Wyniki wyszukiwania

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Heterogeneity of antibody response to mycobacterial antigens in different clinical manifestations of pulmonary tuberculosis

100%

Demkow U., Filewska M., Michalowska-Mitczuk D., Kus J., Jagodzinski J., Zielonka T., Zwolska Z., Wasik M., Rowinska-Zakrzewska E.

Journal of Physiology and Pharmacology. Supplement

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2007

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tom 58

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nr 5

2

Ocena powtarzalności oznaczania przeciwciał przeciwprątkowych anty-A60 metodą immunoenzymatyczną

100%

Demkow U., Zielonka T. M., Bialas-Chromiec B., Filewska M., Michalowska-Mitczuk D., Soszka A., Boros P., Augustynowicz-Kopec E., Kus J., Zwolska Z.

Diagnostyka Laboratoryjna

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2002

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tom 38

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nr 1

3

Zastosowanie testów immunoenzymatycznych wykrywających przeciwciała przeciwko antygenom prątka do diagnostyki gruźlicy

100%

Demkow U., Bialas B., Filewska M., Zielonka T., Michalowska-Mitczuk D., Kus J., Augustynowicz E., Zwolska Z., Skopinska-Rozewska E., Rowinska-Zakrzewska E.

Diagnostyka Laboratoryjna

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2004

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tom 40

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nr 3

4

Diagnostic value of different serological tests for tuberculosis in Poland

81%

Demkow U., Ziolkowski J., Filewska M., Bialas-Chromiec B., Zielonka T., Michalowska-Mitczuk D., Kus J., Augustynowicz E., Zwolska Z., Skopinska-Rozewska E., Rowinska-Zakrzewska E.

Journal of Physiology and Pharmacology. Supplement

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2004

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tom 55

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nr 3

57-66

The aim of the study was to test the diagnostic accuracy of several serological assays for the diagnosis of tuberculosis (TB) in the Polish population. ELISA based assays detecting: 38kDa+LAM - MycoM, MycoA and MycoG, 38kDa - Pathozyme TB complex, 38kDa+16kDa - Pathozyme TB complex plus were used. The humoral immune response was analyzed in a group of 319 TB patients (289 adults and 30 children) and in a control group consisting of 66 sarcoidosis cases, 16 cases of mycobacterial infections other than tuberculosis, 35 lung cancer patients, and 70 healthy volunteers. Among the TB patients, there were 267 cases of pulmonary TB and 52 cases of extrapulmonary TB. Sensitivity varied between 32% (IgM) and 63% (IgA) and increased in culture positive tuberculosis and in chronic cases. Specificity was the highest for the tests based on recombinant antibodies (98%). Sensitivity of the IgG test in extrapulmonary TB was comparable with that in pulmonary TB. Overall, sensitivity of the examined tests was lower in children than in adults, but it varied depending on the age and phase of the disease. We conclude that the ELISA-based tests may be a useful tool for improving the diagnosis of TB, especially in adults and in those countries where the prevalence of culture positive and chronic cases is high.

Ograniczanie wyników

2 Diagnostyka Laboratoryjna

2 Journal of Physiology and Pharmacology. Supplement

4 Demkow U.

4 Filewska M.

4 Kus J.

4 Michalowska-Mitczuk D.

4 Zwolska Z.

3 Rowinska-Zakrzewska E.

3 Zielonka T.

2 Augustynowicz E.

2 Bialas-Chromiec B.

2 Skopinska-Rozewska E.

1 Augustynowicz-Kopec E.

1 Bialas B.

1 Boros P.

1 Jagodzinski J.

1 Soszka A.

1 Wasik M.

1 Zielonka T. M.

1 Ziolkowski J.

1 2007

2 2004

1 2002

Heterogeneity of antibody response to mycobacterial antigens in different clinical manifestations of pulmonary tuberculosis

Ocena powtarzalności oznaczania przeciwciał przeciwprątkowych anty-A60 metodą immunoenzymatyczną

Zastosowanie testów immunoenzymatycznych wykrywających przeciwciała przeciwko antygenom prątka do diagnostyki gruźlicy

Diagnostic value of different serological tests for tuberculosis in Poland