Preferencje help
Polish version English version Język
Widoczny [Schowaj] Abstrakt
Liczba wyników

Znaleziono wyników: 14

Liczba wyników na stronie
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych:  antitumour effect
help Sortuj według:

help Ogranicz wyniki do:
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
1

Increase of the antitumor effect of liposomal octadecyl-piperidinoyl-phosphate: influence of composition on the final effect

100%
Zeisig R.
Cellular and Molecular Biology Letters
|
1999
|
tom 04
|
nr 2
2

Antitumor effect of murine dendritic and tumor cells transduced with IL-2 gene

84%
Wojas-Turek J., Pajtasz-Piasecka E., Rossowska J., Piasecki E., Dus D.
Folia Histochemica et Cytobiologica
|
2012
|
tom 50
|
nr 3
3

The influence of heterocyclic compound - PAMAM dendrimer complexes on evoked electrical responses in slices of hypoxic brain tissue

84%
Potkin V. I., Shcharbin D., Denisov A. A., Paschkevich S. G., Bryszewska M., Petkevich S. K., Kletskov A. V., Lapotko D. O., Kazbanov V. V., Gurinovich T. A., Kulchitsky V. A.
Cellular and Molecular Biology Letters
|
2014
|
tom 19
|
nr 2
We used complexes between a fourth generation polyamidoamine (PAMAM) dendrimer and one of two heterocyclic compounds — 1-(6-hydroxyhexyl)-3-(5-phenyl-isoxazole-3-yl)-urea or 5-phenyl-isoxazole-3-carboxylic acid — to reduce oxygen consumption in transverse slices of the hippocampus taken from 4-week old male rats. In vitro electrophysiological experiments revealed that the inhibitory effect of the hypoxic state on the evoked responses was enhanced in the presence of the complexes. The data were analyzed in terms of the potential antitumor effects of these complexes.
4

Astragaloside IV exerts anti-tumor effect on murine colorectal cancer by re-educating tumor-associated macrophage

84%
Liu F., Ran F., He H., Chen L.
Archivum Immunologiae et Therapiae Experimentalis
|
2020
|
tom 68
|
nr 6
5

Mouse multivalent IgG [2a,b] antibody - ricin A-chain immunotoxins combined with homologous or heterologous interleukin 2 in the treatment of a murine malignant lymphoproliferation [EL4]

84%
Mota G., Marches R., Cialacu V., Roman V., Kozma E., Margineanu M., Dima S., Moraru I. I.
Archivum Immunologiae et Therapiae Experimentalis
|
1996
|
tom 44
|
nr 2-3
6
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Ultrastructural changes of Ehrlich ascites tumor cells after intraperitoneal recombinant human tumor necrosis factor-alpha administration

84%
Terlikowski S. J., Sulkowski S. T.
Bulletin of the Veterinary Institute in Puławy
|
2001
|
tom 45
|
nr 2
Swiss albino male mice were inoculated intraperitoneally (i.p.) with Ehrlich ascites tumor (EAT) and treated i.p. with recombinant human tumor necrosis factor-α (rhTNF-) three time a week in doses of 5, 7.5 and 10μg for 2 weeks, respectively. The effect of the cytokine on EAT was evaluated by the rate of tumor growth inhibition and ultrastructural changes in EAT cell. After the applied doses of rhTNF-α, inhibition of tumor growth was found. The number of EAT cells decreased after 7.5 and 10μg of rhTNF-α (P<0.001). Ultrastructural study demonstrated a cytotoxic effect of the cytokine on EAT cells.
7

The diverse effect of topoisomerase I specific inhibitor [ camptothecin ] on normal and BCR-ABL - dependent hematopoietic cells proliferation: therapeutic implications

84%
Fertala J., Nieborowska-Skorska M., Calabretta B., Skorski T.
Folia Histochemica et Cytobiologica
|
1995
|
tom 33
|
nr 3
8

Differential antitumor effect of essential oils and their major components of Thymus broussonettii: relationship to cell cycle and apoptosis induction

67%
Jaafari A., Ait Mouse H., Ait M'Bark L., Tilaoui M., Elhansali M., Lepoivre M., Aboufatima R., Melhaoui A., Chait A., Zyad A.
Herba Polonica
|
2009
|
tom 55
|
nr 2
36-50
Thymus broussonettii, a Moroccan endemic plant, exists in two chemotypes. The aim of our study is to compare the cytotoxic activity of their essential oils and major products as well as their effect on cell cycle and apoptosis induction. The chemical composition analysis of essential oils by GC-SM revealed that the lasts are rich and diverse and the major products of the chemotypes TbA and TbE are carvacrol and thymol, respectively. The in vitro cytotoxic effect study against five tumor cell lines shows that TbA essential oil, rich in carvacrol, has an important cytotoxic effect, higher than that of TbE, rich in thymol. This result is confirmed by comparing cytotoxic effect of carvacrol and thymol. Furthermore, TbA EO /carvacrol and TbE EO /thymol induce cell cycle arrest at S and G0/G1 phases, respectively. On the other hand, carvacrol, most cytotoxic in vitro, was studied for its effect on solid tumor in vivo and apoptosis-induction. Our results show that carvacrol, administred by gavage, has an important effect on solid tumor and induce apoptosis in P815 tumor cell line.
9

In vitro and in vivo analyses of the biological activity of RGD peptides towards Ab Bomirski melanoma

67%
Okroj M., Dobrzanska-Paprocka Z., Rolka K., Bigda J.
Cellular and Molecular Biology Letters
|
2003
|
tom 08
|
nr 4
The RGD sequence is present in many extracellular matrix proteins and intracellular proteins, including caspases. Synthetic RGD peptides may affect adhesion, migration and tumour metastasis, or directly induce apoptosis. Several RGD peptides were synthesised, and their anti-adhesive and cytotoxic properties were analysed in vitro. The most active peptide (poly RGD) was also tested in vivo to assess its modulatory activity on melanoma growth. Synthetic RGD peptides inhibit the adhesion of Ab melanoma cells to fibronectin. Poly RGD significantly inhibits primary tumour growth. There was no observed cytotoxicity of poly RGD towards Ab cells in a medium with 10% serum; however, under the same conditions, the anti-adhesive effect of poly RGD was still visible. Experiments on Jurkat cells indicated a weak cytotoxicity of poly RGD and a significant cytotoxicity of GRGDNP (the reference cytotoxic peptide), retained only under serum-free conditions. The anti-tumour effect of poly RGD observed in the Ab Bomirski melanoma model is probably due to an anti-adhesive mechanism. The proapoptotic activity of RGD peptides is dependent on the absence of serum.
10

Interleukin-2 gene therapy potentiates the antitumor effect of cytostatic agent in mice with advanced transplantable tumors

67%
Glazman-Kusnierczyk H., Pajtasz-Piasecka E., Radzikowski C.
Biotechnologia
|
1996
|
nr 4
11

Chemo-immunotherapeutical studies on Dalton's lymphoma in mice using cisplatin and ascorbic acid: synergistic antitumor effect in vivo and in vitro

67%
Sarna S., Bhola R. K.
Archivum Immunologiae et Therapiae Experimentalis
|
1993
|
tom 41
|
nr 5-6
12

Recombinant tumor necrosis factor alpha inhibits growth of methylcholanthrene-induced sarcoma and enhances natural killer activity of tumor-infiltrating lymphocytes in aging rats

67%
Ziolkowska M., Nowak J. J., Janiak M., Ryzewska A.
Archivum Immunologiae et Therapiae Experimentalis
|
1993
|
tom 41
|
nr 5-6
13

Microsporogenesis in Karwinskia parvifolia [Rhamnaceae]

67%
Hanackova Z., Pineyro-Lopez A.
Bulletin of the Polish Academy of Sciences. Biological Sciences
|
1997
|
tom 45
|
nr 2-4
14
Content available remote

Photodynamic therapy in melanoma - an update

59%
Baldea F., Filip A. G.
Journal of Physiology and Pharmacology
|
2012
|
tom 63
|
nr 2
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.