PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2000 | 47 | 2 |

Tytuł artykułu

Wystepowanie, biosynteza i wlasciwosci biologiczne flawonoli

Autorzy

Treść / Zawartość

Warianty tytułu

Języki publikacji

PL

Abstrakty

EN
The occurrence, biosynthesis and biological properties of the flavonols as well as their importance for human health were reviewed. Flavonols are the main group of large flavonoids class. In plant tissues widely occur the quercetin and its glycosides in much smaller levels the glycosides of kaempferol, and occasionally- the myricetin. The highest concentration of quercetin glycosides was found, among the food components, in onion and other Allium vegetables. Other important sources of flavonols are the tea infusions and apples, although the bioavailibility rate of the flavonols from onion was much higher than those of tea and apples. It was found that the quercetin and other flavonols reveal the strong antioxidant and antiradical properties. Quercetin shows a protective activity in LDL oxidation and therefore it is important at heart disease prevention. Most likely the flavonols show some anticancer properties, too.

Wydawca

-

Rocznik

Tom

47

Numer

2

Opis fizyczny

s.3-18,rys.,tab.,bibliogr.

Twórcy

autor
  • Instytut Warzywnictwa, ul.Konstytucji 3 Maja 1/3, 96-100 Skierniewice

Bibliografia

  • [1] Bilyk A., Cooper P.L., Sapers G.M. 1984. Varietal differences in distribution of quercetin and kaempferol in onion (Allium cepa L.) tissue. J. Agric. Food Chem. 32: 274-276.
  • [2] Bilyk A., Sapers G.M. 1985. Distribution of quercetin and kaempferol in lettuce, kale, chive, garlic chive, leek, horseradish, red radish, and red cabbage tissues. J. Agric. Food Chem. 33: 226-228.
  • [3] Crozier A., Lean M.E.J., McDonald M.S., Black C. 1997. Quantitative analysis of the flavonoid content of commercial tomatoes, onions, lettuce and celery. J. Agric. Food Chem. 45: 590-595.
  • [4] Das M., Rey P.K. 1988. Lipid antioxidant properties of quercetin in vitro. Biochem. Int. 17: 203-208.
  • [5] de Whalley C. V., Rankin S.M., Hoult J.R.S., Jessup W., Leake D.E. 1990. Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophages. Biochem. Pharmacol. 39: 1743-1750.
  • [6] Formica J.V., Regelson W. 1995. Review of the biology of quercetin and related bioflavonoids. Fd. Chem. Toxic. 33: 1061-1080.
  • [7] Frankel E.N., Kanner J., German J.B., Parks E., Kinsella J.E. 1993. Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine. Lancet 341: 1103-1104.
  • [8] Gazziano J.M., Buring J.E., Breslow J.L., Goldhaber S.Z., Rosner B., van Denburgh M., Willet W., Hennekens C.H. 1993. Moderate alcohol intake increased levels of high-density lipoprotein and its subfractions, and decreased risk of myocardial infection. New England J. Med. 329: 1829-1834.
  • [9] Gryglewski R.J., Korbut R., Robak J., Swies J. 1987. On the mechanism of anti-thrombic action of flavonoids. Biochem. Pharmacol. 36: 317-322.
  • [10] Harborne J.B. 1986. Flavonoids in environment: structure-activity relationships. W: Progress in Clinical and Biological Research. Tom 213. Ed.: V.Cody, E.Middleton jr., and J.B. Harborne. Alan R. Liss New York: 15: 24.
  • [11] Harborne J.B. 1994. The flavonoids. Chapman and Hall London.
  • [12] Havsteen B. 1983. Flavonoids - a class of natural products of high pharmacological potency. Biochem. Pharmacology 32: 1141-1148.
  • [13] Hedin P.A., Wangea S.K. 1986. Roles of flavonoids in plant resistance to insects. W: Progress in Clinical and Biological Research. Tom 213. Ed.: V. Cody, E.Middleton jr., and J.B. Harborne. Alan R. Liss New York: 87-100.
  • [14] Herrmann K. 1988. On the occurrance of flavonoland flavone glycosides in vegetables. Z. Lebensm. Unters. Forsch. 186: 1-5.
  • [15] Hertog M.G.L., Feskens E.J.M., Hollmann P.C.H., Katan M.B., Kromhout D. 1993. Dietary antioxidants flavonoids and risk of coronary heart disease: the Zutphen Elderly Study Lancet 342: 1007-1011.
  • [16] Hertog M.G.L., Hollman P.C.H., Katan M.B. 1992. Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands. J. Agric. Food Chem. 40: 2379-2383.
  • [17] Hertog M.G.L., Hollmann P.C.H., Katan M.B., Kromhout D. 1993. Intake of potentially anticarcinogenic flavonoids and their determinants in adults in the Netherlands. Nutr. Cancer 20: 21-29.
  • [18] Hertog M.G.L., Hollmann P.C.H., van de Putte B. 1993. Content of potentially anticarcinogeruc flavonoids of tea infusions, wines, and fruit juices. J. Agric. Food Chem. 41 : 1242-1246
  • [19] Hertog M.G.L., Kromhout D., Aravansis C., Blacburn H., Buzina R., Fidanza F., Gianpaoli S., Jansen A., Menotti A., Nedeljikovic S., Pekkarinen M., Simic B.S., Toshinue M., Feskens E.J.M., Hollmann P.C.H., Katan M.B. 1995. Flavonoid intake and long term risk of coronary heart disease and cancer in the Seven Country Study. Arch. Inter. Med. 155: 381-386.
  • [20] Hirota S., Shimoda T., Takahama U. 1998. Tissue and spatial distribution of flavonol and peroxidase in onion bulbs and stability of flavonol glucosides during boiling of the scales. J. Agric. Food Chem. 46: 3497-3502.
  • [21] Hollman P.C.H. 1997. Determinants of the absorption of the dietaiy antioxidant flavonoid quercetin in man. Praca doktorska. Landbouwuniversiteit Wageningen: 1-187.
  • [22] Horbowicz M. 1999. Changes of flavonol content during vegetation period and storage of onion. Veget. Crops Res. Bull. 50: 81-91.
  • [23] Horbowicz M., Kotlińska T. 1998. Zróżnicowanie zawartości flawonoli w niektórych uprawnych i dzikich gatunkach z rodzaju Allium. Zesz. Probl. Post. Nauk Roln. 463: 529-537.
  • [24] Kączkowski J. 1993. Biochemia roślin. Tom 2. Metabolizm wtórny. PWN Warszawa: 260-284.
  • [25] Knekt R., Järvinen R., Reunanen A., Maatala J. 1996. Flavonoid intake and coronary mortality in Finland. Brit. Med. J. 312: 478-481.
  • [26] Kühnau J. 1976. The flavonoids: a class of semi-essential food components: their role in human nutrition. World Rev. Nutr. Diet. 24: 117-191.
  • [27] Larson R.A. 1988. The antioxidants of higher plants. Phytochemistry 27: 969-971.
  • [28] Leighton T., Ginther C., Fluss L., Harter W.K., Cansado J., Notario V. 1992. Molecular characterisation of quercetin and quercetin glycosides in Allium vegetables: their effects on malignant cell transformation. W: Phenolic compounds in food and their effects on health. II. Antioxidants and cancer prevention. Ed.: Huang M.T., Ho C.T., Lee C.Y., ACS symposium series no. 507. American Chemical Society Washington DC: 220-238.
  • [29] Middleton E., Kandaswami C. 1994. The impact of plant flavonoids on mammalian biology: implications for immunity, inflamation and cancer. W: The flavonoids: advances in research since 1986. Ed.: Harborne J.B. Chapman and Hall London: 619-652.
  • [30] Moore T.C. 1989. Auxins. W: Biochemistry and physiology of plant hormones. Springer-Verlag New York.
  • [31] National Research Council, 1989. Committee on diet and health. National Academy of Sciences. Diet and Health. National Academy Press Washington.
  • [32] Pamukcu A.M., Yalciner S., Hatcher J.F., Bryan G.T. 1980. Quercetin, a rat intenstinal and bladder carcinogen present in brakem fern (Pteridinum aquilinum). Cancer Res. 40: 3468-3472.
  • [33] Park Y-K., Lee C. Y. 1996. Identification of isorhamnetin 4'-glucoside in onions. J. Agric. Food Chem. 44: 34-36.
  • [34] Patil B.S., Pike L.M. 1995. Distribution of quercetin content in different rings of various coloured onion (Allium cepa L.) cultivars. J. Hort. Sci. 70: 643-650.
  • [35] Patil B.S., Pike L.M., Yoo K.S. 1995. Variation in the quercetin content in different coloured onions (Allium cepa L.). J. Amer. Soc. Hort. Sci. 120: 909-913.
  • [36] Price K.R., Bacon J.R., Rhodes M.J.C. 1997. Effect of storage and domestic processingon the content and composition of flavonoid glucosides in onion (Allium cepa). J. Agric. Food Chem. 45: 938-942.
  • [37] Price K.R., Casuscelli F., Colquhoun I.J., Rhodes M.J.C. 1998. Composition and content of flavonol glycosides in broccoli florets (Brassica oleracea) and their fate during cooking. J. Sci. Food Agric. 77: 468-472.
  • [38] Price S.F., Breen P.J., Schuette M.J., Valladao M., Watson B.T. 1993. Quercetin ingrapes and wine. Am. J. Enol. Viticulture 44: 345.
  • [39] Renaud S., de Lorgeril M. 1992. Wine, alcohol, platelets and the French paradox for coronary heart disease. Lancet 339: 1523-1526.
  • [40] Rice-Evans C.A., Miler N.J. 1996. Antioxidant activities off lavonoids as bioactive components of food. Biochem. Soc. Trans. 24: 790-795.
  • [41] Rimm E.B., Giovanucci E.L., Willet N.C., Colditz G.A., Ascherio A., Rosner B., Stampfer M.J. 1991. Prospective study on alcohol consumption and risk of coronary disease in men. Lancet 338: 464-468.
  • [42] Rimm E.B., Katan M.B., Asherio A., Stampfer M.J., Willet W.C. 1996. Relation between intake of flavonoids and risk of coronary heart disease in male health professionals. Ann. Intern. Med. 125: 384-389.
  • [43] Salunkhe D.K., Bolin H.R., Reddy N.R. 1991. Storage, processing and nutritional quality of fruits and vegetables. 2nd edition. Vol. I. Fresh fruits and vegetables. CRC Press.
  • [44] St. Leger A.S., Cochrane A.L., Moore F. 1979. Factors associated with cardiac mortality in developed countries with particular reference to the consumption of wine. Lancet: 1017-1020.
  • [45] Tomas-Baiberan F.A., Maillard M., Hostellman K. 1988. Antifungal flavonoids from the leaf structures of Helichrysum nitens and from stem bark of Erythrina berteroana. W: Progress in Clinical and Biological Research. Tom 280. Ed.: V. Cody, E. Middleton jr., J.B. Harborne i A. Beretz. Alan R. Liss New York: 61-65.
  • [46] Yoshida M.A., Saska M., Hosakawa N., Marui N., Matsumoto M., Fujioka A.,Nishino H., Aoike A. 1990. The effects of quercetin on cell cycle progression and growth of human cancer cells. FEBS Letters 260: 10-13.
  • [47] Zhu B.T., Ezell E.L., Liehr J.G. 1994. Catechol-O-methyl transferase catalyse rapid O-methylation of mutagenic flavonoids. Metabolic inactivation as a possible reason for their lack of carcinogenicity. J. Biol. Chem. 269: 292-299.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-f0942562-23a2-40eb-9af9-4e99639a96f4
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.