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Neospora and neosporosis: achievement and perspectives in diagnosis

100%

Ortega-Mora L. M., Gomez-Bautista M., Fernandez-Garcia A.

Wiadomości Parazytologiczne. Suplement

2005

tom 51

Diagnosis of bovine neosporosis: Recent advances and perspectives

100%

Ortega-Mora L. M., Fernandez-Garcia A., Gomez-Bautista M.

Acta Parasitologica

2006

tom 51

nr 1

Neospora caninum is considered a major cause of abortion in cattle. Appropriate techniques for diagnosis of bovine neosporosis, both in vivo and in aborted foetuses, have been developed in the last ten years and some of them are commercially available. For diagnosis in live animals, detection of antibodies in serum or milk has been shown to be the best option both at the herd and the individual level. These techniques are excellent tools to examine N. caninum-associated abortion problems and to adopt some basic herd-control measures. Concerning foetal diagnosis, detection of compatible lesions by histological examination and parasites by PCR in brain (as well as heart and liver) are the best choices. Diagnostic criteria to distinguish foetal infection and Neospora-associated abortion are based not only on the demonstration of the parasite in the foetus but also on the extent and severity of the lesions in the foetus, foetal age and the assessment of neosporosis at the herd level. In the near future, new tools to diagnose infection should help to detect animals with parasite reactivation by testing the immune response to stage-specific antigens and lead to the development of molecular typing methods to characterise different parasite isolates. Finally, uniform diagnostic procedures need to be established between laboratories and countries in order to standardise result interpretation. The role of National or Regional Reference Laboratories is essential in countries or regions where control programmes for the disease are being developed.

Ograniczanie wyników

1 Acta Parasitologica

1 Wiadomości Parazytologiczne. Suplement

2 Fernandez-Garcia A.

2 Gomez-Bautista M.

2 Ortega-Mora L. M.

1 2006

1 2005

Wyniki wyszukiwania

Neospora and neosporosis: achievement and perspectives in diagnosis

Diagnosis of bovine neosporosis: Recent advances and perspectives