Wyniki wyszukiwania - AGRO

1

Some useful hosting centers and databases for molecular biology on the World Wide Web

100%

Brys M.

Acta Biochimica Polonica

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1996

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tom 43

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nr 4

This article describes the information contained within World Wide Web of potential uses for molecular biologists. The aim is to provide a basic description of the server provided services of bioinformatics, major program coordinator activities, and current contents of genome nucleic acid and protein databases.

2

PDZ domains - common players in the cell signalling

100%

Jelen F., Oleksy A., Smietana K., Otlewski J.

Acta Biochimica Polonica

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2003

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tom 50

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nr 4

PDZ domains are ubiquitous protein interaction modules that play a key role in cellular signaling. Their binding specificity involves recognition of the carboxyl-termi- nus of various proteins, often belonging to receptor and ion channel families. PDZ domains also mediate more complicated molecular networks through PDZ-PDZ interactions, recognition of internal protein sequences or phosphatidylinositol moieties. The domains often form a tandem of multiple copies, but equally often such tandems or single PDZ domain occur in combination with other signaling domains (for example SH3, DH/PH, GUK, LIM, CaMK). Common occurrence of PDZ domains in Metazoans strongly suggests that their evolutionary appearance results from the complication of signaling mechanisms in multicellular organisms. Here, we focus on their structure, specificity and role in signaling pathways.

3

BCL2 and BAX mRNA concentration profile in fibrillary astrocytoma

88%

Mazurek U., Bierzynska-Macyszyn G., Gola J., Orchel J., Slowinski J., Wilczok T.

Folia Histochemica et Cytobiologica. Supplement

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2001

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tom 39

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nr 1

4

p53 and p16 alterations in lung cancer

88%

Niklinski J., Chyczewski L., Niklinska W.

Folia Histochemica et Cytobiologica. Supplement

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2001

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tom 39

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nr 1

5

Introduction to molecular biology of influenza A viruses

75%

Szewczyk B., Bienkowska-Szewczyk K., Krol E.

Acta Biochimica Polonica

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2014

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tom 61

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nr 3

6

Prokaryotic toxin-antitoxin systems - the role in bacterial physiology and application in molecular biology

75%

Bukowski M., Rojowska A., Wladyka B.

Acta Biochimica Polonica

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2011

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tom 58

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nr 1

Bacteria have developed multiple complex mechanisms ensuring an adequate response to environmental changes. In this context, bacterial cell division and growth are subject to strict control to ensure metabolic balance and cell survival. A plethora of studies cast light on toxin-antitoxin (TA) systems as metabolism regulators acting in response to environmental stress conditions. Many of those studies suggest direct relations between the TA systems and the pathogenic potential or antibiotic resistance of relevant bacteria. Other studies point out that TA systems play a significant role in ensuring stability of mobile genetic material. The evolutionary origin and relations between various TA systems are still a subject of a debate. The impact of toxin-antitoxin systems on bacteria physiology prompted their application in molecular biology as tools allowing cloning of some hard-to-maintain genes, plasmid maintenance and production of recombinant proteins.

7

Molecular data on the systematic position of Bactrini (Lepidoptera: Tortricidae)

75%

Razowski J., Tarcz S.

Genus. International Journal of Invertebrate Taxonomy

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2012

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tom 23

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nr 1

8

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Segmented hybridization probes: modulating target affinity and base pairing selectivity

75%

Egetenmeyer S., Geiger E., Richert C.

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

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2012

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tom 93

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nr 3

9

Current and future perspectives in plant embryogenesis

75%

Raghavan V.

Acta Biologica Cracoviensia. Series Botanica. Supplement

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1999

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tom 41

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nr 1

10

Immune phenomena in echinoderms

75%

Glinski Z., Jarosz J.

Archivum Immunologiae et Therapiae Experimentalis

|

2000

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tom 48

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nr 3

11

The minimal genome paradox

75%

Wegrzyn G.

Journal of Applied Genetics

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2001

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tom 42

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nr 3

12

Professor Karol Taylor 1928-1997

75%

Wegrzyn G.

Acta Biochimica Polonica

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1998

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tom 45

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nr 1

13

Professor Karol Taylor

75%

Wegrzyn G.

Acta Microbiologica Polonica

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1997

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tom 46

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nr 4

14

Ribotyping as a molecular biological technique for studying diversity in Shigella isolates - a review

63%

Pal P.

International Letters of Natural Sciences

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2014

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tom 14

Diarrhoea in developing countries is caused by an increasingly long list of bacterial, viral, and parasitic pathogens with rotavirus, Enterotoxigenic Escherichia coli, Campylobacter, Shigella, and Salmonella heading the list. Using methods to detect most of the known enteropathogens, one or more enteropathogen(s) is isolated in two-thirds of diarrhoeal illnesses in the developing world. Deoxyribonucleic acid probes have proved very useful in detecting pathogens such as enterotoxigenic (ETEC), enteroinvasive (EIEC), enteropathogenic E. coli (EPEC), and Shigella but have not yet proved to be particularly rapid or less expensive. Molecular biology has proved useful in epidemiological studies as a means of strain identification and detection of genome diversity. Since the introduction of ribonucleic acid gene restriction patterns as taxonomic tools in 1986, ribotyping has become an established method for systematics, epidemiological, ecological population and genome diversity studies of microorganisms including Shigella. The technological development culminated in the automation of ribotyping which allowed for high-throughput applications. PCR ribotyping has proved being a highly discriminatory, flexible, robust and cost-efficient routine technique which makes inter-laboratory comparison and build of ribotype databases possible, too. The aim of the present review is to determine the present status of ribotyping technique in detecting the diversity in Shigella isolates.

15

Gene expression profile analysis in laryngeal cancer by high-density oligonucleotide microanalysis

63%

Markowski J., Oczko-Wojciechowska M., Gierek T., Jarzab M., Paluch J., Kowalska M., Wygoda Z., Pfeifer A., Tyszkiewicz T., Jarzab B., Niedzielska I., Borgiel-Marek H.

Journal of Physiology and Pharmacology. Supplement

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2009

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tom 60

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nr 1

57-63

The assessment of gene expression profile in laryngeal cancer shall allow to implement molecular biology methods in diagnostics, as well as in prognosis of the course of disease. Thus, it may influence the choice of the most optimal decisions in regards to the method of treatment, extent of surgical procedure, or the necessity of adding post-operative radiotherapy. The aim of the project was to analyse the gene expression profile of laryngeal cancer using oligonucleotide microarrays, aiming to derive novel molecular markers for that carcinoma. The study comprised a group of 14 patients (12 males and 2 females) with squamous cell laryngeal carcinoma, diagnosed and surgically treated between 2005 – 2007 in the ENT Department of the Silesian Medical University in Katowice, Poland. RNA was isolated from frozen tissue fragments. To assess gene expression profile, high density oligonucleotide microarrays (Affymetrix U 133 Plus 2.0) were applied, with over 54 thousand probesets for over 47 thousand transcripts. Four genes, previously not assesed in diagnostic context in laryngeal carcinoma, seemed to be valuable markers of that neoplasm. These are: metalloproteinase ADAM12, cycline-dependent kinase 2 - CDK2, kinesine 14 - KIF14, suppressor 1 of checkpoint - CHES1.

16

Markery molekularne w hodowli rzepaku.

63%

Bartkowiak-Broda I.

Rośliny Oleiste - Oilseed Crops

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1997

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tom 18

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nr 2

581-585

17

Where we are and what we are driving at?

63%

Kacperska A.

Acta Physiologiae Plantarum

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2007

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tom 29

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nr 1 Suppl.

18

Bacterial community DNA extracted from soils polluted with heavy metals

63%

Kozdroj J., van Elsas J. D.

Polish Journal of Environmental Studies

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2000

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tom 09

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nr 5

403-407

This paper describes the application of two direct and one indirect methods for the extraction of microbial community DNA from soils polluted with heavy metals. DNA was extracted directly from soil by a gentle method based on the soil incubation at 37°C with proteinase K and SDS or the method was modified by the addition of bead beating step. The indirect approach was based on the RNA/DNA extraction method. The level of soil contamination did not affect on the yields of DNA extracted and PCR amplification of the target DNA. The results indicated that the DNA obtained by the applied protocols was sufficiently pure for further molecular analyses.

19

Proby charakterystyki systemu CMS polima przy pomocy markerow molekularnych metoda PCR-RAPD.

63%

Matuszczak M., Bartkowiak-Broda I., Gazecka B.

Rośliny Oleiste - Oilseed Crops

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1997

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tom 18

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nr 2

587-595

20

Elastin-like polypeptides-alternative way of recombinant protein purification

63%

Kowalczyk T., Hnatuszko-Konka K., Gerszberg A., Kononowicz A. K.

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

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2013

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tom 94

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nr 3

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