Wyniki wyszukiwania

1

Effect of diazepam on adrenal cortex stress reaction

100%

Beszczynska B., Siejka A.

Acta Biologica Cracoviensia. Series Zoologia

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2003

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tom 45

2

The preventive role of Spirulina platensis (Arthrospira platensis) in immune and oxidative insults in a stress-induced rat model

86%

Seyidoglu N., Koseli E., Gurbanli R., Aydin C.

Journal of Veterinary Research

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2021

|

tom 65

|

nr 2

3

Increased gene expression of selected vesicular and glial glutamate transporters in the frontal cortex in rats exposed to voluntary wheel running

86%

Graban J., Hlavacova N., Jezova D.

Journal of Physiology and Pharmacology

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2017

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tom 68

|

nr 5

4

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Effect of short-term fasting on the expression of ACTH (cMC2) receptor in the adrenal glands of chickens (Gallus gallus domesticus)

86%

Szpregiel I., Wronska D.

Roczniki Naukowe Polskiego Towarzystwa Zootechnicznego

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2021

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tom 17

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nr 3

5

Effect of constitutive- and inducible-cyclooxygenase in the carbachol-induced pituitary-adrenocortical response during social stress

86%

Bugajski J., Gadek-Michalska A., Bugajski A. J.

Journal of Physiology and Pharmacology

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2002

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tom 53

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nr 3

Acetylcholine potently stimulates the hypothalamic-pituitary-adrenal (HPA) axis. Cholinergic receptor agonist carbachol, given intraperitoneally (i.p.) or into the lateral cerebral ventricle (i.c.v.) to non-anesthetized rats acts via multiple pathways to stimulate the HPA axis. The present study sought to determine 1) the functional selectivity of carbachol for cholinergic muscarinic and/or nicotinic receptors involved in the stimulation of HPA axis; 2) the involvement of prostaglandins (PGs) generated by constitutive and inducible cyclooxygenase (COX-1 and COX-2) in the carbachol-induced ACTH and corticosterone secretion in non-stressed rats and animals exposed to social crowding stress for 7 days (24 per a cage for 6). Carbachol was given i.c.v. or i.p. and cholinergic receptor antagonists or cyclooxygenase isoenzyme antagonists were given by the same routes 15 min earlier. One hour after the last injection trunk blood was taken for ACTH and corticosterone determinations. Atropine (0.1 µg i.c.v.), a cholinergic receptor antagonist, totally abolished the carbachol (2 µg i.c.v.)-induced ACTH and corticosterone secretion and mecamylamine (20 µg i.c.v.), a selective nicotinic receptor antagonist, did not affect this secretion. This finding indicates that carbachol functions as a selective central cholinergic muscarinic receptor agonist for the HPA axis stimulation. Crowding stress significantly diminished the carbachol (0.2 mg/kg i.p.)-induced plasma ACTH and corticosterone levels measured 1 hr after administration. Pretreatment with indomethacin (2 mg/kg i.p.), a non-selective cyclooxygenase inhibitor, significantly diminished the ACTH and corticosterone responses to carbachol (0.2 mg/kg i.p.) in control rats and moderately decreased these responses in stressed rats. Piroxicam (0.2 and 2.0 mg/kg i.p.), a COX-1 inhibitor, considerably impaired the carbachol-induced ACTH and corticosterone responses in control rats and markedly diminished these responses in stressed rats. A selective COX-2 blocker, compound NS-398 (0.2 and 2.0 mg/kg i.p.), substantially decreased the carbachol-induced hormones secretion in control rats but did not markedly alter this secretion in stressed rats. These results indicate that in the carbachol-induced HPA axis activation PGs generated by COX-1 are considerably and to a much greater extent involved than PGs generated by COX-2. Social stress markedly diminishes the mediation of PGs generated by COX-1 but PGs synthesized by COX-2 do not substantially participate in the carbachol-induced HPA response.

6

Adrenocortical variability in the life history of bank voles

86%

Bujalska G., Evsikov V., Gerlinskaya L., Grika L., Grum L., Moshkin M.

Polish Ecological Studies

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1994

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tom 20

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nr 3-4

7

Changes in the activity of selected adaptive enzymes in chicken liver after single gamma irradiation

86%

Falis M., Benova K., Toropila M., Sesztakova E., Legath J.

Bulletin of the Veterinary Institute in Puławy

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2004

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tom 48

|

nr 4

8

Psychosocial stress affects the involvement of prostaglandins and nitric oxide in the lipopolysaccharide-induced hypothalamic-pituitary-adrenal response

86%

Gadek-Michalska A., Spyrka J., Bugajski J.

Journal of Physiology and Pharmacology

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2005

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tom 56

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nr 2

The role of prostaglandins and nitric oxide (NO), generated after peripheral lipopolysaccharide (LPS) administration, in the adaptation of hypothalamic-pituitary-adrenal (HPA) axis under stressful circumstances remains to be elucidated. The aim of the present study was to assess the effect of chronic repetitive restraint or social crowding stress on the involvememt of nitric oxide and prostaglandins in the LPS-induced pituitary-adrenocortical response. Male Wistar rats were restrained in metal tubes 2x10 min/day or crowded in cages for 7 days prior to treatment. All compounds were injected i.p., cyclooxygenase (COX) and nitric oxide synthase (NOS) inhibitors 15 min before LPS. Two hrs after injection LPS induced a significant increase in ACTH and corticosterone secretion. Repeated restraint impaired more potently than crowding stress the LPS-induced HPA-response. Indomethacin, a non-selective COX inhibitor, considerably reduced the LPS-induced HPA response in non-stressed rats and to a lesser extent diminished this response in repeatedly restrained or crowded rats. Neuronal NOS inhibitor, Nw-nitro-L-arginine decreased the LPS-induced HPA response, more potently in control than crowded rats. Aminoguanidine, an iNOS inhibitor, diminished the LPS-elicited ACTH response in crowded rats. These results indicate that prostaglandins and NO generated by neuronal and inducible NOS are involved in the LPS-induced HPA axis response under basal conditions and during its adaptation to chronic social stress circumstances.

9

Central histaminergic mechanism in the corticosterone response to clonidine

86%

Bugajski J., Gadek-Michalska A., Borycz J., Bugajski A. J.

Journal of Physiology and Pharmacology

|

1993

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tom 44

|

nr 3

10

Social crowding stress diminishes the pituitary-adrenocortical and hypothalamic histamine response to adrenergic stimulation

86%

Bugajski J., Gadek-Michalska A., Borycz J.

Journal of Physiology and Pharmacology

|

1993

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tom 44

|

nr 4

11

Effect of adrenalectomy and corticosterone on cocaine-induced sensitization in rats

86%

Przegalinski E., Filip M., Siwanowicz J., Nowak E.

Journal of Physiology and Pharmacology

|

2000

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tom 51

|

nr 2

12

Effect of some antidepressants on the low corticosterone concentration-induced gene transcription in LMCAT fibroblast cells

86%

Otczyk M., Mulik K., Budziszewska B., Jaworska-Feil L., Basta-Kaim A., Kubera M., Jagla G., Nowak W., Lason W.

Journal of Physiology and Pharmacology

|

2008

|

tom 59

|

nr 1

The aim of the present study was to investigate effects of some classical and new antidepressants on functional activity of the glucocorticoid receceptor (GR) induced by low corticosterone concentration in mouse fibroblast cells stably transfected with mouse mammary tumor virus-chloramphenicol acetyltransferase plasmid (LMCAT cells). We found that the transcriptional activity of GR stimulated by 50 nM corticosterone was strongly attenuated by imipramine, desipramine, fluoxetine and tianeptine in a concentration-dependent way, whereas reboxetine had only a weak effect and venlafaxine was inactive. Further study revealed that the inhibitor of c-Jun N-terminal kinase - mitogen-activated protein kinase (JNK-MAPK), SP600125 (0.1 µM), reversed the imipramine-induced suppression of GR function, whereas the inhibitor of extracellular signal-regulated kinase (ERK)-MAPK, PD 98059 (15µM), potentiated the antidepressant action. No effect of selective inhibitors of p38-MAPK, phosphatidylinositol 3-kinase (PI3-K)/Akt, and glycogen synthase kinase (GSK-3) on the imipramine-induced inhibition of GR function was detected. These data indicate that the functional activity of GR evoked by low corticosterone concentration in LMCAT cells is efficiently inhibited by tricyclic antidepressants. Moreover, it was found that JNK- and ERK-MAPK were oppositely involved in the regulation of the imipramine-induced inhibition of the GR functional activity. Thus, the present study supports the notion that the interaction of antidepressants with GR may play a role in attenuating pathological hyperactivity of HPA axis in depression.

13

Effect of corticotropin releasing hormone on the pituitary-adrenocortical activity under basal and social stress conditions

86%

Bugajski J., Gadek-Michalska A., Olowska A., Borycz J., Bugajski A. J.

Journal of Physiology and Pharmacology

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1994

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tom 45

|

nr 4

14

Calcium channel blockers impair the pituitary-adrenocortical responses to central adrenergic receptors stimulation

86%

Borycz J., Bugajski A. J., Gadek-Michalska A., Bugajski J.

Journal of Physiology and Pharmacology

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1993

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tom 44

|

nr 2

15

Effect of social stress on COX-1 and COX-2-induced alterations in the adrenergic agonists-evoked hypothalamic-pituitary-adrenal responses

86%

Bugajski J., Gadek-Michalska A., Glod R., Bugajski A. J.

Journal of Physiology and Pharmacology

|

2001

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tom 52

|

nr 4,2

The purpose of the present study was to investigate the contribution of prostaglandins (PGs) synthesized by constitutive (COX-1) and inducible (COX-2) cyclooxygenase to stimulation of the hypothalamic-pituitary-adrenal (HPA) axis by adrenergic receptor agonists in rats under social crowing stress 3 days, (21 per a cage for 6) animals. The effects of phenylephrine, clonidine and isoprenaline, an alpha1-, alpha2- and ß-adrenergic agonist, respectively, in the presence and absence of COX-1 inhibitor, piroxicam, and COX-2 inhibitor, compound NS-398, on ACTH and corticosterone secretion in stressed rats were compared with these effects in non-stressed animals. All drugs were given intracerebroventricularly (i.c.v.), COX inhibitors 15 min before adrenergic agonists. Piroxicam (0.02 µg) and NS-398 (0.1 µg) significantly reduced the phenylephrine (30 µg) -induced ACTH and corticosterone secretion in both stressed and non-stressed rats. Piroxicam (0.02 µg) and NS-398 (0.01 µg) moderately decreased the clonidine (10 µg) -evoked hormone responses in control rats but did not alter these responses in stressed rats. Piroxicam (0.2 µg) and NS-398 (0.1µg) moderately diminished the isoprenaline (20 µg)-evoked ACTH and corticosterone response in control rats, while in stressed rats these inhibitors did not significantly alter the isoprenaline-induced rise in ACTH and corticosterone secretion. These results indicate that in hypothalamic structures involved in the regulation of adrenergic agonists-induced HPA stimulation COX-2 is expressed under physiological synaptic activity. Social crowding stress does not alter the significant involvement of prostaglandins in the HPA response induced by stimulation of central alpha1-adrenergic receptors. Prostaglandins are of lesser importance in activation of the HPA axis by alpha2-and ß-adrenergic receptors under basal and social stress conditions.

16

Ethanol-induced modifications in immune and endocrine parameters of rats exhibiting different ethanol preferences

72%

Baranska A., Oczkowski M., Dyr W., Kostowski W., Skwarlo-Sonta K., Gromadzka-Ostrowska J.

Acta Biologica Cracoviensia. Series Zoologia

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2007

|

tom 49

13-18

17

The effect of oxytocin on cortisol and corticosterone secretion in cyclic gilts - in vivo and in vitro studies

72%

Kotwica G., Kaminska B., Franczak A., Kurowicka B., Staszkiewicz J., Skowronski M. T., Krazinski B., Okrasa S.

Reproductive Biology

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2004

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tom 04

|

nr 1

18

Effect of predator-induced maternal stress during gestation on growth in root voles Microtus oeconomus

72%

Bian J., Wu Y., Liu J.

Acta Theriologica

|

2005

|

tom 50

|

nr 4

473-482

We studied the effect of maternal stress evoked by a severe stressor from the cues of predation risk during gestation on the growth of offspring in root volesMicrotus oeconomus Pallas, 1776. Body mass of both male and female offspring was significantly reduced in the period from birth to weaning. Females showed compensatory growth after weaning, whereas males maintained low body mass at weaning into adulthood. Maternal stress led to an elevated plasma corticosterone level in male offspring, but did not affect that of female offspring. Corticosterone levels remained elevated in males from stressed dams into adulthood. Increased levels of plasma corticosterone may have led to the inhibition of pituitary growth hormone and a chronically abnormal energy mobilization, considering the greater energy and metabolic requirements of male offspring, this may account for the sex-specific differences in compensatory growth. We suggest that in the high stress situation, endocrine-based sex-biased effects of maternal stress as a primary factor can lead to long-term physical and ecological consequences for male offspring.

19

Effect of thermal stress on physiological parameters of broiler chickens after injection of linseed oil into the yolk sac

72%

Sosnowka-Czajka E., Skomorucha I., Herbut E.

Annals of Animal Science

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2007

|

tom 07

|

nr 1

20

Response of broiler chickens from three genetic groups to different stocking densities

72%

Skomorucha I., Muchacka R., Sosnowka-Czajka E., Herbut E.

Annals of Animal Science

|

2009

|

tom 09

|

nr 2

175-184

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