The field experiment was conducted during four years (1995-1998) in an apple orchard in Central Poland. It was found that predatory mite Typhlodromus pyri Scheut (Phytoseiidae) introduced to the orchard, provided excellent biological control of spider mites (Panonychus ulmi Koch, Tetranychus urticae Koch) on plot do not treated against pests and in first year on "integrated" plots sprayed according to different schedules with selective insecticides. Fungicide methiram (Polyram-Combi) and aphicide triazamate (Azetc) considered as selective ones in presented experiment showed high toxicity to T. pyri. Predatory mite Zetzelia mali Ewing (Stigmaeidae) naturally occuring in the orchard, exhibited high resistance to above mentioned pesticides.