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Skuteczność Linco-Spectin w leczeniu i zapobieganiu dezynterii świń

100%

Szynkiewicz Z., Jakubowski T., Dziaba K., Binek M.

Medycyna Weterynaryjna

1988

tom 44

nr 09

Цель работы состояла в определении MIC линкомицина содержащегося в противоспирохеточных препаpатах, для штаммов Treponema hyodysenteriae, изолированных в Польше, а также в оценке профилактической и лечебной эффективности Linco-Spectin в борьбе с дизентерией свиней (DS), MIC 90 линкомицина для Т. hyodysenteriae составлял 20 µг/мл. Linco-Spectin 100 применили 2-кратно профилактически в течение 7—10 дней в корме в дозе 5 мг/кг М.Т., что предотвращало у 1040 свиней заболевание DS, Linco-Spectin 100, употребленный для лечения в течение 7 дней в дозе 10 мг/кг м.т. на 2 фермах (1057 свиней), вызывал исчезновение клиничеемких симптомов через 24—48 часов. На этих фермах не наблюдалось возвращение болезни. Похожие результаты получили на 6 фермах у 3253 свиней, где лечили больных DS свиней препаратом Linco-Spectin 44 в дозе 88 ppm в корме 5 дней. При употреблении же метронидазола отмечали повторные заболевания в стаде. Хорошие результаты профилактического употребления метронидазола против DS получили при дозе 20 мг/кг м.т. после ввода в течение 7 очередных дней. MIC для метронидазола составлял 0,1—1,5 µг/мл. Через некоторые время на тех же самых формах MIC для метронидазола составлял уже 15 µг/мл. Доза 20 мг/кг м.т., употребляемая в лечении, не предотвращала повторных заболеваний DS в стаде. Ронидазол в дозах, рекомендуемых проузводителем, был не эффективен в борьбе с DS MIC 220 составлял 7,5 µг/мл. Результаты работы внушаают, что Linco-Spectin является эффективным средством для предотвращения и лечении дизентерии свиней в Польше.

Ocena skutecznosci in vitro wybranych nowych antybiotykow w stosunku do terenowych szczepow Salmonella enteritidis izolowanych od drobiu

100%

Rzedzicki J., Furmaga J., Bos M.

Annales Universitatis Mariae Curie-Skłodowska. Sectio DD:Medicina Veterinaria

1995

tom 50

255-262

Ocena przydatnosci chemioterapeutykow w leczeniu doswiadczalnie wywolanego zapalenia pluc u swin na tle infekcji mieszanych

88%

Pejsak Z., Wasinski B., Trela T., Mokrzycka A.

Medycyna Weterynaryjna

1995

tom 51

nr 06

333-337

The objective of the work was to determine under experimental conditions, the clinical and economical effects of mixed infections of the respiratory system in pigs, and to estimate the therapeutical efficacy of selected chemiotherapeutics in the treatment of experimentally induced pneumonia. Forty-two piglets, about 25 kg each, were used for the experiment. The animals were free of Mycoplasma hyopneu- moniae (M.hp.), Pasteurella multocida (P.m.) and Bordetella bronchiseptica (B.b.). Pigs were randomly divided into 6 experimental groups and a control group. All the animals were infected on day 0 with a M.hp. suspension at a dose of 10 cfu/ml. One ml of the suspension was instilled into each nostril. Seven days later the animals were infected in the same way with B.b. at a dose of 10 cfu/ml; 24 hr later they received a suspension of a toxinogenic strain of P.m., which was given into each nostril in a dose of 10 cfu/ml. Seven days after the application of P.m. the treatment of the animals was started by administering to each group of animals feed or water containing one of the following chemiotherapeutics: enrofloxacin (Baytril), lincomycin + spectinomycin (Linco-Spectin 100), norfloxacin (Quin-Abic), chlortetracyc- line + Tiamutin (Tetramutin) or Tiamutin and Tylan. All the drugs were administered in doses recommended by the producers for 10 days. The efficacy of infection and treatment was determined on the basis of on the results of the following examinations: (1) bacteriological examinations; (2) post-slaughter determination of quantitative pathological lesions in the particular lung lobes; (3) dynamics of body weight gains, and (4) feed conversion per kg of body weight gain. The results of these investigations were as follows: 1. Almost in all cases the experimental infection of piglets appeared to be effective; 2. The administration of the antibiotics eliminated M.hp. in all piglets treated with Tetramutin and Linco-Spectin for 10 days; 3. The best results in the elimination of B.b. infections were obtained in piglets treated with a combination of lincomycin+spectinomycin and Tetramutin; 4. A combination of chlortetracycline and Tiamutin proved to be most effective in the treatment of the P.m. infections in the examined piglets. This bacterium was not found in any nasal swabs collected from piglets 3 weeks after finishing the treatment. Five weeks after infecting of the animals the body weight losses in untreated piglets were about 6 kg higher in comparison with the infected and treated animals. Feed conversion was also significantly worse: in the control group feed conversion per kg of body weight gain was 4.97 kg and in piglets treated with Tetramutin and Tiamutin it was 3.68 and 3.69 kg, respectively. Comparison of the results obtained in bacteriological and post-mortem examinations with those of body weight gains and feed conversion showed a high correlation between the healthy state of piglets and effectiveness of production.

Ograniczanie wyników

2 Medycyna Weterynaryjna

1 Annales Universitatis Mariae Curie-Skłodowska. Sectio DD:Medicina Veterinaria

1 Binek M.

1 Bos M.

1 Dziaba K.

1 Furmaga J.

1 Jakubowski T.

1 Mokrzycka A.

1 Pejsak Z.

1 Rzedzicki J.

1 Szynkiewicz Z.

1 Trela T.

1 Wasinski B.

2 1995

1 1988

Wyniki wyszukiwania

Skuteczność Linco-Spectin w leczeniu i zapobieganiu dezynterii świń

Ocena skutecznosci in vitro wybranych nowych antybiotykow w stosunku do terenowych szczepow Salmonella enteritidis izolowanych od drobiu

Ocena przydatnosci chemioterapeutykow w leczeniu doswiadczalnie wywolanego zapalenia pluc u swin na tle infekcji mieszanych