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Background. Irritable Bowel Syndrome (IBS) is one of the most frequent digestive system diseases, of various medical signs. It is assumed that proper life style, including appropriate, rational diet is a factor helpful for treating such a disorder. Objective. The purpose of this paper was to assess the selected dietary habits, and to evaluate the nutritional value of daily food rations for patients with a mixed type of Irritable Bowel Syndrome. Material and Methods. The questionnaire survey involved a group of 32 women suffering from a mixed type of Irritable Bowel Syndrome (The Rome III Diagnostic Criteria were used to diagnose the disease). The control group was comprised of 32 healthy women. The methods used to assess the diet were divided into quantitative and qualitative ones. Results. The most frequent dietary mistakes among patients with IBS were associated with snacking sweets (83.0% of the subjects) and fruit (17.0% of the subjects) between the meals. A higher intake of sucrose was found amongst women with IBS, than in the case of the control group (p=0.0169). The analysis of the results demonstrated a significantly higher intake of water (derived from drinks and foods) amongst patients with IBS, than in the case of women of the control group (p=0.0267). An insufficient intake of plant proteins and polyunsaturated fatty acids was recorded in both groups. The supply of protein in general, animal protein, fat in general, saturated fatty acids and sodium, exceeded the recommended norm, both amongst women with IBS and women of the control group. Conclusions. The obtained examination results showed that there are significant dietary improprieties in the diet of women suffering from IBS. In order to eliminate these mistakes in the future, it seems justified to extend the knowledge on rational nutrition amongst patients with IBS.
This study was undertaken in order to determine the influence of chronic ethanol administration on pancreatic regeneration during acute pancreatitis (AP). Rats were pair fed with isocaloric diet containing or not ethanol. After 8 weeks of such feeding AP was induced by sc injection of caerulein (Cae). 6 h, 24 h and 5 days after first Cae dose pancreatic weight, amylase, chymotrypsin, protein, RNA, DNA contents were determined and phosphatidic acid (PA) production in isolated pancreatic acini was measured. Proliferating cells were quantified by immunochemical staining of cells incorporating bromodeoxyuridine (BrdU). Results: Pancreatic weight was significantly higher at 6 h after first Cae injection in both, ethanol fed (EF) and control groups (C), however at 24 h pancreatic weight did not differ from prior to AP induction in EF rats. Ethanol feeding (EF) did not influence significantly protein, chymotrypsin and amylase content in pancreatic tissue in groups with AP. In EF rats RNA content after 5 days of AP was higher than in control animals. Total DNA content in EF rats with AP was lower 6 h after AP induction, earlier than in control animals with AP. Immunochemistry showed higher labelling index for BrdU after 6 h, 24 h and 5 days of AP in EF rats. In contrast to this findings, in EF animals, AP induction was not able to stimulate further PA accumulation. Conclusion: We conclude that chronic ethanol feeding, while inhibiting PA accumulation in comparison to control group, does not impair pancreatic tissue regeneration during the early phase of Cae-induced AP. Stimulation of regenerative/reparative processes in EF rats during Cae-induced AP seems to be even more pronounced than in the control group.
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