Wyniki wyszukiwania

1

Współczesna rodzina jako środowisko wychowawcze (socjalizacyjno-enkulturacyjne)

100%

Majorczyk M.

Scripta Comeniana Lesnensia. Seria A. Miscellanea. Państwowa Wyższa Szkoła Zawodowa im.Jana Amosa Komeńskiego w Lesznie

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2010

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nr 08

2

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Effect of physical activity on IGF-1 and IGFBP levels in the context of civilization diseases prevention

63%

Majorczyk M., Smolag D.

Roczniki Państwowego Zakładu Higieny

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2016

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tom 67

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nr 2

Background. Insulin-like growth factor 1 (IGF-1) is known as somatomedin C. This polypeptide hormone is functionally and structurally similar to insulin. IGF-1 effects on tissue by the IGF-1R and the insulin-like growth factor-binding protein also known as IGFBP. Abnormal IGF-1 and IGFBP signaling are positively correlated with a high risk of selected civilization diseases development. Physical inactivity is a one of the main causes of majority of chronic diseases and it is associated with eg. IGF-1 and IGFBPs level. Objective. The aim of the study was to explanation the effect of physical activity on IGF-1 and its binding protein – IGFBPs concentration in the context of selected civilization diseases prevention. The review of clinical trial. Material and Methods. The review of articles had published in databases: MEDLINE, EMBASE, Scopus and Web of Science until December 2015. The selected prospective studies about the effect of exercise on IGF-1 level and its binding protein IGFBP in the context of selected civilization diseases prevention were collected. Results. The majority of the included studies indicate that mechanical loading is a key mechanism linking IGF-1/IGFBPs concentration and selected chronic diseases development. The duration and intensity of physical activity have a significant impact on IGF-1 and IGFBP serum. The highest concentration of IGF-1 in serum was after eccentric training. “Overtraining” increases unfavorable and unbound IGF-1 levels and contributes to the increased incidence of hormone-cancer and osteoarthritis. Conclusions. Irregularity of the GH/IGF-1 axis may affect on the development of rheumatic diseases, cardiovascular diseases (regulate cardiac growth and metabolism) and metabolic syndrome.

3

Criteria for selecting attributes for the prognostic neural model based on limited data set

51%

Janaszak M., Majorczyk M., Mankowski D. R., Trajer J.

Annals of Warsaw University of Life Sciences - SGGW. Agriculture

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2007

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nr 51 Agric.Forest Eng.

99-104

Ograniczanie wyników

1 Annals of Warsaw University of Life Sciences - SGGW. Agriculture

1 Roczniki Państwowego Zakładu Higieny

1 Scripta Comeniana Lesnensia. Seria A. Miscellanea. Państwowa Wyższa Szkoła Zawodowa im.Jana Amosa Komeńskiego w Lesznie

3 Majorczyk M.

1 Janaszak M.

1 Mankowski D. R.

1 Smolag D.

1 Trajer J.

1 2016

1 2010

1 2007

Współczesna rodzina jako środowisko wychowawcze (socjalizacyjno-enkulturacyjne)

Effect of physical activity on IGF-1 and IGFBP levels in the context of civilization diseases prevention

Criteria for selecting attributes for the prognostic neural model based on limited data set