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The study was based on field research. The main goal of the work was to determine the level of consumer awareness of regional products and to examine the statistical relationship between the age and education level of respondents and their declaration of purchasing this type of product. Data collection was performed in Sudeten districts, because the described study was part of a research project concerning the introduction of a new regional product „Sudeten Beef” into this area. The study was conducted in 2012 using direct interviews with 219 respondents. On the basis of the investigation it could be said that the surveyed respondents had little awareness of regional products. The statistical analysis confirmed a weak correlation between age and level of education and declarations of purchasing regional products. This study is of a preliminary character and the results are not representative of the whole Polish population, but they should be regarded as a good starting point for further in-depth research.
The aim of the study was to investigate the distribution of the circle of Willis variants in Polish population by means of computed tomography angiography (CTA). The results were then analysed and compared with another study that used similar methods but that was carried out on an ethnically distinct population. Patients presenting with intracranial pathology were excluded from the initial study population. In total, 250 CTA belonging to 129 female and 121 male patients were reviewed. A modified classification system of the circle was proposed, which took into consideration the anterior and the posterior aspects of the circle individually. The typical variant of Willis’s circle occurred in 16.80% of cases. The anterior and the posterior portions of the circle were normal in 47.20% and 26.80% of the patients respectively. As for the anterior part, lack of the anterior communicating artery was the most frequent abnormality (22.80%). Bilateral absence of posterior communicating arteries was the most common anomaly in the posterior part of the circle (29.20%). This type of anomaly was also the most common, when taking into consideration the entire circle (12.00%). There were statistically significant differences between the age groups and genders when considering the occurrence of an incomplete circle. Overall, a substantial proportion of patients manifested clinically important variants that were incapable of providing collateral circulation. Comparison with other imaging-based and cadaveric studies revealed noticeable differences, that may have resulted from the variable technical features of other studies or other factors such as the ethnical origins of the studied populations. (Folia Morphol 2013; 72, 4: 293–299)
Screening for molecular changes within the adenomatous polyposis coli (APC) gene, exons 11-14 and the 5’ half of exon 15, encompassing the mutation cluster region within exon 15, was performed in 30 patients with Familial Polyposis Coli (FAP). All patients were studied by heteroduplex analysis (HA) and single strand conformation polymorphism (SSCP) and molecular changes were found in 7 cases. Protein truncation test (PTT) has been performed in 17 cases in which mutations have not been found earlier, and shortening of protein product was noted in 2 cases. In three cases common deletion of 5 bp at codon 1309 and in one 5 bp deletion at codon 1061 were found. In other cases the molecular changes were demonstrated as heteroduplexes in exon 14 (1 patient), in segments E and F (one patient each) of exon 15, and in two cases the heteroduplexes were within the overlapping sequences of segments E/F and F/G of exon 15, respectively. In families where the molecular changes were found by HA, 7 persons at high risk for FAP were found and advised to undergo regular endoscopic examinations. In three persons at risk the transfer of mutation was excluded.
Factor V Leiden (G1691A FV mutation) is a widely acknowledged risk factor of deep vein thrombosis, including pulmonary embolism as the most serious complication. However, its high prevalence of ~5% in the Caucasian population might be related to an unknown evolutionary advantage. It might exert a beneficial effect on the carrier, e.g. protecting women from excessive bleeding during labour or allowing increased survival in severe sepsis or with other inflammatory diseases. The aim of our study was to verify or contradict the hypothesis of a favourable association between the A allele (A1691) and longevity in the Polish population. For this purpose, the G1691A mutation was analyzed by PCR-RFLP in 1016 Poles: 400 neonates (187 female and 312 male), 184 healthy adults (129 female and 55 male), and 432 long-lived individuals (age ≥ 95 years: 343 women and 89 men). Frequencies of G1691A carriers and the A1691 allele in long-lived individuals (0.2% and 0.1%, respectively) were significantly lower than in neonates (4.2% and 2.2%, respectively) and adults (3.3% and 1.6%). The frequency of the G1691A factor V Leiden mutation decreased with age, which indicates a shorter survival time among A1691 allele carriers in the Polish population.
The aims of this study were to analyse the structure of Polish dairy goat population and to estimate the non-genetic and genetic sources of variation in five milk traits. The data set comprised 18,563 lactation records of 8,938 dairy goats, while the pedigree file covered information on 13,159 animals 6 generations deep. To estimate the environmental effects the GLM procedure, using a model with the random effect on the herd-sire interaction, the fixed effects of herd-year-season of kidding interaction, breed, litter size, parity, year of birth and regression on day-in-milk. To estimate the co(variance) of the components of milk, fat, and protein yields, as well as fat and protein contents the REML method based on the repeatability animal model was applied. The average inbreeding coefficient was 0.61% (sd=3.12%). Milk, fat and protein yields were affected by all the factors except for breed. The nanny goats with more than two kids had higher milk, fat and protein yields,but they had a lower percentage of milk components than those with one kid or twins. The goats in their first lactation had the lowest milk, fat and protein yields, but the highest fat content. The heritability estimates were moderate (0.21, 0.18, 0.19 for milk, fat and protein yields, respectively).Repeatability estimates ranged from 0.30 for milk, 0.28 for fat, and 0.27 for protein yields, and 0.25 and 0.28 for fat and protein contents. Genetic correlations between milk yield and fat and protein contents were negative and moderate (-0.27 and -0.30), between fat and protein contents (0.58) while those between yields were ranged from 0.71 to 0.86. In turn, correlations between fat yield and its content, and protein yield and its content were positive and moderate (0.35, 0.23).
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