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1
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Non-responsiveness and tachyphylaxis to anti-vascular endothelial growth factor treatment in naive patients with exudative age-related macular degeneration

100%
Zuber-Laskawiec K., Kubicka-Trzaska A., Karska-Basta I., Pociej-Marciniak W., Romanowska-Dixon B.
Journal of Physiology and Pharmacology
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2019
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tom 70
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nr 5
2
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Altered serum levels of autophagy proteins Beclin-1 and mTOR in patients with exudative age-related macular degeneration

100%
Kubicka-Trzaska A., Zuber-Laskawiec K., Plutecka H., Romanowska-Dixon B., Sanak M., Kraska-Basta I.
Journal of Physiology and Pharmacology
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2021
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tom 72
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nr 1
3
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
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Prevalence of insomnia and depression in patients with age-related macular degeneration

86%
Nowak E., Kulik A., Wrobel J., Nowak G., Nowak D., Roczniak W., Josko-Ochojska J.
Health Problems of Civilization
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2018
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tom 12
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nr 4
Background. Age Related Macular Degeneration (AMD) affecting the organ of vision, impairs central vision. The study objective was (1) to define the prevalence of sleep disorders and depressive symptoms in patients with AMD, (2) to assess the relationship of depressive symptoms and insomnia with chosen demographic data, (3) to assess a potential correlation of the exacerbating vision quality with depressive symptoms and sleep disorders. Material and methods. The study involved 105 patients, women and men aged 45-88. Patients were asked to complete an original questionnaire subjected to validation, the Beck Depression Inventory and the Athens’s Insomnia Scale. Results. The results were analysed statistically, showing that 71% of the respondents had insomnia and 70% suffered from depression. The patients’ age, time from the diagnosis, marital and occupational status were not found to be related to depression or sleep disorders. Type of education, financial status and family support were significantly correlated with the prevalence of depression and sleep disorders. No correlation was observed between the exacerbation of vision disorders and enhanced depressive symptoms and insomnia. However, such correlation was noted with subjective stress reactions. Conclusions. Since patients with AMD are at a greater risk of sleep disorders and depression they should remain under professional care of a multidisciplinary team, including an ophthalmologist, a family doctor, a psychiatrist and a psychologist.
4
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Dietary sources of lutein in adults suffering eye disease (AMD/cataracts)

72%
Sulich A., Hamulka J., Nogal D.
Roczniki Państwowego Zakładu Higieny
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2015
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tom 66
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nr 1
Background. Epidemiological studies indicate that by consuming 6-14 mg lutein daily, the risk of acquiring eye diseases like age-related macular degeneration (AMD) or cataracts becomes reduced. Their symptoms can also by such means be alleviated and treatment improved. Objectives. To estimate dietary intakes of lutein obtained from foodstuffs and supplements along with determining its main sources in selected groups of adults suffering from eye disease and healthy controls. Material and Methods. The study was performed in Warsaw and its neighbourhoods during 2008-12. Subjects were 375 adults aged 50-97 years, of whom half had been diagnosed with AMD and/or cataracts; constituting the test group. Dietary intakes of lutein were assessed by Food Frequency Questionnaire Method whilst interview questionnaires assessed the intake of supplements. Results. Overall, the average dietary intake of lutein from foodstuffs was 2.5 mg daily, with the test group being significantly higher than healthy controls (2.9 vs 2.1 mg daily). Women’s intakes were also higher than in men (2.9 vs 2.1 mg daily), as were those possessing higher or secondary education compared to the others with primary or vocational education (2.7 vs 2.3 mg daily). Fresh vegetables were found to be the main dietary sources of lutein that included green leafy vegetables and frozen vegetables, constituting respectively 63% and 13% of the dietary intake. Dietary supplements containing lutein were taken by 109 subjects of whom most had eye disease (over 80%); where the average daily consumption of lutein from this source was 6.5 mg. Conclusions. For older people, the dietary intake of lutein from foodstuffs may be insufficient to prevent eye disease. Taking daily dietary supplements would thus be indicated to make up such deficiencies of lutein.
5
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Differences in anti-endothelial and anti-retinal antibody titers: implications for the pathophysiology of acute and chronic central serous chorioretinopathy

72%
Karska-Basta I., Pociej-Marciak W., Chrzaszcz M., Wilanska J., Jager M. J., Markiewicz A., Romanowska-Dixon B., Sanak M., Kubicka-Trzaska A.
Journal of Physiology and Pharmacology
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2020
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tom 71
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nr 2
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