The synthesis of the new derivatives of 1,3,5-triazine was presented. The obtained compounds were biologically evaluated under glasshouse conditions. Some of them showed phytocidal activity on the bio indicators in pre- and post-emergence treatments. Compound IPO-11407 (2-methoxy-4-methylamine-6-thioalkyl-l,3,8-triazine) was distinguished by good phytocidal activity and was qualified to the II-nd stage of the screening research. Herbicidal activity of this compound on some weed species at higher rates was good but it was distinctly decreasing at the lower doses.