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Content available remote

Microvessel density and CpG island methylation of THBS2 gene in malignant ovarian tumors

100%
Czekierdowski A., Czekierdowska S., Danilos J., Czuba B., Sodowski K., Sodowska H., Szymanski M., Kotarski J.
Journal of Physiology and Pharmacology. Supplement
|
2008
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tom 59
|
nr 4
53-65
2

Evaluation of cardiac muscle microvessel density in children diagnosed with cyanotic heart defects

100%
Jankowska P., Malinska A., Nowicki M., Konwerska A., Wojtalik M., Bobkowski W., Siwinska A.
Folia Histochemica et Cytobiologica
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2013
|
tom 51
|
nr 4
3

Immunohistochemical study on neuropilin 1 (NRP1) immunoexpression in oral squamous cell carcinoma

100%
Stasikowska-Kanicka O., Wagrowska-Danilewicz M., Danilewicz M.
Folia Histochemica et Cytobiologica
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2018
|
tom 56
|
nr 2
4

Angiogenesis in gliomas

100%
Lebelt A., Dzieciol J., Guzinska-Ustymowicz K., Lemancewicz D., Zimnoch L., Czykier E.
Folia Histochemica et Cytobiologica
|
2008
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tom 46
|
nr 1
69-72
5

Characteristics of dental pulp in human upper first premolar teeth based on immunohistochemical and morphometric examinations

100%
Tomaszewska J. M., Miskowiak B., Matthews-Brzozowska T., Wierzbicki P.
Folia Histochemica et Cytobiologica
|
2013
|
tom 51
|
nr 2
6
Content available remote

Microvessel density assessment in benign and malignant endometrial changes

100%
Czekierdowski A., Czekierdowska S., Czuba B., Cnota W., Sodowski K., Kotarski J., Zwirska-Korczala K.
Journal of Physiology and Pharmacology. Supplement
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2008
|
tom 59
|
nr 4
45-51
7

Pericytes and microvessel density assessment in women with ovarian malignant tumors

100%
Czekierdowska S., Rolinski J., Czekierdowski A., Bednarek W., Kotarski J.
Polish Journal of Environmental Studies
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2004
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tom 13
|
nr Suppl.2, Part 1
Objective: The aim of this study was to assess ovarian cancer angiogenesis by comparing intratumoral microvessel density (MVD) with pericytes expression. Methods: Tumor specimens from 34 women operated because of malignant adnexal tumors were evaluated. Pericytes were assessed with anti-desmin antibody and microvessels were counted following CD-34 antigen detection. Histological type, grading, FIGO stage and menopausal status were compared with MVD and pericytes expression. Results: The means of MVD in serous and mucinous tumors were 25 (range: 8-83) and 22 (range: 8-50), respectively. The difference between medians of MVD and mean number of pericytes per high power field were not statistically significant. Also, there was no correlation between assessed markers and differentiation grade and FIGO stage and tumor type. Conclusion: MVD counting with CD-34 antigen, but not desmin expression for pericytes detection seems to be a useful parameter for neoangiogenesis assessment in ovarian cancers.
8

The morphological analysis of vasculature in thyroid tumours: immunoexpression of CD34 antigen

100%
Rzeszutko M., Rzeszutko W., Dziegiel P.
Folia Histochemica et Cytobiologica
|
2004
|
tom 42
|
nr 4
9

Maspin and c-erbB-2 expression in correlation with microvessel density in invasive ductal breast cancer

100%
Sopel M., Kasprzyk I., Berdowska I.
Folia Histochemica et Cytobiologica
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2005
|
tom 43
|
nr 2
10

Prognostic significance of CD34 expression in early cervical squamous cell carcinoma

100%
Lenczewski A., Terlikowski S. J., Sulkowska M., Famulski W., Sulkowski S., Kulikowski M.
Folia Histochemica et Cytobiologica
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2002
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tom 40
|
nr 2
11

A comparison of Bcl-2 expression, microvessel density and color Doppler sonography in the benign and malignant ovarian tumors

80%
Czekierdowska S., Rolinski J., Czekierdowski A., Bednarek W., Szumilo J., Kotarski J.
Polish Journal of Environmental Studies
|
2004
|
tom 13
|
nr Suppl.2, Part 1
To compare Color Doppler sonography with immunohistochemical microvessel density and Bcl-2 assessement in women with benign and malignant adnexal tumors we examined 112 women with adnexal tumors with the use color Doppler sonography (B&K 2002 ADI and GE Voluson 730 scanners) performed before the surgical procedure. Histological type, grading, FIGO stage and menopausal status were compared with MVD and Bcl-2 expression assessed with immunohistochemistry on parafín embedded tumor specimens. Results: Sixty-seven tumors were benign and 45 tumors were malignant. The mean age of the studied women was 40,4 years; ±SD, 11,5 years. Color Doppler sonography revealed that in most malignant tumors there was a low resistance to flow (mean PI= 0,56, SD=0,36). Benign tumors also had higher pulsatility indices than malignant tumors (PI=1,21 and SD=0,48; p=0,02, Mann-Whitney U-test). Also, there was a statistically significant difference between MVD in benign and malignant tumors (Mann-Whitney U test, PO.OO 1). No significant difference in the percentage of Bcl-2 stained cells in both malignant and benign tumor samples was found. Conclusion: Microvessel density assessed with CD-34 and color Doppler blood flow assessement are useful in ovarian tumors vascularity studies. Bcl-2 expression is probably not a useful marker of angiogenic tumor character.
12

Antigen levels of urokinase-type plasminogen activator receptor and its gene polymorphism related to microvessel density in colorectal cancer

80%
Przybylowska K., Szemraj J., Kulig A., Dziki A., Ulanska J., Blasiak J.
Acta Biochimica Polonica
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2008
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tom 55
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nr 2
357-363
We determined the distribution of genotypes and frequencies of alleles of the (CA)n repeat polymorphism in intron 3 of the urokinase plasminogen activator receptor (uPAR)gene, uPAR antigen levels and microvessel density (MVD) in tumour and distant mucosa samples from 52 patients with colorectal cancer. The uPAR level was higher for patients with high MVD comparing to patients with lower MVD which may suggest that uPAR can be correlated with progression of colorectal cancer. The significant relationship between the high MVD and uPAR antigen level appeared to be independent of the (CA)n repeat polymorphism because no differences in the level of uPAR antigen between carriers of alleles were found. The received results, indicate that uPAR might be considered as a target in colorectal cancer patients’ therapy
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