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Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Chemical composition and anti-inflammatory and anticancer effects of methanolic extract of Arum palaestinum spadices

100%

Habash B., Albarghouti G., Naseef H., Sabri I., Enaya M., Al-Rimawi F.

Acta Agrobotanica

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2024

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tom 77

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Telomerase as a therapeutic target

86%

Huminiecki L.

Acta Biochimica Polonica

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1996

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tom 43

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nr 3

Ribonucleoprotein telomerase is an enzyme that elongates telomeric DNA. In cells without detectable telomerase activity telomeres shorten with every cell generation and reaching critical length is a signal for cell death. Normal human somatic cells express undetectable, or low (bone marrow and peripheral leukocytes), telomerase activity. Reactivation of telomerase (immortalization) is probably necessary during development of a fully malignant cancer. Consequently, telomerase was proposed to be a therapeutic target for the cancer therapy. Potential results (including side-effects) of telomerase inhibition are being considered. After all, telomerase inhibition can be useful not only in the therapy, but also in cancer biology research, elucidating ageing and immortalization phenomena.

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Anti-cancer effect of betulin and its derivatives, with particular emphasis on the treatment of melanoma

72%

Cabaj J., Bak W., Wroblewska-Luczka P.

Journal of Pre-Clinical and Clinical Research

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2021

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tom 15

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nr 2

4

Exploring the potential of Inula viscosa extracts for antioxidant, antiproliferative and apoptotic effects on human liver cancer cells and a molecular docking study

72%

Kheyar-Kraouche N., Boucheffa S., Bellik Y., Farida K., Brahmi-Chendouh N.

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

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2023

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tom 104

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nr 2

5

Endotoxin exposure and lung cancer mortality by type of farming: is there a hidden dose-response relationship?

72%

Lange J. H., Mastrangelo G., Fedeli U., Fadda E., Rylander R., Lee E.

Annals of Agricultural and Environmental Medicine

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2003

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tom 10

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nr 2

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Flavonoids - food sources and health benefits

58%

Kozlowska A., Szostak-Wegierek D.

Roczniki Państwowego Zakładu Higieny

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2014

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tom 65

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nr 2

Flavonoids are a group of bioactive compounds that are extensively found in foodstuffs of plant origin. Their regular consumption is associated with reduced risk of a number of chronic diseases, including cancer, cardiovascular disease (CVD) and neurodegenerative disorders. Flavonoids are classified into subgroups based on their chemical structure: flavanones, flavones, flavonols, flavan-3-ols, anthocyanins and isoflavones. Their actions at the molecular level include antioxidant effects, as well the ability to modulate several key enzymatic pathways. The growing body of scientific evidence indicates that flavonoids play a beneficial role in disease prevention, however further clinical and epidemiological trials are greatly needed. Among dietary sources of flavonoids there are fruits, vegetables, nuts, seeds and spices. Consumption of these substances with diet appears to be safe. It seems that a diet rich in flavonoids is beneficial and its promotion is thus justifiable.

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The influence of precursors and elicitor feeding on lignans accumulation in cultures of Taxus × media roots carrying a taxadiene synthase transgene

58%

Wencel A., Syklowska-Baranek K., Lysik K., Pietrosiuk A.

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

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2015

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tom 96

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nr 1

Ograniczanie wyników

Chemical composition and anti-inflammatory and anticancer effects of methanolic extract of Arum palaestinum spadices

Telomerase as a therapeutic target

Anti-cancer effect of betulin and its derivatives, with particular emphasis on the treatment of melanoma

Exploring the potential of Inula viscosa extracts for antioxidant, antiproliferative and apoptotic effects on human liver cancer cells and a molecular docking study

Endotoxin exposure and lung cancer mortality by type of farming: is there a hidden dose-response relationship?

Flavonoids - food sources and health benefits

The influence of precursors and elicitor feeding on lignans accumulation in cultures of Taxus × media roots carrying a taxadiene synthase transgene