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1

Pozycjonowanie produktu przy wykorzystaniu badan preferencyjnych

100%
Krawczynska A., Trzmielak D.
Przegląd Organizacji
|
2000
|
nr 09
36-38
2
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Content available

Effect of dietary fat type on plasma lipid profile and leptin concentration in rats fed on high-sucrose diets

81%
Krawczynska A., Okreglicka K., Olczak E., Gromadzka-Ostrowska J.
Journal of Pre-Clinical and Clinical Research
|
2010
|
tom 04
|
nr 1
3

Impact of cholesterol, vitamin E supplementation and dietary fatty acids on testis function in high-fat diet fed rats

80%
Jablonska O., Krawczynska A., Olczak E., Gromadzka-Ostrowska J.
Polish Journal of Food and Nutrition Sciences
|
2006
|
tom 15/56
|
nr Spec.Issue 2
The aim of the study was to determine whether consumption of diets containing different fat (rapeseed oil or lard-rich), supplemented with a high level of cholesterol (3% w/w) and/or vitamin E (500 mg/kg of diet) for 6 weeks influenced 17beta-hydroxysteroid dehydrogenase (17β-HSD) type 3 activity (measured in vitro), testosterone (Tt) content in testes and plasma testosterone (Tp) concentration (measured by ELISA and RIA, respectively) in male rats. 17β-HSD activity was shown to depend on dietary fat type. Supplementation of vitamin E influenced Tt value, whereas none of the investigated dietary factors had effects on Tp. Significant differences between the investigated factors were observed only for groups fed rapeseed oil-rich diets with marked increases of Tt and Tp in rats fed vitamin E-rich diet.
4

Jakosc uslug medycznych

80%
Krawczynska A., Trzmielak D.
Przegląd Organizacji
|
2001
|
nr 02
35-37
5

Rolnictwo Brazylii: nie tylko kawa.

80%
Krawczynska A.
Geografia w Szkole
|
1994
|
tom 47
|
nr 2
85-90
6
Content available remote

Time-dependent supplementation of vitamin E influences leptin expression in the aortic layers of rats fed atherogenic diet

71%
Krawczynska A., Olczak E., Rembiszewska A., Herman A. P., Gromadzka-Ostrowska J.
Journal of Physiology and Pharmacology
|
2014
|
tom 65
|
nr 1
7

The effect of repeated endotoxin injection on gonadotropin secretion in ewes

71%
Herman A. P., Kopycinska K., Krawczynska A., Romanowicz K., Tomaszewska-Zaremba D.
Journal of Animal and Feed Sciences
|
2014
|
tom 23
|
nr 3
Although it is well known that acute inflammation induced by a single injection of the bacterial endotoxin, lipopolysaccharide (LPS), induces a stress response and suppresses luteinizing hormone (LH) secretion, the effects of repeated endotoxin administration on gonadotropin secretion in sheep have not been studied yet. In this work, the influence of inflammation induced by six days of intravenous LPS injection (400 ng· kg–1 per day) on the release of LH and follicle-stimulating (FSH) hormones was evaluated. Anoestrous ewes were bled twice a day 1 h before and 3 h after LPS injection. Endotoxin injection decreased (P < 0.05) the release of LH from the first day of the experiment. Moreover, on day 5, the suppression of LH secretion was sustained and could also be detected in the samples collected before the next LPS injection. In contrast, elevation (P < 0.05) of FSH release was detected starting from the second dose of the endotoxin. The increased FSH concentration persisted until the end of the experiment. Each LPS injection stimulated (P < 0.05) cortisol release, but from days 3 to 6, this elevation was about three times lower than the level determined during the first two days. The obtained results show that ewes exposed to repeated administration of endotoxin lost their ability to restore proper LH release relatively quickly. This disturbance in gonadotropin secretion could, in part, be associated with the stress induced by LPS, as well as with endotoxin-induced inflammatory challenges.
8

Photoperiodic conditions as a factor modulating leptin influence on pro-inflammatory cytokines and their receptors gene expression in ewe’s aorta

61%
Krawczynska A., Antushevich H., Bochenek J., Wojtulewicz K., Pawlina B., Herman A. P., Zieba D. A.
Journal of Animal and Feed Sciences
|
2019
|
tom 28
|
nr 2
Atherosclerosis, a chronic inflammation state of the aorta, is characterised by increased levels of pro-inflammatory cytokines (tumour necrosis factor alpha (TNFα), interleukin (IL)-1β, IL-6). Sheep is used in both cardiovascular and immunological studies; besides, ‘long-day’ ewe can be a model of leptin resistance state. The aim of the study was to examine whether photoperiodic conditions (long-day (LD) and short-day (SD) seasons) are a key factor modulating exogenous leptin influence on pro-inflammatory cytokines and their receptors gene expression in aorta of ewe’s with or without prior induction of acute inflammation. The experiment was conducted on 48 ewes during SD and LD seasons which were randomly divided into 4 groups: control; with LPS injection (400 ng/kg of body weight (BW)); with leptin injection (20 μg/kg BW); and with LPS and 30-min later leptin injection. Three hours after LPS/control treatment animals were euthanized to collect the thoracic aorta samples. In both seasons leptin injection intensified LPS-induced increase in IL1B gene expression but only in SD season leptin injection increased IL1R1 and IL1R2 gene expressions. The leptin injection increased IL6 gene expression but only in SD season. In the LD season leptin enhanced the LPS effect on IL6 gene expression. Neither TNFA nor its receptors gene expression was influenced by leptin regardless of season. In the thoracic aorta tissue an exogenous leptin exerts effect on pro-inflammatory cytokines and their receptors gene expression; however in ewe this influence depends on photoperiodic conditions. Moreover, leptin can moderate progression of the inflammation reaction in this tissue.
9
Content available remote

The role of apelin in the modulation of gastric and pancreatic enzymes activity in adult rats

61%
Antushevich H., Kapica M., Krawczynska A., Herman A., Kato I., Kuwahara A., Zabielski R.
Journal of Physiology and Pharmacology
|
2016
|
tom 67
|
nr 3
10

The effect of breed and feeding level on carcass composition, fatty acid profile and expression of genes encoding enzymes involved in fat metabolism in two muscles of pigs fed a diet enriched in n-3 fatty acids. A preliminary study

61%
Sobol M., Krawczynska A., Skiba G., Raj S., Weremko D., Herman A. P.
Journal of Animal and Feed Sciences
|
2015
|
tom 24
|
nr 1
The experiment was performed according to a 2 x 2 factorial design with breed and level of nutrition as factors affecting fat metabolism in pigs. Two groups of gilts, each comprising 4 Polish Large White (PLW) and 4 Synthetic Line 990 (L990) animals, were fed from 60 to 105 kg body weight on the experimental diet at 85% or 95% of assumed ad libitum intake. The diet contained 2% of linseed, 0.5% rapeseed and 0.5% fish oils as the source of n-3 fatty acids (FA). The carcass protein content was smaller and backfat thickness greater in L990 than in PLW pigs. Also the intramuscular fat content in the biceps femoris (BF) and longissimus dorsi (LD) muscles and their contents of total FA, saturated fatty acids, monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA) were higher or tended to be higher in L990 than in PLW pigs, the differences between the breeds being more pronounced in the BF muscle. The n-6/n-3 PUFA ratio tended to be lower in the LD muscle, whereas in the BF muscle, it was lower in L990 than in PLW pigs. Feeding at the 85% level resulted in smaller backfat thickness and carcass fat content in animals of both breeds. Gene expression of stearoyl-CoA desaturase in both muscles was higher in L990 pigs, which could have resulted in the higher MUFA and PUFA contents in this breed. Gene expression of fatty acid-binding protein 4 and peroxisome proliferator-activated receptor were affected both by breed and feeding level only in the BF muscle.
11

Caffeine stimulates in vitro pituitary LH secretion in lipopolysaccharide-treated ewes

61%
Herman A. P., Herman A., Skipor J., Krawczynska A., Bochenek J., Tomaszewska-Zaremba D.
Reproductive Biology
|
2015
|
tom 15
|
nr 1
12

Photoperiod alters the choroid plexus response to LPS-induced acute inflammation in ewes

61%
Skipor J., Szczepkowska A., Kowalewska M., Domzalska M., Herman A. P., Krawczynska A.
Annals of Animal Science
|
2021
|
tom 21
|
nr 2
13

Ruminal degradability of Virginia fanpetals (Sida hermaphrodita) herbage and silage depending on the harvest time

61%
Michalski J. P., Borsuk M., Nogalski Z., Baranowska M., Krawczynska A., Purwin C.
Journal of Animal and Feed Sciences
|
2020
|
tom 29
|
nr 4
14
Content available remote

Influence of fundectomy and intraperitoneal or intragastric administration of apelin on apoptosis, mitosis, and DNA repair enzyme OGG1,2 expression in adult rats gastrointestinal tract and pancreas

51%
Antushevich H., Pawlina B., Kapica M., Krawczynska A., Herman A. P., Kuwahara A., Kato I., Zabielski R.
Journal of Physiology and Pharmacology
|
2013
|
tom 64
|
nr 4
15

The apelin-13 influences the activity of pancreatic enzymes in young rats

51%
Antushevich H., Kapica M., Kuwahara A., Kato I., Krawczynska A., Herman A. P., Pawlina P., Zabielski R.
Journal of Animal and Feed Sciences
|
2016
|
tom 25
|
nr 2
Apelin and its APJ receptor are present inter alia in colostrum and in the young animal gastrointestinal tract. This peptide exerts numerous effects participating in the appetite and drinking behaviour, gastric acid and insulin secretion. The aim of the study was to investigate the effect of apelin-13 on the activity of pancreatic and gastric enzymes in young animals. The two experiments were carried out on weaning Wistar rats (50 ± 10 g) which received the apelin-13 or physiological saline (in the corresponding control groups) by intragastric or intraperitoneal way twice a day for 10 days (100 nmol · kg–1 body weight). At the end of each experiment rats were sacrificed and blood samples were collected for apelin and cholecystokinin (CCK) radioimmunoassay. The fragments of the pancreas and stomach were weighted and frozen for the further digestive enzymes activity analysis. The intragastric and intraperitoneal administration of apelin-13 increased plasma CCK level in young rats. The intraperitoneal injection of apelin-13 stimulated pancreatic trypsin, -amylase and lipase activity, but had no effect on the activity of gastric enzymes. On the other hand, the intragastric administration of apelin-13 stimulated only the activity of pancreatic lipase and had no effect on the activity of gastric pepsin and rennet. So, circulating apelin exerts the most pronounced effect on pancreatic enzymes activity in young rats, but neither circulating nor luminal apelin influences gastric enzymes activity. Regardless the route of administration, apelin stimulates lipase activity which points out its considerable role in the regulation of the fat digestion.
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