Wyniki wyszukiwania

1

HIF-1 expression in retinal ganglion cells and optic nerve axons in glaucoma

100%

Reszec J., Zalewska R., Bernaczyk P., Chyczewski L.

Folia Histochemica et Cytobiologica

|

2012

|

tom 50

|

nr 3

2

Assessment of inflammatory infiltration and angiogenesis in the thrombus and the wall of abdominal aortic aneurysms on the basis of histological parameters and computed tomography angiography study

88%

Lukasiewicz A., Reszec J., Kowalewski R., Chyczewski L., Lebkowska U.

Folia Histochemica et Cytobiologica

|

2012

|

tom 50

|

nr 4

3

Wirus brodawczaka ludzkiego a proces apoptozy.

88%

Reszec J., Sulkowska M., Guzinska-Ustymowicz K., Zalewska R., Sulkowski S.

Postępy Biologii Komórki

|

2003

|

tom 30

|

nr 2

311-323

4

Is littoral cell angioma of the spleen as rare as previously believed in the pediatric population?

88%

Matuszczak E., Reszec J., Debek W., Hermanowicz A., Chyczewski L.

Folia Histochemica et Cytobiologica

|

2012

|

tom 50

|

nr 3

5

AgNOR, Ki-67 and PCNA expression in fibroepithelial tumours of the breast in correlation with morphological features

88%

Barwijuk-Machala M., Musiatowicz B., Cylwik J., Reszec J., Augustynowicz A.

Folia Morphologica

|

2004

|

tom 63

|

nr 1

The authors retrospectively reviewed the cytological slides of 44 histopathologically confirmed fibroepithelial lesions of the breast, of which 11 were fibroadenoma (FA), 19 benign phyllodes tumours (PTLGM), 8 borderline (PTBM) and 6 malignant (PTHGM). The 2 FA misdiagnosed as PTLGM in cytological smears were both of cellular type. NORS were quantified in a series of the above cases using the silver-colloid method. Expression of Ki-67 and PCNA were evaluated by immunohistochemistry on sections from the corresponding paraffin blocks. The results were compared with morphological parameters. In phyllodes tumours (PT), the AgNOR scores showed a tendency to increase with degrees of malignancy. There was significant correlation between AgNOR counts and proliferation rates as determined by Ki-67 and PCNA immunostaining. Ki-67 and PCNA expression correlated with mitotic count, stromal overgrowth, cellularity and atypia in PT. Determination of the AgNOR number per cell revealed an overlap between FA and PTLGM. The proliferating activity determined by immunohistochemistry with Ki-67 and PCNA antibodies did not reveal any significant difference between FA and PTLGM. In summary, Ki-67 and PCNA expression is suggested as a marker of stromal element proliferation. The results obtained confirm the diagnostic difficulties in distinguishing PTLGM from FA of the cellular type using fine needle aspiration cytology.

6

Mast cells evaluation in meningioma of various grades

76%

Reszec J., Hermanowicz A., Kochanowicz J., Turek G., Mariak Z., Chyczewski L.

Folia Histochemica et Cytobiologica

|

2012

|

tom 50

|

nr 4

7

The evaluation of human papillomavirus and p53 gene mutation in benign and malignant conjunctiva and eyelid lesions

76%

Reszec J., Zalewska R., Pepinski W., Skawronska M., Bernaczyk P., Chyczewski L.

Folia Histochemica et Cytobiologica

|

2010

|

tom 48

|

nr 4

8

The influence of doxycycline on articular cartilage in experimental osteoarthrosis induced by iodoacetate

76%

Cylwik J., Kita K., Barwijuk-Machala M., Reszec J., Klimiuk P., Sierakowski S., Sulkowski S.

Folia Morphologica

|

2004

|

tom 63

|

nr 2

The experiment was performed on 36 Wistar rats. On the first day of the experiment iodoacetate was administered to the left posterior knee joint of the 18 rats which composed Group I. The second group of 18 rats received additionally doxycycline (doxy) through the gastric tube in doses comparable with those of doxycycline used in humans. The experiment lasted 21 days. The animals were sacrificed after 7, 14 and 21 days in groups of 6 rats each. In sections stained with Safranin 0 semiquantitative histochemical intensity tests were performed on articular cartilage glycosaminoglycans (GAG) using a four-point scale (0–3). In the first group examined destructive lesions in the articular cartilage and weak reactivity on GAG were noted at all stages of the experiment. The intensity of GAG staining was higher in the second group after 14 and especially after 21 days, which may suggest a protective action of doxy on articular cartilage.

9

An evaluation of Ki-67 and PCNA expression in conjunctival and eyelid tumours

76%

Reszec J., Kanczuga-Koda L., Sulkowska M., Koda M., Cylwik J., Barwijuk-Machala M., Sulkowski S.

Folia Morphologica

|

2004

|

tom 63

|

nr 1

The aim of our study was an evaluation of the expression of cell proliferation markers (PCNA and Ki-67) in conjunctival and eyelid papillomas and squamous and basal cell cancers. A series of 9 cases of squamous cell cancer (SCC), 15 cases of basal cell cancer (BCC) and 43 cases of squamous cell papilloma (SCP) were assessed using the immunohistochemical method with monoclonal antibodies. PCNA overexpression was observed in 100% of SCP, in 88.8% of SCC and in 100% of BCC cases. Ki-67 overexpression was seen in 32.5% of cases of SCP, in 22.2% of SCC and in 66.6% of BCC. The results showed that an evaluation of Ki-67 expression is the most valuable cell proliferation marker.

10

Expression of the apoptotic markers in normal breast epithelium, benign mammary dysplasia and in breast cancer

64%

Koda M., Kanczuga-Koda L., Reszec J., Sulkowska M., Famulski W., Baltaziak M., Kisielewski W., Sulkowski S.

Folia Morphologica

|

2004

|

tom 63

|

nr 3

Apoptosis and proliferation are processes associated with the development and progression of breast cancer. The sensitivity of tumour cells to the induction of apoptosis depends on the balance between pro- and anti-apoptotic proteins. The expression of Bak and Bcl-2 was examined using an immunohistochemical method in 71 primary breast cancers. Furthermore, Bcl-2 and Bak were assessed in the normal mammary gland as well as in benign mammary dysplasia adjacent to breast cancer. Positive immunostaining for Bcl-2 was observed in 77.8% of cases of normal breast epithelium (NBE), 93% of benign dysplasia without intraductal proliferation (BBD) as well as in 94% of intraductal proliferative lesions of the breast (BIPL). Expression of Bak was detected in 39% of cases of NBE, 45% of BBD and in 67% of BIPL. In breast cancer Bcl-2 and Bak expression was found in 83% and 70% of the cases studied, respectively. Increased Bcl-2 expression in primary tumours significantly correlated with favourable prognostic factors, namely pT1, G2 and lack of metastases to the regional lymph nodes (p < 0.01, p < 0.03, p < 0.02, respectively). There were no relationships between Bak and the clinicopathological features studied, but our results indicate changes in the expression of Bak during breast cancer development and progression. It would appear to be important to assess and compare pro- and anti-apoptotic proteins between normal mammary gland, benign mammary dysplasia and the primary tumours of breast cancer. This knowledge should be helpful in understanding breast cancer development and progression.

11

Effect of cyclophosphamide-induced generation reactive oxygen forms on ultrastructure of the liver and lung

64%

Sulkowska M., Skrzydlewska E., Sobaniec-Lotowska M., Famulski W., Terlikowski S., Kanczuga-Koda L., Reszec J., Daniszewska I.

Bulletin of the Veterinary Institute in Puławy

|

2002

|

tom 46

|

nr 2

12

Search of reference biomarkers reflecting orbital tissue remodeling in the course of Graves’ orbitopathy

52%

Pawlowski P., Poplawska I., Mysliwiec J., Dik W. A., Eckstein A., Berchner-Pfannschmidt U., Milewski R., Lawicki S., Dzieciol-Anikiej Z., Rejdak R., Reszec J.

Folia Histochemica et Cytobiologica

|

2020

|

tom 58

|

nr 1

13

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

The development of cigarette smoke induced chronic pancreatitis in mice is associated with increased expression of K-Ras and NF-κB

52%

Daniluk J., Daniluk U., Rogalski P., Swidnicka-Siergiejko A., Wasielica-Berger J., Jacek Kucharski J. R., Antonowicz S., Reszec J., Lotowska J. M., Zabielski P., Blachnio-Zabielska A., Dabrowski A.

Annals of Agricultural and Environmental Medicine

|

2022

|

tom 29

|

nr 2

Ograniczanie wyników

HIF-1 expression in retinal ganglion cells and optic nerve axons in glaucoma

Assessment of inflammatory infiltration and angiogenesis in the thrombus and the wall of abdominal aortic aneurysms on the basis of histological parameters and computed tomography angiography study

Wirus brodawczaka ludzkiego a proces apoptozy.

Is littoral cell angioma of the spleen as rare as previously believed in the pediatric population?

AgNOR, Ki-67 and PCNA expression in fibroepithelial tumours of the breast in correlation with morphological features

Mast cells evaluation in meningioma of various grades

The evaluation of human papillomavirus and p53 gene mutation in benign and malignant conjunctiva and eyelid lesions

The influence of doxycycline on articular cartilage in experimental osteoarthrosis induced by iodoacetate

An evaluation of Ki-67 and PCNA expression in conjunctival and eyelid tumours

Expression of the apoptotic markers in normal breast epithelium, benign mammary dysplasia and in breast cancer

Effect of cyclophosphamide-induced generation reactive oxygen forms on ultrastructure of the liver and lung

Search of reference biomarkers reflecting orbital tissue remodeling in the course of Graves’ orbitopathy

The development of cigarette smoke induced chronic pancreatitis in mice is associated with increased expression of K-Ras and NF-κB