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Pregnant women (139) were followed-up prior to the preventive treatment. Among them 76 (54.8%) had abortions, 20 (14.3%) - premature and 43 (14.3%) - normal labour. Among the born babies, 9 were alive, 13 had congenital (23.9%) and 21 were still born. In 69 pregnant women daraprim was given in the dosis of 675 mg per one therapeutic course, dosulphine in 18 g, or orisol in 12 g per one therapeutic course for 21 or 25 days. The treatment was applied between the 2nd and 4th and the 6th-8th month of pregnancy. In 58 women (84.0%) subjected to the treatment the labour was normal; 53 of them (91.3%) were delivered of healthy babies, 4 (6.8%) of still born ones, and one woman (1.7%) gave birth to a mentally deficient child. There were 2 cases of premature labour and 4 abortions. In 49 women (81.8%), the complement fixation and intracutaneous tests gave positive results in 36.6%.
Mice were infected with RH Toxoplasma gondii by intraperitoneal injection of 0.4 ml of protozoa containing exudate; the drugs were administered by oral or intraperitoneal route for 10 days after the infection, the survival rate of animals constituting a criterion of efficiency. Among the applied drugs, daraprim proved to be the most efficient, since given in the doses of 0.025-0.5 daily it was found to increase the survival time by 3-30 days; supronal in the dosis of 10.0-13.3 mg caused an increase by 15-16 days, and orisol in 1.5-2.0 mg prolonged the survival rate only by 4 days. Far better results were obtained with the combination of 2 drugs. The strongest action was exerted by daraprim and dosulphin (0.025 mg + 1.5 mg) increased the survival rate by 56 days, then dosulphin and orisol (1.5 mg + 2.0 mg), dosulphin and supronal (1.5 mg + 10.0 mg) and daraprim and supronal (0.025 mg + 10.0 mg) resulting in a 37-day increase. Less efficient were orisol + supronal (21-day increase) and daraprim + orisol (by 23 days).
The aim of this work was to determine the role of toxoplasmosis in the pathology of pregnancy among women in the Lublin province, and simultaneously the attempt to evaluate the correlation between three diagnostic methods: Frenkel's intradermal test, Sabin-Feldman's dye test and complement fixation reaction. 396 women were examined and 332 simultaneously submitted to serological and allergical investigations. In 64 cases the investigations were only carried out with the complement fixation and intradermal tests. The highest number of positive results was obtained by the intradernal reaction, i. e. 33.8%, the lowest by the complement fixation reaction 8.3%. The dye test gave 10.6%. The conformity of the results for all three tests amounts to 56.7% (225 cases). In the remaining cases (171) the conformity of results between the individual tests was studied, and so: for the complement fixation and the dye tests it amounted to 15.6%, for complement fixation and Frenkel's intradermal tests to 12.5%, for the dye test and Frenkel's intradermal test - 6.7%. The remaining 9,5% fell on the unconformity between the results of the complement fixation reaction and Frenkel's intradermal test. The highest percentage of infections has been observed in the group of premature deliveries; that is 56.6%. To this group belongs also a relatively great number of stillborn children and children with development defects. In the group of women who suffered abortion the percentage of positive results is the lowest – 21.05%. The percentage of positive results is almost identical in the goup of women who were not suspected of toxoplasmosis and in the group where this suspicion existed (32.1%-34,7%). An exact anamnesis concerning the pregnancies of 241 women (multiparae) has shown that the number of abortions in the group of women with positive results is by 50% higher than in the group with negative results. The number of nonviable fetuses is by 2.9 times higher and the number of premature deliveries by 30% higher. The number of infants with development defects is 3 times higher in the group of women who were infected with toxoplasmosis. The number, however, of stillborn children with positive results amounts to 3,8%, while in the group of women with negative results to 5.6%. In cases of habitual abortion, premature delivery or development defects the possibility of toxoplasma infection in the mother should be taken into consideration and laboratorial investigations carried out, such as: complement fixation reaction, Sabin-Feldman's dye test and Ftenkel's intradermal test. A positive results of even one of the serological test in comparison with clinical observations makes an anti-toxoplasmosis treatment unavoidable.
Occurrence of Chimaphila umbellata (Ericaceae) in central eastern Poland. Fragmenta Floristica et Geobotanica Polonica 8: 113–119. Kraków. PL ISSN 1640 629X. ABSTRACT: The list of 180 stations of Chimaphila umbellata (L.) W. P. C. Barton in eastern central Poland is given in the paper. The most numerous stations have been found in the Puszcza Biała Forest (Międzyrzecze Łomżyńskie), in Bug river valley (Podlaski Przełom Bugu) and in Siedlce environs (Wysoczyzna Siedlecka). It is the result of domination of coniferous forests in this areas and accuracy of area examination. The preliminary data on ecology of population of Ch. umbellata in range Niwiski near Siedlce are also given.
Cymbalaria muralis is a rare kenophyte occurring on brick and stone walls. The species is known from 157 localities situated mainly in western part of Poland. Stands of the species usually are not found to the East of Vistula river. A new locality of the species was found in the area of the historic manor house in Bachorza (Łosice district, Mazowsze Province). It is the furthest to the east locality of the species in Poland. The stand of Cymbalaria muralis covers an area of about 12 square meters in various habitat conditions. Regarding differences in humidity and insolation of the particular surfaces, 20 shoots have been investigated while alive. The stem length was measured and the number of leaves and flowers of particular shoots were counted. The results of the present study indicate that the most important features of Cymbalaria muralis stand in Bachorza are humidity and insolation intensity.
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