During 2004–2008 the influence of two herbicides: Maraton 375 SC (pendimethalin 250 g/l + isoproturon 125 g/l) and Carat 350 SC (diflufenikan 100 g/l + flurtamon 250 g/l) on yield and grain quality of winter wheat (Tonacja, Sukces, Trend, Kobiera, Kobra, Finezja) cultivars was examined. Maraton 375 SC was used at the dose 4.0 l/ha and Carat 350 SC at the dose 0.75 l/ha. Both herbicides were applied in the autumn, when wheat reached stage of 2–4 leaves. Examined herbicides did not influence negatively grain yield of winter wheat cultivars and grain parameters: protein and gluten content, falling number, weight of hectoliter and seed grading. Herbicide Maraton 375 SC significantly reduced sedimentation index of Sukces cultivar in comparison with untreated plots.