Due to the current system of integrated cultivation of tomato since 2014, the program was verified to protect tomato against the most dangerous diseases. The aim of the research conducted in the years 2012 and 2013 was to assess the effectiveness of natural products and Bacillus subtilis to protected tomato against late blight and early blight in the prevention system. The reference product was a fungicide containing a mixture of boscalid and pyraclostrobin. Tea tree oil and extract of berries showed good efficacy in the protection of tomato against potato early blight and late blight. A mixture of boscalid and pyraclostrobin showed higher efficacy in reducing the development of these diseases. There were no effects of phytotoxicity. All the tested products increased the yield of tomatoes.