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1

Iron metabolism and hepcidin concentration in teenagers before and after exercise in relation to the HFE gene status

100%
Kaczorowska-Hac B., Luszczyk M., Antosiewicz J., Kaczor J. J.
Baltic Journal of Health and Physical Activity. The Journal of Gdansk University of Physical Education and Sport
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2019
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tom 11
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nr 2
2
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
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Role of Sinorhizobium meliloti glutaredoxins in nitrogen-fixing symbiosis

100%
Benyamina S., Alloing G., Rouhier N., Jacquot J., Puppo A., Frendo P.
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
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2013
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tom 94
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nr 2
3
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
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Parameters of protein and iron metabolism in dairy cows during periparturient period

84%
Kurpinska A., Jarosz A., Skrzypczak W.
Acta Scientiarum Polonorum. Zootechnica
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2019
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tom 18
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nr 3
4

Effect of diet composition and mixture of selected food additives on the erythrocytic system and iron metabolism in peripheral blood of male rats

84%
Sadowska J., Kuchlewska M.
Acta Scientiarum Polonorum. Technologia Alimentaria
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2011
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tom 10
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nr 4
Background. Metabolic processes of food additives which are “exogenous xenobiotics” are catalysed, primarily, by enzymes located in microsomes of hepatocytes affiliated to P-450 cytochrome superfamily, containing iron. The aim of the study was to investigate the effect of diet composition and selected food additives on the erythrocyte system and iron metabolism in peripheral blood of male rats. Material and methods. The experiment was carried out on 30 male rats sorted into three equinumerous groups. For drinking animals received pure, settled tap water, animals from group III were receiving additionally an aqueous solution of sodium (nitrate), potassium nitrite, benzoic acid, sorbic acid and monosodium glutamate. Results. Ascertained a significant effect of changes in diet composition on the increase in hematocrit marker value and the count of red blood cells in blood of animals examined. Used food additives diminished hemoglobin concentration, hematocrit value and red blood cell count, diminishing also iron concentration in serum, the total iron binding capacity and transferrin saturation with iron. Conclusions. Analysis of the results allowed ascertain adverse changes in values of the erythrocytic system markers, occurring under the influence of the applied mixture of food additives. Used food additives change the iron metabolism, most likely from the necessity of applied xenobiotics biotransformation by heme-containing monoxygenases of P-450 cytochrome.
5

Influence of hepcidin on iron metabolism

84%
Kosla T., Skibniewska E. M.
Medycyna Weterynaryjna
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2010
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tom 66
|
nr 05
291-293
The main role of iron is being part of haemoglobin, whose level it stabilizes; however, iron also plays a very important role in immunological processes and the metabolism of the organism. Hepcidin is a peptide hormone. It was first isolated from human blood and urine, and its release was attributed to the liver. A failure to produce hepcidin is related to iron overload, while its excessive production to anaemia caused by iron deficit. The releasing of hepcidin also affects hypoxia and inflammation through inhibiting these processes in patients with haemochromatosis. There are three forms of the regulation of the iron level: the first is a regulation in cellular storages, the second is erythropoiesis and the third is a dietary regulator. Hepcidin was identified as a regulator which communicates the level of iron reserves in the organism to intestine cells responsible for the absorption of iron. In inflammatory conditions, when the organism wishes to cause alimentary iron deficit, hepcidin production increases even a hundred fold, thus leading to anaemia. Hepcidin is also a stimulator of inflammation as an antibacterial factor produced in the liver parenchyma. It decreases the absorption of iron in the intestines and increases the secretion of iron to the reticuloendothelial system. Experiments on animals deprived of hepcidin and animals with its excess make it possible to understand iron homeostasis and confirm the role of hepcidin as a hormone regulating iron metabolism.
6
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Role of hepcidin in physiology and pathophysiology. Emerging experimental and clinical evidence

84%
Wojciechowska M., Wisniewski O. W., Kolodziejski P., Krauss H.
Journal of Physiology and Pharmacology
|
2021
|
tom 72
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nr 1
7

Lymphocyte labile iron pool, plasma iron, transferrin saturation and ferritin levels in colon cancer patients

84%
Gackowski D., Kruszewski M., Banaszkiewicz Z., Jawien A., Olinski R.
Acta Biochimica Polonica
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2002
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tom 49
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nr 1
Patients with colorectal carcinoma showed statistically significant lower values of transferrin saturation, total iron binding capacity and serum iron level as compared with control group, while the level of ferritin and the size of labile iron pool in carci­noma patients were higher, although this difference was not statistically significant. Our observations are in favour of the hypothesis which suggests that changes in iron metabolism restrict iron availability for tumour cells and as consequence, slow their growth.
8
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An overall view of the process of the regulation of human iron metabolism

67%
Formanowicz D., Formanowicz P.
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
|
2011
|
tom 92
|
nr 2
9
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Do changes in iron metabolism contribute to the acceleration of the atherosclerosis process?

67%
Formanowicz D.
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
|
2011
|
tom 92
|
nr 2
10
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The role of iron regulatory proteins in the control of iron metabolism in mammals

67%
Stys A., Starzynski R. R., Lipinski P.
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
|
2011
|
tom 92
|
nr 1
11
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
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Pathogenesis and clinical consequences of iron overload in chronic hepatitis C - impact of host and viral factors related to iron metabolism

67%
Sikorska K., Romanowski T., Bielawski K. P.
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
|
2011
|
tom 92
|
nr 1
12

Lactoferrin restoration of lymphocyte and macrophage content in cyclophosphamide-treated mice

67%
Artym J., Zimecki M.
Cellular and Molecular Biology Letters
|
2002
|
tom 07
|
nr Suppl.
13
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
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Obesity and iron metabolism

59%
Zekanowska E., Boinska J., Giemza-Kucharska P., Kwapisz J.
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
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2011
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tom 92
|
nr 2
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