowski R., Stanczyk E., Twardon J.

Electronic Journal of Polish Agricultural Universities. Series Veterinary Medicine

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2012

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tom 15

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nr 2

6

Optimizing the European Regulatory Framework for sustainable bacteriophage therapy in human medicine

84%

Verbeken G., Pirnay J.-P., De Vos D., Jennes S., Zizi M., Lavigne R., Casteels M., Huys I.

Archivum Immunologiae et Therapiae Experimentalis

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2012

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tom 60

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nr 3

7

Possibilities of application of recombined lysostaphin as an alternative agent in the therapy of Staphylococcus aureus mastitis

84%

Jakubczak A., Szweda P., Kur J., Kleczkowski M., Frankowska A.

Advances in Agricultural Sciences

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2010

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tom 13

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nr 1

8

Antibacterial activity of ciprofloxacin and trimethoprim, alone and in combination, against Vibrio cholerae O1 biotype E1 Tor serotype Ogawa isolates

84%

Mandal S., Pal N. K., Chowdhury I. H., Debmandal M.

Polish Journal of Microbiology

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2009

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tom 58

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nr 1

57-60

In this communication, the ciprofloxacin-trimethoprim (Cp-Tm) combination showed synergistic (Fractional Inhibitory Concentration, FIC index 0.399) and additive (FIC index 0.665-0.83) effects against Vibrio cholerae O1 biotype El Tor serotype Ogawa isolates having Cp MICs 10 μg/ml and Cp 0.66 μg/ml, respectively, following agar dilution checkerboard method. The time-kill study results demonstrated synergy between Cp and Tm against both groups of isolates providing 2.04 log₁₀ (for strain with Cp MIC 0.66 μg/ml) and 3.12 log₁₀ (for strain with Cp MIC 10 μg/ml) decreases in CFU/ml between the combination and its most active compound. Thus, the findings of the present study suggest an introduction of Cp-Tm combination treatment regimen against drug resistant cholera and this in turn will help in combating the drug resistance of V. cholerae O1 biotype El Tor serotype Ogawa.

9

Treatment of drug-induced agranulocytosis with colony stimulating factors [G-CSF or GM-CSF]

84%

Gora-Tybor J., Krykowski E., Robak T.

Archivum Immunologiae et Therapiae Experimentalis

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1996

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tom 44

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nr 4

10

Prevention of Lyme disease: promising research or sisyphean task?

67%

Krupka M., Zachova K., Weigl E., Raska M.

Archivum Immunologiae et Therapiae Experimentalis

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2011

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tom 59

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nr 4

11

Comparison of PCR, fluorescent in situ hybridization and blood cultures for detection of bacteremia in children and adolescents during antibiotic therapy

67%

Zrodlowski T. W., Jurkiewicz-Badacz D., Sroka-Oleksiak A., Salamon D., Bulanda M., Gosiewski T.

Polish Journal of Microbiology

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2018

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tom 67

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nr 4

The gold standard in microbiological diagnostics of bacteremia is a blood culture in automated systems. This method may take several days and has low sensitivity. New screening methods that could quickly reveal the presence of bacteria would be extremely useful. The objective of this study was to estimate the effectiveness of these methods with respect to blood cultures in the context of antibiotic therapy. Blood samples from 92 children with sepsis were analyzed. Blood cultures were carried out in standard automated systems. Subsequently, FISH (Fluorescent In-Situ Hybridization) and nested multiplex-real-time-PCR (PCR) were performed. Blood cultures, FISH and PCR yielded positive results in 18%, 39.1%, and 71.7% of samples, respectively. Significant differences were found between the results obtained through culture before and after induction of antibiotherapy: 25.5% vs. 9.7%. There was no significant difference in FISH and PCR results in relation to antibiotics. The three methods employed demonstrated significant differences in detecting bacteria effectively. Time to obtain test results for FISH and PCR averaged 4–5 hours. FISH and PCR allow to detect bacteria in blood without prior culture. These methods had high sensitivity for the detection of bacteremia regardless of antibiotherapy. They provide more timely results as compared to automated blood culture, and may be useful as rapid screening tests in sepsis.

12

Immunomodulatory effects of Lactobacillus plantarum and Helicobacter pylori CagAplus on the expression of selected superficial molecules on monocyte and lymphocyte and the synthesis of cytokines in whole blood culture

67%

Wiese M., Eljaszewicz A., Andryszczyk M., Gronek S., Gackowska L., Kubiszewska I., Kaszewski W., Helmin-Basa A., Januszewska M., Motyl I., Wieczynska J., Michalkiewicz J.

Journal of Physiology and Pharmacology

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2012

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tom 63

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nr 3

13

The effect of nonsurgical periodontal therapy on HNP1-3 level in gingival crevicular fluid of chronic periodontitis patients

67%

Dolinska E., Skurska A., Pietruska M., Dymicka-Piekarska V., Milewski R., Pietruski J., Sculean A.

Archivum Immunologiae et Therapiae Experimentalis

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2017

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tom 65

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nr 4

14

Endoscopic examination of larynx, trachea and bronchi in cats

67%

Kubiak K., Nicpon J., Jankowski M., Spuzak J., Dzimira S.

Electronic Journal of Polish Agricultural Universities. Series Veterinary Medicine

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2003

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tom 06

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nr 2

15

Recurrent furunculosis: I. Granulocyte function and cell-mediated immunity in young male patients

67%

Samochocki Z., Szmigielski S., Bacz-Malinowska M., Sokolska G., Soroko W., Jeljaszewicz J., Pulverer G.

Advances in Agricultural Sciences

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1992

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tom 01

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nr 1

16

Comparison of therapeutic effectiveness of ampicilin and immunoactive peptide FK-156 in treatment of bronchopneumonia enzootica vitulorum

67%

Furowicz A. J., Czernomysy-Furowicz D., Grupinski T., Dabrowski W.

Advances in Agricultural Sciences

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1992

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tom 01

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nr 1

17

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

PCR for identification and typing of Helicobacter pylori isolated from children

67%

Dzierzanowska D., Gzyl A., Rozynek E., Augustynowicz E., Wojda U., Celinska-Cedro D., Sankowska M., Wadstrom T.

Journal of Physiology and Pharmacology

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1996

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tom 47

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nr 1

18

Problematyka mastitis u jałówek

59%

Smulski S.

Lecznica Dużych Zwierząt. Ogólnopolski Kwartalnik dla Lekarzy Weterynarii

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2015

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tom 10

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nr 1

19

Kolibakteriozy świń - wskazówki diagnostyczne i terapeutyczne

51%

Jablonski A., Cybulski P.

Lecznica Dużych Zwierząt. Ogólnopolski Kwartalnik dla Lekarzy Weterynarii

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2018

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tom 13

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nr 4

20

Odpowiedzialne stosowanie antybiotyków

51%

Pejsak Z.

Lecznica Dużych Zwierząt. Ogólnopolski Kwartalnik dla Lekarzy Weterynarii

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2015

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tom 10

|

nr 2

Ograniczanie wyników

Antibiotic therapy and fat digestion and absorption in cystic fibrosis

Local antibiotic therapy of the respiratory system infections in mechanically ventilated patients

Immunotherapy in Gram-negative bacterial infections

The role of antibiotic therapy in the prevention and treatment of MOF in severe acute pancreatitis

Two separate cases of extrauterine pregnancy in queens

Optimizing the European Regulatory Framework for sustainable bacteriophage therapy in human medicine

Possibilities of application of recombined lysostaphin as an alternative agent in the therapy of Staphylococcus aureus mastitis

Antibacterial activity of ciprofloxacin and trimethoprim, alone and in combination, against Vibrio cholerae O1 biotype E1 Tor serotype Ogawa isolates

Treatment of drug-induced agranulocytosis with colony stimulating factors [G-CSF or GM-CSF]

Prevention of Lyme disease: promising research or sisyphean task?

Comparison of PCR, fluorescent in situ hybridization and blood cultures for detection of bacteremia in children and adolescents during antibiotic therapy

Immunomodulatory effects of Lactobacillus plantarum and Helicobacter pylori CagAplus on the expression of selected superficial molecules on monocyte and lymphocyte and the synthesis of cytokines in whole blood culture

The effect of nonsurgical periodontal therapy on HNP1-3 level in gingival crevicular fluid of chronic periodontitis patients

Endoscopic examination of larynx, trachea and bronchi in cats

Recurrent furunculosis: I. Granulocyte function and cell-mediated immunity in young male patients

Comparison of therapeutic effectiveness of ampicilin and immunoactive peptide FK-156 in treatment of bronchopneumonia enzootica vitulorum

PCR for identification and typing of Helicobacter pylori isolated from children

Problematyka mastitis u jałówek

Kolibakteriozy świń - wskazówki diagnostyczne i terapeutyczne

Odpowiedzialne stosowanie antybiotyków