Immunization value of experimental foot-and-mouth disease vaccines prepared from type C virus multiplied in cell cultures

• Autorzy: Wisniewski J. , Baranowski Cz. , Jankowska J. , Kobusiewicz T. , Szkilnik S.
• Języki publikacji: EN

Abstrakty

EN

The growing need for foot-and-mouth disease (FMD) vaccine has caused a number of production laboratories to seek newer, more economical means of virus multiplication, which ensure in vitro cultivation. The oldest of these methods, developed by Frenkel in 1947-1951, is the method of multiplying FMD virus on the epithelium of cattle tongues (8). After improvement this technique was accepted by several institutes for industrial multiplication of FMD virus (15, 9, 23, 22). Multiplication of virus in kidney cell cultures in a monolayer or a culture suspension is a newer method. Kidney cells from calves (11, 12, 13, 18, 23, 24, 4, 1), piglets (21, 14, 12, 20, 17, 13), and cattle fetus kidneys (16) have been found suitable for this purpose. In recent years cultures of cell lines from BHK₂₁ (baby hamster kidneys) have been satisfactory for multiplying FMD virus in monolayers in statically held (bottles or in a rotary apparatus (22, 16, 25, 19), or in special reactors in which cells are multiplied in suspension (10, 3, 22). Many years of work and experiments proceeded the introduction of new methods into production on an industrial scale. The aim of our work was to investigate immunization values of experimental vaccine prepared from type C virus multiplied in cultures of calf kidney cells. Also, we wanted to determine the durability of the immunity on the basis of the level of neutralizing antibodies and experimental infection of immunized cattle.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 1970
• Tom: 14
• Numer: 1-2
• Opis fizyczny: p.24-30,fig.,ref.

Twórcy

autor

Wisniewski J.

• Department of Foot-and-Mouth Disease, Zdunska Wola, The Veterinary Research Institute in Pulawy, Zdunska Wola, Poland

autor

Baranowski Cz.

• Department of Foot-and-Mouth Disease, Zdunska Wola, The Veterinary Research Institute in Pulawy, Zdunska Wola, Poland

autor

Jankowska J.

• Department of Foot-and-Mouth Disease, Zdunska Wola, The Veterinary Research Institute in Pulawy, Zdunska Wola, Poland

autor

Kobusiewicz T.

• Department of Foot-and-Mouth Disease, Zdunska Wola, The Veterinary Research Institute in Pulawy, Zdunska Wola, Poland

autor

Szkilnik S.

• Department of Foot-and-Mouth Disease, Zdunska Wola, The Veterinary Research Institute in Pulawy, Zdunska Wola, Poland

Bibliografia

• 1. Anchew V., Cholakowa R., Boyadjew S.: Veter. Med. Nauki 1, 23, 1965.
• 2. Baranowski Cz.: Diagnostyka typów wirusa pryszczycy stosowana w Zakładzie Pryszczycy I Wet. Instrukcja 1964.
• 3. Behringwerke - Nowe zakłady produkcyjne Behringwerke do hodowli komórkowych. Blauen Hefte 38, 50, 1968.
• 4. Cardassis J., Pappous C., Brovas D., Karavalakis J., Stouraitis P.: Vet. Bull. 37, 6, 2082, 1967.
• 5. Fayet M., Petermann H., Fontaine J., Terre J., Houmiantzeff M.: Ann. Inst. Pasteur 112, 1, 65, 1967.
• 6. Fagg R.: Commission Europeenne de Lutte contre la Fievre Aphteuse. Comite Technique Permanent, Lyon, 28 septembre - 1 octobre 1965.
• 7. Fellowes O.: Ann. New York Academy Science 83, 593, 1960.
• 8. Frenkel S.: Report on the large scale cultivation of foot-and-mouth disease virus and thepreparation and testing of the corresponding vaccines at the Central Veterinary Institute at Amsterdam 1964.
• 9. Girard H., Erol N., Ilerle M.: Bull. Off. Int. Epiz 71, 3-4, 307, 1969.
• 10. Guilloteau B., D’Oultremont Ph., Guerche M., Legrand В., Prunet P.: Bull. Off. Int. Epiz. 71, 1-2, 97, 1969.
• 11. Kobusiewicz T., Wiśniewski J., Szkilnik S., Baranowski Cz., Jankowska J., Łabęcka W.: Medycyna Wet. 24, 6, 339, 1968.
• 12. Krawiec L., Sjusjukin A., Efimow H., Sjergiejew W., Kantow W., Zawjalow N.: Wietierinaria 9, 46, 1967.
• 13. Leunen J., Mammericks M., Strobbe R.: Bull. Off. Int. Epiz. 59, 7-8, 1019, 1963.
• 14. Lichaczew N., Orłow S., Szemanowa C.: Wietierinaria 3, 64, 1963.
• 15. Maćkowiak Cz., Duboulard G., Favre H., Roumiantzeff M., Fontaine J., Terre J., Bornarel P.: Bull. Off. Int. Epiz. 71, 1-2, 3, 1969.
• 16. Mammericks M., Leunen J.: Bull. Off. Int. Epiz. 65, 3-4, 337, 1966.
• 17. Mazzarachio N., Zavagli V., Orfei Z., Amore A., Ravaioli L., Castagnoli B.: Bull. Off. Int. Epiz. 49, 1-2, 91, 1958.
• 18. Mitiew G., Glebinkow Z., Chopow J., Simconow S.: XII-eme Conference de la Commission de la Fievre Aphteuse de l'ОIЕ - Paris, 26-30 novembre 1968.
• 19. Muntiu N., Dohotaru V., Bercan A.: Arohiva Veterinaria 5, 35, 1968.
• 20. Muntiu N., Dohotaru V., Popa M., Bercan A., Sava I.: Lucr. Inst. Cere. Veter. Biopr. Pasteur 2, 1, 1, 1963.
• 21. Muntiu N., Dohotaru V., Daniel R., Bercan A.: Euer .Inst. Cere. Veter. Biopr .Pasteur 4, 3-4, 1, 1965.
• 22. Nardelli L., Orfei Z.: Bull. Off. Int. Epiz. 71, 1-2, 121, 1969.
• 23. Okay G., Sutai M., Bayramoglu O., Oral M., Unluleblebici N., Senturk M., Girard H.: Bull. Off. Int. Epiz. 71, 3-4, 341, 1969.
• 24. Orłow S., Byków J., Ratner L., Moutouzkina Z., Ignatiewa V.: Bull. Off. Int. Epiz. 71, 3-4, 393, 1969.
• 25. Ubertini B., Nardelli L., Dal Prato A., Panina G., Santero G.: Zbl. Veter. Med. 10, 2, 93, 1963.
• 26. Wiśniewski J., Jankowska J., Szkilnik S., Kobusiewicz T.: Medycyna Wet. 25, 3, 152, 1969.