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  1. 16 Journal of Physiology and Pharmacology

  2. 5 Journal of Physiology and Pharmacology. Supplement

  3. 1 Archivum Immunologiae et Therapiae Experimentalis

  4. 1 Folia Biologica

  5. 1 Roczniki Państwowego Zakładu Higieny

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  1. 3 Malecka-Panas E.

  2. 3 Sakr H. F.

  3. 2 Baranowska B.

  4. 2 Bik W.

  5. 2 Lekstan A.

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  1. 5 2020

  2. 1 2019

  3. 2 2017

  4. 3 2015

  5. 1 2014

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1
Content available remote

Neuroendocrine control of metabolic homeostasis in Polish centenarians

100%
Baranowska B., Bik W., Baranowska-Bik A., Wolinska-Witort E., Szybinska A., Martynska L., Chmielowska M.
Journal of Physiology and Pharmacology. Supplement
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2006
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tom 57
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nr 6
55-61
Neuropeptides play a pivotal role in the control of metabolic homeostasis. We aimed to evaluate the release of neuropeptides involved in the control of energy homeostasis in relation to metabolic status in aging humans. The study group consisted of 183 women: 75 centenarians (above 100 yrs old), 26 elderly women (below 70 yrs), 45 younger women (mean 26 yrs) and 37 obese women (mean 41.6 yrs). Fasting plasma concentration of leptin, adiponectin, ghrelin active, neuropeptide Y (NPY) and insulin were measured. Our results showed several differences in the metabolic and neurohormonal status in the centenarian group. The incidence of hypertension, glucose intolerance, insulin resistance and dyslipidemia was lower compared with obese women. Leptin and NPY concentrations were significantly lower than in elderly and obese subjects. Moreover, NPY level was higher than that in the younger group. Plasma adiponectin values were higher than in any of the other group. Insulin levels were significantly lower compared with the young and obese groups. Furthermore, a negative correlation was found between adiponectin and HOMA-IR, and adiponectin and insulin. Ghrelin active concentrations were significantly lower compared with the young subjects. However, ghrelin levels were higher than in obese subjects. We conclude that altered neuropeptide activity in centenarians may play a role in the mechanisms contributing to prolonged survival.
2
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The assessment of serum concentration of adiponectin, leptin and serum carbohydrate antigen-19.9 in patients with pancreatic cancer and chronic pancreatitis

100%
Dranka-Bojarowska D., Lekstan A., Olakowski M., Jablonska B., Lewinski A., Musialski P., Sobczyk W., Kapalka A., Lampe P.
Journal of Physiology and Pharmacology
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2015
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tom 66
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nr 5
3
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A novel pathophysiological-based panel of biomarkers for the diagnosis of nonalcoholic steatohepatitis

100%
Grigorescu M., Crisan D., Radu C., Grigorescu M. D., Sparchez Z., Serban A.
Journal of Physiology and Pharmacology
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2012
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tom 63
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nr 4
4
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Assessment of leptin-to-adiponectin ratio in prediction of insulin resistance and nutrition status in a geriatric female population

100%
Biercewicz M., Slusarz R., Kedziora-Kornatowska K., Filipska K., Bielawski K., Ruszkowska-Ciastek B.
Journal of Physiology and Pharmacology
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2020
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tom 71
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nr 1
5

Decreased serum adiponectin reflects low vitamin D, high interleukin 6, and poor physical performance in knee osteoarthritis

100%
Udomsinprasert W., Manoy P., Yuktanandana P., Tanavalee A., Anomasiri W., Honsawek S.
Archivum Immunologiae et Therapiae Experimentalis
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2020
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tom 68
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nr 3
6
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Total and high molecular weight adiponectin levels in the rat model of post-myocardial infarction heart failure

100%
Kalisz M., Baranowska B., Wolinska-Witort E., Maczewski M., Mackiewicz U., Tulacz D., Gora M., Martynska L., Bik W.
Journal of Physiology and Pharmacology
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2015
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tom 66
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nr 5
7
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Modulatory effect of concomitant administration of sitagliptin and vitamin E on inflammatory biomarkers in rats fed with high fat diet: role of adiponectin

100%
Sakr H. F., Abbas A. M., Khalil K., Shata A. M.
Journal of Physiology and Pharmacology
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2019
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tom 70
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nr 6
8

Expression of leptin, NGF and adiponectin in metabolic syndrome

100%
Atanassova P., Hrischev P., Orbetzova M., Nikolov P., Nikolova J., Georgieva E.
Folia Biologica
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2014
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tom 62
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nr 4
9
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Maternal first trimester parameters in the prediction of excessive fetal growth in pregnant women with metabolic syndrome

100%
Migda M., Migda M. S., Migda B., Wender-Ozegowska E.
Journal of Physiology and Pharmacology
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2017
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tom 68
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nr 6
10
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Adiponectin and leptin receptors expression in Barrett's esophagus and normal squamous epithelium in realtion to central obesity status

100%
Mokrowiecka A., Sokolowska M., Luczak E., Dudojc M., Wieczfinska J., Kacprzak D., Wierzchniewska-Lawska A., Pawliczak R., Malecka-Panas E.
Journal of Physiology and Pharmacology
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2013
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tom 64
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nr 2
11
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Serum betatrophin and irisin levels in hepatocellular carcinoma

100%
Pazgan-Simon M., Zuwala-Jagiello J., Menzyk T., Bator M., Derra A., Lekstan A., Grzebyk E., Simon K., Kukla M.
Journal of Physiology and Pharmacology
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2020
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tom 71
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nr 1
12
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Adiponectin, resistin and subclinical inflammation - the metabolic burden in Launois Bensaude syndrome, a rare form of obesity

100%
Harsch I. A., Bergmann T., Koebnick C., Wiedmann R., Ruderich F., Hahn E. G., Konturek P. C.
Journal of Physiology and Pharmacology. Supplement
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2007
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tom 58
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nr 1
65-76
13
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Content available

Effect of diet and other factors on serum adiponectin concentrations in patients with type 2 diabetes

100%
Ostrowska L., Fiedorczuk J., Adamska E.
Roczniki Państwowego Zakładu Higieny
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2013
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tom 64
|
nr 1
Background. Adiponectin is a protein specific to visceral adipose tissue where its concentrations are reduced in type 2 diabetes and obesity. Many factors also determine serum levels of adiponectin such as gender, BMI, as well as diet. Objective. To compare the effects of consuming certain key foodstuff products on serum adiponectin concentrations between diabetic patients and suitable controls. Material and methods. A survey and laboratory testing was performed on 72 patients of whom (n = 21) were diabetics, whilst the control group, (n = 51) non-diabetics. Eating habits were assessed and serum adiponectin was measured in all cases. Results. Diabetic patients had significantly lower adiponectin levels compared to the control group; respectively (23.5±21.1 μg/ml vs. 36.5±21.1 μg/ml; p=0.02). Furthermore, women had higher concentration than men; respectively (41.3 μg/ml± 20.1 μg/ml vs. 22.0 μg/ml± 14.8 μg/ml; p=0.000). A high consumption of foodstuffs such as vegetables, vegetable oils, coffee and tea positively correlated with adiponectin concentration in serum, whilst a negative correlation was seen with consumptions of mixed bread, fried and baked dishes, alcohol, nuts and seeds. Conclusions. Serum adiponectin levels are related to factors such as gender, (higher in women), BMI, (higher in persons with normal body weight) and whether diabetic, (lower in people with diabetes). Multiple correlations were observed between the consumption of foodstuff product groups and serum adiponectin concentration. It is thereby suggested, that adiponectin could have a significant role to play in the treatment and prevention of diabetes and obesity.
14
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Weight loss-dependent and -independent effects of moderate calorie restriction on endothelial cell markers in obesity

100%
Korybalska K., Luczak J., Swora-Cwynar E., Kanikowska A., Czepulis N., Kanikowska D., Skalisz H., Breborowicz A., Grzymislawski M., Witowski J.
Journal of Physiology and Pharmacology
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2017
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tom 68
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nr 4
15
Content available remote

Short term 13-cis-retinoic acid treatment at therapeutic doses elevates expression of leptin, GLUT4, PPARgamma and aP2 in rat adipose tissue

80%
Krskova-Tybitanclova K., Macejova D., Brtko J., Baculikova M., Krizanova O., Zorad S.
Journal of Physiology and Pharmacology
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2008
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tom 59
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nr 4
731-743
Temporary defects in the plasma lipid and glucose homeostasis are frequent complication accompanying chronic treatment with 13-cis-retinoic acid (13cRA). White adipose tissue acts as an endocrine organ producing a variety of hormones (adipocytokines) including leptin, adiponectin, tumor-necrosis factor alpha (TNF) and angiotensin II (Ang II), which influence lipid metabolism, systemic insulin sensitivity and inflammation. To study the effect of a short-term 13cRA administration on metabolism of epididymal fat tissue, we treated Wistar rats with five identical therapeutic doses of 13cRA (0.8 mg/kg b.w.) by gavage during a period of 10 days. Expression of adiponectin, leptin, TNF and selected proteins such as adipocyte fatty acid binding protein (aP2), insulin-dependent glucose transporter GLUT4, peroxisome proliferator-activated receptor gamma (PPAR) and retinoid X receptors (RXRs) was investigated using RT-PCR. Short-term treatment with therapeutic doses of 13cRA caused significant increase of the aP2, PPAR and moderately RXR gene expression. Similarly, the relative amount of mRNA for leptin and GLUT4 was increased, while the TNF transcript was decreased after treatment with 13cRA. The gene expression and plasma concentration of adiponectin were without any significant changes. Since local adipose renin-angiotensin system (RAS) has been presumed to be involved in the regulation of fat tissue metabolism, we also investigated the gene expression of RAS components in epididymal fat depot. Our data has shown that 13cRA elevated Ang II receptor type 1 (AT1 receptor) - at both, mRNA and protein level. Thus, our results demonstrate that short-term 13cRA treatment is inducing alterations in fat tissue metabolism in relation to stimulated adipogenesis.
16
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The impact of physical activity and nutrition on inflammatory bowel disease: the potential role of cross talk between adipose tissue and skeletal muscle

80%
Bilski J., Mazur-Bialy A. I., Wierdak M., Brzozowski T.
Journal of Physiology and Pharmacology
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2013
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tom 64
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nr 2
17
Content available remote

Metabolic cardio- and reno-protective effects of empagliflozin in a prediabetic rat model

80%
Huttl M., Markova I., Miklankova D., Oliyarnyk O., Trnovska J., Kucera J., Sedlacek R., Haluzik M., Malinska H.
Journal of Physiology and Pharmacology
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2020
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tom 71
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nr 5
18
Content available remote

Modulation of metabolic and cardiac dysfunctions by swimming in overweight rats on a high cholesterol and fructose diet: possible role of adiponectin

80%
Sakr H. F.
Journal of Physiology and Pharmacology
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2013
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tom 64
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nr 2
19
Content available remote

Adipohormones as prognostic markers in patients with nonalcoholic steatohepatitis [NASH]

80%
Krawczyk K., Szczesniak P., Kumor A., Jasinska A., Omulecka A., Pietruczuk M., Orszulak-Michalak D., Sporny S., Malecka-Panas E.
Journal of Physiology and Pharmacology. Supplement
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2009
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tom 60
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nr 3
71-75
20
Content available remote

Role of adipokines in the assessment of severity and predicting the clinical course of acute pancreatitis

80%
Wos-Wroniewicz E., Caban M., Malecka-Panas E.
Journal of Physiology and Pharmacology
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2020
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tom 71
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nr 5
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