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The effect of blood-cycle synchronicity on the chloroquine sensitivity of Plasmodium chabaudi

100%

Tahar R., Gautret P., Landau I.

Acta Parasitologica

1995

tom 40

nr 2

Plasmodium chabaudi, a rodent malaria parasite with a synchronous asexual cycle in the blood, depending on the host’s circadian rhythm, was desynchronized by modifying its normal timing: blood taken from a donor mouse in the morning was kept 8 h at +4°C and inoculated in the evening into naive mice. When the infection had become asynchronous (from day 4 to day 7) mice were treated with a single dose of chloroquine. The efficacy of chloroquine was lower in mice with an asynchronous infection than in the control mice with a normally synchronous infection.

The production of gametocytes by rodent Plasmodium species in mice during phenylhydrazine induced reticulocytosis

67%

Gautret P., Coquelin F., Chabaud A. G., Landau I.

Acta Parasitologica

1997

tom 42

nr 2

A reticulocytosis induced by injections of phenylhydrazine to white mice enhanced the gametocyte production of Plasmodium berghei. Gametocytogenesis of P. yoelii and P. vinckei petteri were not affected by phenylhydrazine treatment.

Ograniczanie wyników

2 Acta Parasitologica

2 Gautret P.

2 Landau I.

1 Chabaud A. G.

1 Coquelin F.

1 Tahar R.

1 1997

1 1995

Wyniki wyszukiwania

The effect of blood-cycle synchronicity on the chloroquine sensitivity of Plasmodium chabaudi

The production of gametocytes by rodent Plasmodium species in mice during phenylhydrazine induced reticulocytosis