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1

Effect of L-carnitine on performance and dressing percentage of broiler chickens

100%
Michalczuk M., Lukasiewicz M., Niemiec J., Wnuk A., Mroczek-Sosnowska N.
Annals of Warsaw University of Life Sciences - SGGW. Animal Science
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2012
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tom 51
The study was conducted on 640 chickens randomly divided into two groups, each having four replications (4 control and 4 experimental - L-carnitine) with 80 chickens per pen. Chickens in the control (C) and experimental groups (E) received a feed of the same nutritional value, and chickens from the experimental group were supplemented with Aminocarnifarm (43.68% of L-carnitine) in drinking water (62.5 g per 100 l) during three periods: from 1 to 7, 21 to 28, and 36 to 42 days of age. The study evaluated the effect of L-carnitine supplemented to chickens on production results and results of slaughter analysis. It was found that Aminocarnifarm supplemented to drinking water improved feed conversion during the whole rearing period, reduced mortality, and contributed to increases in average body weight, dressing percentage and proportion of leg muscles (males), reduced the proportion of breast muscles (males and females), and decreased carcass fatness (males).
2
Content available remote

L-carnitine protects gastric mucosa by decreasing ischemia-reperfusion induced lipid peroxidation

100%
Derin N., Izgut-Uysal V. N., Agac A., Aliciguzel Y., Demir N.
Journal of Physiology and Pharmacology
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2004
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tom 55
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nr 3
Studies have shown that reactive oxygen metabolites and lipid peroxidation play important roles in ischemia-reperfusion injury in many organs such as heart, brain and stomach. The aim of this study is to evaluate the antioxidant effect of L-carnitine on gastric mucosal barrier, lipid peroxidation and the activities of antioxidant enzymes in rat gastric mucosa subjected to ischemia-reperfusion injury. Rats were subjected to 30 min of ischemia followed by 60 min of reperfusion. L-carnitine (100 mg/kg), was given to rats intravenously five minutes before the ischemia. In our experiment, lesion index, thiobarbituric acid reactive substances, prostaglandin E2 and mucus content in gastric tissue were measured. The results indicated that the lesion index and the formation of thiobarbituric acid reactive substances increased significantly with the ischemia-reperfusion injury in the gastric mucosa. L-carnitine treatment reduced these parameters to the values of sham operated rats. The tissue catalase and superoxide dismutase activities and prostaglandin E2 production decreased significantly in the gastric mucosa of rats exposed to ischemia-reperfusion. L-carnitine pretreatment increased the tissue catalase activity and prostaglandin E2 to the levels of sham-operated rats but did not change superoxide dismutase activity. There were no significant difference in glutathione peroxidase activity and mucus content between the groups in the gastric mucosa. In summary, L-carnitine pretreatment protected gastric mucosa from ischemia-reperfusion injury by its decreasing effect on lipid peroxidation and by preventing the decrease in prostaglandin E2 content of gastric mucosa.
3

Effect of dietary L-carnitine supplementation on sows performance

84%
Urbaityte R., Danyla L., Sederevicius A., Jeroch H.
Medycyna Weterynaryjna
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2006
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tom 62
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nr 05
527-530
The effect of L-carnitine supplementation during gestation and lactation on the performance parameters of sows was studied. The trial comprised a total of 73 sows that were divided into the control and treated groups; each was fed diets with and without supplemental L-carnitine during pregnancy (0 vs. 125 mg L-carnitine daily/sow) and lactation (0 vs. 250 mg L-carnitine daily/sow). L-carnitine supplementation resulted in the numerical increase of sow body weight at weaning (215.2±5.4 vs. 205.0±5.0, LSM±Se, p≥0.05), with a significantly expressed effect on sows born in 1998 (227.1±8.4 vs. 193.6±9.2, LSM±Se, p=0.01). There was a numerical increase in average number of total born and viable piglets per litter in treated sows (11.0±2.0 vs. 10.7±1.9, LSM±Se, p≥0.05; 10.8±2.1 vs. 10.4±1.9, LSM±Se, p≥0.05 respectively), although the tendency towards increasing the same parameters was determined in sows born in 1998 (11.00±0.54 vs. 9.82±0.59, LSM±Se, p=0.14; 10.9±0.6 vs. 9.5±0.6, LSM±Se, p=0.09). The total number of piglets which were smaller than 800g at birth tended to be lower (0.9±1.2 vs. 1.4±1.6, LSM±Se, p=0.08) and significantly different in sows born in 1998 (0.9±0.4 vs. 2.5±0.4, LSM±Se, p=0.01). The number of piglets fit for rearing was influenced by L-carnitine supplementation only in the sows born in 1998 (10.8±0.5 vs. 9.1±0.6, LSM±Se, p=0.03). The litter weight was not influenced by L-carnitine supplementation.
4
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Protective effects of L-carnitine on reproductive capacity in rats with diabetes

84%
Li X.-F., Shi Z.-D., Song H., Wang Y.-L., Li Q.-C., Diao X.-H., Pang Y.-W., Zhou S.-H., Liu H.-Y.
Journal of Physiology and Pharmacology
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2021
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tom 72
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nr 1
5

The antioxidant properties of carnitine in vitro

84%
Solarska K., Lewinska A., Karowicz-Bilinska A., Bartosz G.
Cellular and Molecular Biology Letters
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2010
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tom 15
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nr 1
90-97
Many of the effects of carnitine are ascribed to its antioxidant properties. The aim of this study was to evaluate the antioxidant properties of carnitine in vitro. Carnitine was found to decolorize ABTS•+, and to protect fluorescein against bleaching induced by AAPH-derived peroxyl radicals and peroxynitrite, thiol groups against oxidation induced by hydrogen peroxide, peroxyl radicals, hypochlorite and peroxynitrite, and erythrocytes against hemolysis induced by peroxyl radicals and hypochlorite. These results show that carnitine has a direct antioxidant action against physiologically relevant oxidants.
6

Evaluation of vitamin C and vitamin B6 influence on the level of carnitine in plasma of healthy adults

84%
Jankowska M., Horabik A., Rutkowski B., Ejsmont J., Lysiak-Szydlowska W.
Polish Journal of Environmental Studies
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2004
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tom 13
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nr Suppl.2, Part 1
Efficiency of L-carnitine endogenous biosynthesis in humans depends on the presence of cofactors of numerous enzymatic reactions. Among others, the role of cofactor is played by vitamin C and vitamin B6. The objective of our study was to evaluate the influence of vitamins C and B6 stores on plasma carnitine level in healthy humans. The examined group consisted of 52 healthy volunteers. Total (TC) and free (FC) carnitine, ascorbic acid (AA) in plasma and indices of vitamin B6 in plasma and in erythrocytes were determined. Mean TC was 52.2 ± 10.7 mmol/1 and FC 44.4 ± 9.5 mmol/1. Mean AA was 0.4 ± 0.3 mg/dl. In 40% of examined group AA levels were out of the reference range. B6 indices in plasma and erythrocytes were 1.21 ± 0.23 and 1.42 ± 0.33, respectively. Vitamin C and vitamin B6 did not influence carnitine plasma levels, that confirms the marginal role of endogenous biosynthesis in the carnitine balance in healthy subjects. Moreover, a significant distribution of vitamin C deficiency was found in the evaluated population.
7

The effect of culturistic training and oral supplementation with L-carnitine on sports results, body make-up, aerobic and anaerobic efficiency, lipids and anti-oxidative enzymes in blood

84%
Eberhardt A., Ziemlanski S., Siwinska-Golebiowska H., Drela N., Kruszewski M., Derentowicz P., Markiewicz K., Kepa G., Panczenko-Kresowska B., Wit B., Busko K., Wychowanski M., Szczypiorski P., Strupinska E., Janowicz J.
Żywienie Człowieka i Metabolizm
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2000
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tom 27
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nr 4
The aim of this work was to examine the effect of culturistic training and oral supplementation with L-carnitine on sports results, body make-up, aerobic and anaerobic efficiency, lipids and anti-oxidative enzymes in blood. The testing was conducted before and after a 5-week long culturistic training of young males. One of the groups, chosen at random, was administered L-carnitine in a dose recommended by the producer (11.5 mg for 1 kg of body mass), the other group received placebo. It was stated that oral supplementation with L-carnitine increased the training effects in the form of force growth and force endurance, other assayed parameters did not show significant differences.
8

Effects of chromium picolinate, L-carnitine and thyroxine on the performance, nutrient digestibility and nitrogen balance in pigs weaned at 21 days of age

84%
Cho W.T.Han I.K., Chae B. J., Han Y. K., Ha J. K., Odle J.
Journal of Animal and Feed Sciences
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2000
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tom 09
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nr 4
9

The effect of supplementing diet with L-carnitine on its levels in plasma and urine in individuals subjected to heavy work loads

84%
Raczynska B., Malczewska J., Raczynski G.
Polish Journal of Food and Nutrition Sciences
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2000
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tom 09/50
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nr 2
The aim of the study was (1) to determine changes in the total (TC), free (FC) and esterified (EC) L-carnitine (C) in plasma and urine of biathlonists ingesting various doses of C and (2) to find out whether the quantities of C ingested with the diet covered the metabolic needs for this compound. Male (n = 24) and female (n = 22) athletes, aged 17 years were divided in 4 groups given 0, 250, 500 and 750 mg-d"1 of C, respectively. The contents of energy, selected nutrients and of C were assessed by using the food composition tables. Relative C deficiency was determined from FC/TC and EC/FC ratios obtained from plasma measurements. The supplementation with C increased its concentration in plasma and excretion of FC and TC with urine, the levels of EC remaining relatively stable. Mean values of FC/TC and EC/FC ratios were within normal limits and did not depend on the degree of supplementation with C. However, relative C deficiency was observed in two men and five women and could have resulted from a too low C intake with diet or from an intensified catabolism of fatty acids. Supplementing athletes with small doses of C (250-500 mg·d-1) may thus be recommendable.
10

The effect of training on plasma L-carnitine metabolism in purebred Arabian horses

67%
Kedzierski W.
Journal of Animal and Feed Sciences
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2010
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tom 19
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nr 3
The aim of this study was to evaluate how training affects plasma total, free and esterified L-carnitine concentrations in horses. The study was done on a total of 32 healthy, trained purebred Arabian horses. The 32 horses comprised two groups. In the first group, 12 stallions and 6 mares three-year-old involved in race-training were studied at rest. In the second group, 14 stallions were studied during a typical race or endurance training session. Jugular venous blood samples were collected to determine lactic acid (LA), free fatty acids, glycerol, triacylglycerides (TG), and the total esterified and free L-carnitine contents. The race training session caused a significant increase in blood LA and plasma esterified L-carnitine, glycerol, and TG levels. It also caused a decrease in the plasma free L-carnitine concentration determined just after the end of exercise. Compared with endurance training, high-intensity racing exercise increased the plasma esterified L-carnitine concentration and decreased that of free L-carnitine according to training intensity.
11

The effect of culturistic training and oral supplementation with L-carnitine on the immune system

67%
Eberhardt A., Ziemlanski S., Siwinska-Golebiowska H., Drela N., Kruszewski M., Derentowicz P., Markiewicz K., Kepa G., Szczypiorski P., Strupinska E., Janowicz J.
Żywienie Człowieka i Metabolizm
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2000
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tom 27
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nr 4
The aim of this work was to test the effect of culturistic training and oral supplementation with L-carnitine on induced and spontaneous chemotaxis of granulocytes, chemiluminescence of granulocytes and intracellular expression of cytokines 11-2, IL-4, IFN-γ in lymphocytes. The tests were done before and after 5-week culturistic training of young males. One of the chosen at random groups received L-carnitine in a dose of 11.5 mg for 1 kg of body mass, the other one received placebo. It was stated that training increases spontaneous chemotaxis of granulocytes. Supplementation with L-carnitine only stimulated spontaneous chemotaxis of granulocytes derived from capillary blood, no significant differences were stated in other assays which points at a fact that L-carnitine administered in a dose of 11.5 mg for 1 kg of body mass through the period of 5 weeks does not produce unfavourable changes in the immune system of sportsmen and may exert immunomodulating influence.
12
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Suplementy diety w żywieniu uczniów szkoły mistrzostwa sportowego

51%
Seidler T., Sobczak A.
Roczniki Państwowego Zakładu Higieny
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2012
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tom 63
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nr 2
Wprowadzenie. Od pewnego czasu obserwuje się wzrost zainteresowania suplementacją diety. Problem dotyczy zwłaszcza sportowców i osób aktywnych fizycznie. Wynika to często z przekonania, że zwyczajowa dieta nie zapewnia właściwej podaży składników pokarmowych. Z suplementacją diety wiążą się jednak pewne zagrożenia, które nabierają szczególnego znaczenia w przypadku młodych sportowców, w tym uczniów szkół mistrzostwa sportowego. Cel badań. Celem badań była ocena stosowania suplementacji diety przez uczniów szkoły mistrzostwa sportowego w województwie zachodniopomorskim. Materiał i metody. Badania przeprowadzono w grupie 76 uczniów w wieku 15-19 lat, trenujących piłkę siatkową (dziewczęta n=39) oraz piłkę nożną (chłopcy n=37) w szkole mistrzostwa sportowego w Policach (woj. Zachodniopomorskie). W badaniach zastosowano metodę wywiadu. Określono istotność różnic w obrębie analizowanego czynnika w zależności od uprawianej dyscypliny sportowej przy pomocy testu Chi2 pakietu Statistica 9. Wyniki. Stwierdzono, że uczniowie szkoły mistrzostwa sportowego stosowali suplementację diety. Częściej występowała ona w grupie chłopców (67,6%) niż dziewcząt. Najbardziej popularnym suplementem w obu grupach był magnez (57- 64%). W dalszej kolejności były preparaty witaminowo-mineralne i L-karnityna. Stwierdzono istotne różnice pomiędzy dyscyplinami sportowymi co do przyczyn stosowania suplementacji diety oraz źródeł pozyskiwania informacji na temat suplementów. Wnioski. Suplementacja diety wśród badanych uczniów szkoły mistrzostwa sportowego w Policach była popularna, mimo że nie dokonano rozpoznania czy jest ona konieczna. Suplementy diety częściej spożywali piłkarze. Najchętniej jako suplement diety wybierano magnez. Zalecane byłoby systematyczne szkolenie sportowców z zakresu racjonalnego żywienia. Szkolenie powinno również objąć trenerów szkolących młodzież.
13

Sprawozdanie z konferencji - Napoje energetyzujace - aspekty zdrowotne i legislacyjne. Warszawa, Instytut Zywnosci i Zywienia, 26 maja 1999 rok

43%
Wierzejska R.
Żywność Żywienie Prawo a Zdrowie
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2000
|
tom 09
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nr 1
90-94
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