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Molecular characterisation of Leptospira strains in Pakistan

100%

Sohail M. L., Khan M. S., Avais M., Zahoor M. Y., Khattak I., Ashraf A., Naseer O.

Journal of Veterinary Research

2016

tom 60

nr 4

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Comparative efficacy of silymarin and choline chloride (liver tonics) in preventing the effects of aflatoxin B1 in bovine calves

100%

Naseer O., Khan J. A., Khan M. S., Omer M. O., Chishti G. A., Sohail M. L., Saleem M. U.

Polish Journal of Veterinary Sciences

2016

tom 19

nr 3

Aflatoxins are secondary metabolites produced by Aspergillus spp. which are injurious to animals and humans The aim of this study was to determine the effects of aflatoxin B1 (AFB1) on Average Daily Feed Intake (ADFI), Average Daily Weight Gain (ADWG), haematological and serum biochemical responses of Bovine Calves and to determine the comparative efficacy of two different liver tonics against AFB1. Twenty seven calves were selected from herd and divided into 3 groups. All calves were fed with 1.0 mg/kg AFB1 for a period of 10 days. After that they were fed with liver tonics: Silymarin fed at a rate of 600 mg/kg and Choline chloride 500 mg/kg for 7 days. The results indicate that the ADFI and ADWG of AFB1 treated calves decreased significantly. Serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), blood urea nitrogen (BUN) and creatinine significantly increased due to AFB1. In haematology the total erythrocyte count (TEC), total leukocyte count (TLC), haemoglobin concentration (HGB), haematocrit levels (HCT), mean corpuscular haemoglobin (MCH), mean corpuscular volume (MCV) and mean corpuscular haemoglobin concentration (MCHC), lymphocyte %, neutrophil % and monocyte % significantly decreased in AFB1 treated calves after 10 days of feeding. Both liver tonics significantly (p<0.05) improved all the parameters, including ADFI, ADWG, hematologial and serum biochemical test. However, Silymarin comparatively more efficiently ameliorate the effects induced by AFB1 than choline chloride.

A systemic review of existing serological possibilities to diagnose canine osteoarthritis with a particular focus on extracellular matrix proteoglycans and protein

100%

Shahid M., Manchi G., Slunsky P., Naseer O., Fatima A., Leo B., Raila J.

Polish Journal of Veterinary Sciences

2017

tom 20

nr 1

Extra-cellular matrix (ECM) components are important and their stabilization is significant in maintaining normal healthy joint environment. In osteoarthritis (OA), ECM components are altered and indicate disease progression. The joint ECM is composed of proteoglycans (aggrecan, perlecan, inter α-trypsin inhibitor), glycoproteins (fibronectin, lubricin, COMP) and collagen types (most abundantly collagen type II) which represent structural and functional transformation during disease advancement. ECM investigation revealed significant biomarkers of OA that could be used as a diagnostic and therapeutic tool in different canine orthopedic diseases. This review deliberates our current findings of how the components of ECM change at the molecular level during disease progression in canine OA.

Ograniczanie wyników

2 Polish Journal of Veterinary Sciences

1 Journal of Veterinary Research

3 Naseer O.

2 Khan M. S.

2 Sohail M. L.

1 Ashraf A.

1 Avais M.

1 Chishti G. A.

1 Fatima A.

1 Khan J. A.

1 Khattak I.

1 Leo B.

1 Manchi G.

1 Omer M. O.

1 Raila J.

1 Saleem M. U.

1 Shahid M.

1 Slunsky P.

1 Zahoor M. Y.

1 2017

2 2016

Wyniki wyszukiwania

Molecular characterisation of Leptospira strains in Pakistan

Comparative efficacy of silymarin and choline chloride (liver tonics) in preventing the effects of aflatoxin B1 in bovine calves

A systemic review of existing serological possibilities to diagnose canine osteoarthritis with a particular focus on extracellular matrix proteoglycans and protein