Ograniczanie wyników

Czasopisma help
Autorzy help
Lata help
Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników

Znaleziono wyników: 24

Liczba wyników na stronie
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 2 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych:  toxocariasis
help Sortuj według:

help Ogranicz wyniki do:
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 2 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
Toxocariasis has been highlighted as a potentially important neglected infection of poverty in developed countries that experience substantive health disparities such as the United States. An association between Toxocara infection and lung function, in concert with a relatively high prevalence of infection, may mark an important mechanism by which this infection could contribute significantly to the differential morbidity across different socioeconomic groups and landscapes. To assess the potential relevance of this infection in a dense urban environment, we measured the association between forced expiratory volume in 1 second (FEV1) and serology diagnosed Toxocara infection in a sample of US-born New York City residents. We identified a significant independent association between Toxocara infection and lung function, wherein those with previous Toxocara infection had a 236.9 mL reduced FEV1 compared to those without Toxocara infection even after adjusting for age, sex, ethnicity, level of education, smoking status, body mass index, and pet ownership. These findings from New York City corroborate similar findings in a national sample and, while the cross-sectional data preclude a direct causal relationship, this study identifies a potentially important neglected infection in a dense urban landscape.
Geographic information system (GIS) or Health geography is a geographical identification of the spatial variation of contagion disease and zoonosis risk in certain conditions.
The results of examination of 1264 patients in Poznań area, Poland by an ELISA test with E/S antigen were retrospectively analysed in order to evaluate the place the absorbance values (OD) may have in the clinical interpretation of toxocarosis. Mean OD values in the screened populations (except children living in a heavily contaminated area) were all below 1.500 and in the hospitalised symptomatic patients - all above 1.750. The level of eosinophilia correlated well with OD values. It is postulated that in population screenings the weakly positive OD values (0.600-1.190) are presented separately, as they usually have no clinical implications. The OD values 1.200-1.790 may occur in mild toxocarosis, whereas the values above 1.800 are common in clinically well expressed toxocarosis. Ocular toxocarosis usually have lower OD values. In conclusion OD values are good markers of clinical expression of toxocarosis and have to be considered together with eosinophilia, IgE antibodies response and observed symptoms and signs in a rational clinical evaluation of the Toxocara infection in human patients.
The observation of a group of 168 children treated for toxocariasis shows that the most frequent symptoms at the time of the physical examination were abdominal pains - 41 %; headache was observed in 12% cases. Eosinophilia was found in 9.2% cases. The final diagnosis was based on the results of serological investigation. The level of IgG antibodies was established by the ELISA method using the excretory - secretory antigen of Toxocara canis larvae. A few years of studies lead to the observation that after treatment the return of the level of antibodies to normal is a very slow process - positive results are found in 57% of patients even after 4 to 7 years and the decrease of the mean titre of antibodics does not exceed 45%. The observations show that examination of the level of antibodies in the way hitherto applied does not provide a satisfactory indication of the positive effect of treatment. Therefore, it is necessary to develop a system of additional laboratory tests that will altow a faster evaluation of the effects of treatment of this disease.
Sixty three children, who were living in an area known to be heavily contaminated by dog faeces in the centre of city of Poznań, Poland (Toxocara spp. eggs were found in 53% of 40 g soil samples), were examined for antibodies to Toxocara spp. Five children (7.9%) had high absorbance values in the Toxocara ELISA test. Geophagia and dog’s ownership were the major associated risk factors. Neither present nor past symptoms and signs usually related to toxocarosis were found in any of the seropositive children. The study confirmed that toxocarosis may be clinically inapparent even in an area where exposure to infection is common and serological responses well pronounced.
Sera from 455 patients with diagnosed toxocarosis were examined for the presence of specific IgE by the ε-capture ELISA. Total IgE levels were measured in the sera of 174 patients. Specific IgE was found in 54% of cases, with a high level in 30%. Total IgE level was elevated in 67% of patients. A similar pattern was found in patients with ocular and visceral forms of toxocarosis. There was no statistically significant difference in levels of specific IgE between patients with these forms of the disease. However, we observed significantly higher concentrations of specific IgE among patients who showed high specific IgG activity (titre equal to or higher than 1 : 20,000).
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 2 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.