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Expression of p16 (INK4a), cytokeratin 19, and Ki-67 in canine laryngeal squamous cell carcinoma

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Gandefer-Gola M., Ciaputa R., Nowak M., Madej J. A.

Bulletin of the Veterinary Institute in Puławy

2013

tom 57

nr 3

The study aimed at morphological and immunohistochemical characteristics of laryngeal squamous cell carcinomas and their metastases in canine lymph nodes and lungs. Tissue sections were stained using classical technique with haematoxylin and eosin. In addition, immunohistochemical studies were performed with p16, cytokeratin, and Ki-67 antibodies. An expression of all examined antigens was detected in laryngeal tumours, while in tumour metastases only expression of p16 protein and cytokeratin was demonstrated. The results pointed to higher proliferative potential of the primary tumour than of their metastases.

Ograniczanie wyników

1 Bulletin of the Veterinary Institute in Puławy

1 Ciaputa R.

1 Gandefer-Gola M.

1 Madej J. A.

1 Nowak M.

1 2013

Wyniki wyszukiwania

Expression of p16 (INK4a), cytokeratin 19, and Ki-67 in canine laryngeal squamous cell carcinoma