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1

Larval toxocarosis in mice: immunoreactivity after multiple high dose infections

100%
Aldawek A. M., Levkut M., Revajova V., Dvoroznakova E.
Acta Parasitologica
|
2002
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tom 47
|
nr 3
Immunological responses of mice to threefold infection with infective Toxocara canis were studied up to 42 days. Mice of the experimental group were infected orally with 1000 infective eggs on days 0, 12, and 20 of the experiment (a total of 3000 eggs/mouse). The proliferative activity of spleen lymphocytes, production of specific antibodies in the serum, leukocyte counts, and T cells subpopulations in the blood and spleens were examined. The spleen T cells were significantly inhibited to 21 day post infection (dpi) while B cells were stimulated. An increased level of specific antibodies persisted almost the whole experiment. Leukocytosis with a dominant lymphocytosis was evident. In the peripheral blood the number of both CD8⁺ and CD4⁺ cells was significantly increased. Contradictory, a significant increase of the spleen CD8⁺ cells with a significant decrease of CD4⁺ cells was observed. In conclusion, the multiple high dose infection resulted in variable changes in the immune effector mechanisms. Some components were stimulated while others were inhibited which may suggest that immunosuppression is not the only major outcome of larval toxocarosis.
2

Histiocytic Ulcerative Gastroenterocolitis and Dermatoneoplasm in Boxer Dog - Clinical Case Report

100%
Kozak M., Levkut M., Revajova V., Magic D.
Medycyna Weterynaryjna
|
2003
|
tom 59
|
nr 12
3
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Distribution of CD4 and CD8 T cells in the small intestine of mice after probiotic treatment and Trichinella spiralis infection

88%
Dvoroznakova E., Buckova B., Hurnikova Z., Revajova V., Laukova A.
Annals of Parasitology
|
2016
|
tom 62
|
nr Suppl.
4

Mast cells and eosinophils in rat mammary gland tumours induced by N-Nitroso-N-methylurea

88%
Kissova V., Sevcikova Z., Revajova V., Herich R., Levkut M.
Bulletin of the Veterinary Institute in Puławy
|
2015
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tom 59
|
nr 3
The aim of the study was to evaluate the distribution and number of mast cells and eosinophils in rat mammary gland tumours induced by N-Nitroso-N-methylurea. The highest density of mast cells was found in cystic papillary adenocarcinomas of grade II. Eosinophils were detected only in the cystic papillary adenocarcinoma of grades I and II, in non-invasive cribriform adenocarcinoma and comedo-type carcinoma. Mast cell populations were observed perivascularly in the tumour stroma, in the host tumour interface, as well as in necrotic areas of neoplasms. Mast cells were observed to be intact according to their morphological changes, collectively referred to as degranulation. The obtained results indicate that mast cells and eosinophils play an important role in tumour micro-environment formation. The increased density of these cells in experimentally-induced rat mammary gland tumours suggests a poor prognosis in these cancers. Our results also confirmed that rat mammary gland tumours are good models for the study of breast cancers.
5

Immunosuppressive effect of Encephalitozoon cuniculi

88%
Valencakova A., Revajova V., Balent P., Lesnik F., Levkut M.
Bulletin of the Veterinary Institute in Puławy
|
2003
|
tom 47
|
nr 1
6

Changes in integrin-positive cells and T cell subpopulations in the peripheral blood and intestine of calves fed soya protein

76%
Brna M., Revajova V., Zitnan R., Levkut,Jr. M., Baran M., Levkut M.
Journal of Animal and Feed Sciences
|
2010
|
tom 19
|
nr 3
In order to examine the relation of known intestinal lesions to changes in T-cell phenotypes and integrin expression, 16 male 10-day-old Holstein calves were divided into two groups. For 28 days of the experiment, eight males were fed NutriMilk in which 50% of the crude protein was soya protein, and eight control animals, with NutriMilk containing only milk casein. The animals fed soya protein showed shorter jejunal villi with a corrugated surface and deeper crypts compared with the control calves. A higher density of CD8+ cells in the intestinal mucosa and a decrease of these cells in peripheral blood were found in calves fed soya protein. The number of CD11b-positive cells was decreased in the peripheral blood of calves fed soya protein. Lower expression of integrin could be related to the appearance of non-mature polymorphonuclear cells. It is not clear if the decrease in CD11b expression on blood cells could also be influenced by milk replacer, i.e. soya protein.
7

Effect of Enterococcus faecium EF 55 on morphometry and proliferative activity of intestinal mucosa in broilers infected with Salmonella Enteritidis

76%
Sevcikova Z., Blanar J., Laukova A., Revajova V., Strompfova V., Levkut M.
Journal of Veterinary Research
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2016
|
tom 60
|
nr 3
8

Polymerase chain reaction detection of caecal bacteria in case of preventive application of Enterococcus faecium EK13 against Salmonella enterica subsp. Enteritidis in chickens

76%
Herich R., Laukova A., Strompfova V., Revajova V., Levkut M., Pistl J.
Journal of Animal and Feed Sciences
|
2005
|
tom 14
|
nr 1
9

Influence of subchronic exposure to fungicide tolylfluanid on humoral and cell-mediated immune parameters in sheep immunized with Coxiella vaccine

64%
Kovalkovicova N., Pistl J., Elias D., Jackova A., Novotny J., Hlincikova S., Legath J., Revajova V., Kovac G.
Bulletin of the Veterinary Institute in Puławy
|
2005
|
tom 49
|
nr 3
10

Eimeria colchici and immunocompetent cells in specific and non-specific hosts

64%
Goldova M., Revajova V., Pistl J., Letkova V., Levkut M., Wagshal E., Csizsmarova G., Looszova A.
Acta Parasitologica
|
2001
|
tom 46
|
nr 1
11

Influence of Encephalitozoon cuniculi experimental infection on antirabies immunity in a mouse model

52%
Franka R., Svrcek S., Suli J., Benisek Z., Madar M., Hipikova V., Levkutova M., Zavadova J., Ondrejkova A., Ondrejka R., Levkut M., Revajova V.
Bulletin of the Veterinary Institute in Puławy
|
2006
|
tom 50
|
nr 3
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