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1

Role of the unfolded protein response in the pathogenesis of Parkinson’s disease

100%
Varma D., Sen D.
Acta Neurobiologiae Experimentalis
|
2015
|
tom 75
|
nr 1
Parkinson's disease is the second most common neurodegenerative disease which affects almost 1% of the population above the age of 60. It is is characterized by loss of dopaminergic neurons in the striatum and substantia nigra, coupled with the formation of intracellular Lewy bodies in degenerating neurons. Recent evidence suggests endoplasmic reticulum stress as a common and prominent occurrence in the progression of Parkinson's disease pathogenesis in the affected human brain. One of the cellular defense mechanism to combat endoplasmic reticulum stress due to excessive protein accumulation is through activation of the unfolded protein response pathway. In this review we focus on the impact and role of this unfolded protein response as a causative factor of Parkinson's disease leading to neurodegeneration.
2

Relationships between fish length and otolith length in the population of Capoeta capoeta umbla [Heckel, 1843] inhabiting Hazar Lake, Elazig, Turkey

80%
Sen D., Aydin R., Calta M.
Archives of Polish Fisheries
|
2001
|
tom 09
|
nr 2
In this study, the relationships between otolith length and fish length (total, fork and standard) of a total of 251 specimens of the Capoeta capoeta umbla (Heckel, 1843) (Cyprinidae) species inhabiting Hazar Lake were examined.The otolith lengths were measured for the whole otolith (in an anterior to posterior direction) by using an ocular microscope with a micrometer.There was a strong relationship between the otolith lengths and fish lengths obtained.
3

Age and growth of Capoeta trutta [Pisces: Cyprinidae] from Keban Dam Lake, Turkey

80%
Aydin R., Calta M., Sen D.
Archives of Polish Fisheries
|
2003
|
tom 11
|
nr 2
In this study the ages of Capoeta trutta (Heckel 1843) inhabiting Keban Dam Lake were determined from scales. The mean fork lengths determined using the back-calculation method were l₁=70.59, l₂=119.37, l₃=167.53, l₄=195.97, l₅=221.03, l₆=250.52, l₇=274.63 and l₈=300.38 mm for males, l₁=68.87, l₂ =117.03, l₃=166.34, l₄=203.91, l₅=230.17, l₆=248.20, l₇=267.98 and l₈=294.69 mm for females, l₁=63.45, l₂=105.92, l₃=151.54, l₄=188.20, l₅=212.33, l₆=245.05, l₇=270.85 and l₈=295.97 mm for all fish samples. The calculated length of any of the age groups was always smaller than the real length measured for the same age group. The gap between calculated and measured lengths increased when the scales of older fish were used in the calculations.
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