Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: Polish centenarian

Sortuj według:

Ogranicz wyniki do:

Neuroendocrine control of metabolic homeostasis in Polish centenarians

100%

Baranowska B., Bik W., Baranowska-Bik A., Wolinska-Witort E., Szybinska A., Martynska L., Chmielowska M.

Journal of Physiology and Pharmacology. Supplement

2006

tom 57

nr 6

55-61

Neuropeptides play a pivotal role in the control of metabolic homeostasis. We aimed to evaluate the release of neuropeptides involved in the control of energy homeostasis in relation to metabolic status in aging humans. The study group consisted of 183 women: 75 centenarians (above 100 yrs old), 26 elderly women (below 70 yrs), 45 younger women (mean 26 yrs) and 37 obese women (mean 41.6 yrs). Fasting plasma concentration of leptin, adiponectin, ghrelin active, neuropeptide Y (NPY) and insulin were measured. Our results showed several differences in the metabolic and neurohormonal status in the centenarian group. The incidence of hypertension, glucose intolerance, insulin resistance and dyslipidemia was lower compared with obese women. Leptin and NPY concentrations were significantly lower than in elderly and obese subjects. Moreover, NPY level was higher than that in the younger group. Plasma adiponectin values were higher than in any of the other group. Insulin levels were significantly lower compared with the young and obese groups. Furthermore, a negative correlation was found between adiponectin and HOMA-IR, and adiponectin and insulin. Ghrelin active concentrations were significantly lower compared with the young subjects. However, ghrelin levels were higher than in obese subjects. We conclude that altered neuropeptide activity in centenarians may play a role in the mechanisms contributing to prolonged survival.

Anthropometric chest structure of Polish centenarians

100%

Broczek K. M., Pawlinska-Chmara R., Kupisz-Urbanska M., Mossakowska M.

Journal of Physiology and Pharmacology. Supplement

2005

tom 56

nr 4

9-13

The aim of the study was to analyze somatometric chest structure in persons aged over 100 years. The study group included 83 women and 13 men, aged 100-108 yr (median age -100.8 yr), who participated in the scientific project: 'Genetic and Environmental Factors of Longevity of Polish Centenarians' in 2002-2004. The Rohrer index of chest structure using acromion-acromion length and body height were compared with the results of pulse oximetry, spirometry, and the level of general physical activity. The majority of the centenarians had a pyknic structure of the chest, most likely as a result of a progressive reduction of body height and chest stooping. In comparison with the women who had marked alterations of chest structure, females with less profound changes had a lower respiratory rate, better tolerance of exercise, higher forced vital capacity, and a higher physical activity. A small number of male subjects studied made it impossible to analyze statistical correlations in this group. We conclude that there is a need to redefine anthropometric indices for a reliable assessment of chest structure in senescent subjects.

Ograniczanie wyników

2 Journal of Physiology and Pharmacology. Supplement

1 Baranowska B.

1 Baranowska-Bik A.

1 Bik W.

1 Broczek K. M.

1 Chmielowska M.

1 Kupisz-Urbanska M.

1 Martynska L.

1 Mossakowska M.

1 Pawlinska-Chmara R.

1 Szybinska A.

1 Wolinska-Witort E.

1 2006

1 2005

Wyniki wyszukiwania

Neuroendocrine control of metabolic homeostasis in Polish centenarians

Anthropometric chest structure of Polish centenarians