Wyniki wyszukiwania

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Galectin-1 expression in innervated and denervated skeletal muscle

100%

Svensson A., Tagerud S.

Cellular and Molecular Biology Letters

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2009

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tom 14

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nr 1

128-138

Galectin-1 is a soluble carbohydrate-binding protein with a particularly high expression in skeletal muscle. Galectin-1 has been implicated in skeletal muscle development and in adult muscle regeneration, but also in the degeneration of neuronal processes and/or in peripheral nerve regeneration. Exogenously supplied oxidized galectin-1, which lacks carbohydrate-binding properties, has been shown to promote neurite outgrowth after sciatic nerve sectioning. In this study, we compared the expression of galectin-1 mRNA and immunoreactivity in innervated and denervated mouse and rat hind-limb and hemidiaphragm muscles. The results show that galectin-1 mRNA expression and immunoreactivity are up-regulated following denervation. The galectin-1 mRNA is expressed in the extrasynaptic and perisynaptic regions of the muscle, and its immunoreactivity can be detected in both regions by Western blot analysis. The results are compatible with a role for galectin-1 in facilitating reinnervation of denervated skeletal muscle.

2

Neural impacts on the regeneration of skeletal muscles

100%

Pinter S., Mendler L., Dux L.

Acta Biochimica Polonica

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2003

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tom 50

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nr 4

The regeneration of skeletal muscles is a suitable model to study the development and differentiation of contractile tissues. Neural effects are one of the key factors in the regulation of this process. In the present work, effects of different reinnervation protocols (suture or grafting) were studied upon the regenerative capacity of rat soleus muscles treated with the venom of the Australian tiger snake, notexin, which is known to induce complete necrosis and subsequent regeneration of muscles. Morphological and motor endplate analysis indicated that the regenerative capacity of denervated, and thereafter surgically reinnervated muscles remains impaired compared to that of normally innervated muscles, showing differences in the muscle size, fiber type pattern and motor endplate structure, even 35 days after the notexin injection. A lack or deficiency of secreted neural factors, deterioration of satellite cells and/or incomplete recovery of the sutured or grafted nerves may be the cause of these discrepancies in the regeneration process.

3

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Effect of denervation and tenotomy on nucleotidase activity in rat skeletal muscles

100%

Rutkiewicz J., Czarnowski D., Gorski J.

Journal of Physiology and Pharmacology

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1993

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tom 44

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nr 4

4

Denervation of arterial muscle rings in the limbs of the experimental animals

86%

Wegrzyn M., Tokarska E., Huk-Wieliczuk E.

Bulletin of the Polish Academy of Sciences. Biological Sciences

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1999

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tom 47

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nr 1

5

Influence of alpha-ketoglutarate on cortical bone atrophy after denervation of the humerus in turkey

86%

Tatara M. R., Silmanowicz P., Majcher P., Krupski W., Studzinski T.

Bulletin of the Veterinary Institute in Puławy

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2005

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tom 49

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nr 1

6

Denervation of the porcine ovaries performed during the early luteal phase influenced morphology and function of the gonad

58%

Jana B., Dzienis A., Panczyszyn J., Rogozinska A., Wojtkiewicz J., Skobowiat C., Majewski M.

Reproductive Biology

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2005

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tom 05

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nr 1

Ograniczanie wyników

Galectin-1 expression in innervated and denervated skeletal muscle

Neural impacts on the regeneration of skeletal muscles

Effect of denervation and tenotomy on nucleotidase activity in rat skeletal muscles

Denervation of arterial muscle rings in the limbs of the experimental animals

Influence of alpha-ketoglutarate on cortical bone atrophy after denervation of the humerus in turkey

Denervation of the porcine ovaries performed during the early luteal phase influenced morphology and function of the gonad