Wyniki wyszukiwania

1

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Life-threatening conditions in psychiatry - neuroleptic malignant syndrome (NMS)

100%

Kucmin T., Kucmin A., Plowas-Goral M., Jojczuk M.

Journal of Pre-Clinical and Clinical Research

|

2015

|

tom 09

|

nr 1

The introduction of neuroleptics in the 1950’s was a turning point in psychiatric treatment. The new drugs brought hope to millions of patients and their doctors. However, there were also some side-effects, one of which is Neuroleptic malignant syndrome (NMS), a rare complication of antipsychotic treatment and untreated it may lead to mortality as high as 20%. The incidence of NMS, estimated to be 0.01–0.02%, has decreased significantly probably due to higher awareness of the diseases and shift to atypical antipsychotics. The aim of this study was to present the signs and symptoms of this rare condition and describe management possibilities since this condition is observed not only in psychiatric departments but also in emergency rooms. NMS is thought to be related to change caused by neuroleptics within the central nervous system due to dopamine D2 receptor antagonism, especially nigrostriatal pathways and the hypothalamus. There are three symptoms which are considered as major and indicate a high probability of NMS: muscle rigidity, hyperthermia (core body temperature above 38.5 °C), and elevated creatine phosphokinase concentration (above 1000 U/l). NMS is a diagnosis of exclusion and clinicians must be vigilant in detecting early signs of NMS. The basic management in NMS is antipsychotic discontinuation and proper supportive care of the patient (vital signs monitoring, hydration, correction of electrolyte and acid-base disturbances). In more severe cases, the introduction of bromocriptine or dantrolene, as well as benzodiazepines, may indicated. Further usage of neuroleptic in patients with a history of NMS should be with care, and low doses of low-potency neuroleptics or atypical neuroleptics seem to be the best treatment choice.

2

Mortality prediction by ‘Life Threat Index’ compared to widely used trauma scoring systems

100%

Jojczuk M., Nogalski A., Krakowski P., Prystupa A.

Annals of Agricultural and Environmental Medicine

|

2022

|

tom 29

|

nr 2

3

Lower limb wounds caused by dog bites

76%

Flisiuk M., Karska A., Lubek T., Jojczuk M., Podlewski J., Karski J., Nogalski A.

Bulletin of the Veterinary Institute in Puławy

|

2010

|

tom 54

|

nr 1

113-116

Four patients, with an average age of 58 years, hospitalised in 2008 because of bite wounds to the lower leg, were analysed. The study was based on the analysis of medical records and the results of laboratory and microbiological tests. Precise wound cleansing and dressing, appropriate to each case, are principal elements of management in the treatment of dog bite wounds. Potential complications include limb infection, deformation, and amputation.

4

Treatment of lower limb trophic ulcers using hyperbaric oxygenation

76%

Kulesza T., Mitrut T., Jojczuk M., Jaholkowski L., Nodalski A., Prystupa A.

Journal of Pre-Clinical and Clinical Research

|

2014

|

tom 08

|

nr 1

5

Blunt abdominal trauma from horse kicks

76%

Lubek T., Kulesza T., Jojczuk M., Ochali A., Olszewski G., Prystupa A., Nogalski A.

Journal of Pre-Clinical and Clinical Research

|

2013

|

tom 07

|

nr 1

6

Use of neural network based on international classification ICD-10 in patients with head and neck injuries in Lublin Province, Poland, between 2006–2018, as a predictive value of the outcomes of injury sustained

64%

Jojczuk M., Kaminski P., Gajewski J., Karpinski R., Krakowski P., Jonak J., Nogalski A., Gluchowski D.

Annals of Agricultural and Environmental Medicine

|

2023

|

tom 30

|

nr 2

7

Large plexiform neurofibroma on right thigh of a farmer in the course of Recklinghausen disease - Case report

52%

Sompor J., Prystupa A., Wawrzycki B., Wojciechowska K., Kancik E., Kurys-Denis E., Ochal A., Prystupa T., Jojczuk M., Kulesza T., Antosz H.

Journal of Pre-Clinical and Clinical Research

|

2014

|

tom 08

|

nr 2

A 59-year-old farmer was admitted to the Department of Trauma Surgery because of pain associated with the presence of a tumour on the side of the right thigh. The patient stated that his biggest problem was great difficulty in moving and handling agricultural machinery due to the aforementioned lesion. On physical examination, the patient presented with numerous cutaneous and subcutaneous neurofibromas, as well as one large plexiform neurofibroma. Diagnosis of Neurofibromatosis type 1 was established, based on National Institutes of Health diagnostic criteria. Moreover, molecular genetic testing found known pathogenic mutation p.Arg1769* in one of the alleles of NF1 gene (heterozygote), typical for Recklinghausen disease. The big plexiform neurofibroma in the patient was not operated on because of lung cancer.

Ograniczanie wyników

Life-threatening conditions in psychiatry - neuroleptic malignant syndrome (NMS)

Mortality prediction by ‘Life Threat Index’ compared to widely used trauma scoring systems

Lower limb wounds caused by dog bites

Treatment of lower limb trophic ulcers using hyperbaric oxygenation

Blunt abdominal trauma from horse kicks

Use of neural network based on international classification ICD-10 in patients with head and neck injuries in Lublin Province, Poland, between 2006–2018, as a predictive value of the outcomes of injury sustained

Large plexiform neurofibroma on right thigh of a farmer in the course of Recklinghausen disease - Case report