Witchweeds, especially Striga spp. (Scrophulariaceae), have become a major pest for cereal crops in Africa. Presently there are no efficient management methods to alleviate the agronomical problem posed by witchweeds. In a multidisciplinary research program addressed to the Striga problem, we conducted histological work to study the effects of a weevil (Smicronyx spp.) on Striga seed production. The embryological development of Striga hermonthica was studied in normal (unattacked) and attacked (by Smicronyx weevils) capsules. The results on the impact of Smicronyx weevils on Striga fruit are described. Our findings should be of interest in implementing a Striga management program based on seed bank control. Seed bank management should be integrated with other control tactics to achieve a practical and agronomical impact on Striga populations.