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Techniki chirurgiczne stosowane przy przeszczepach rąbkowych komórek macierzystych

100%

Wylegala E., Tarnawska D., Orzechowska-Wylegala B.

Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii

2012

nr 1

Limbal stem cells (LSC) deficiency is one among the causes of corneal transparency loss. The only effective management is LSC transplantation. In available techniques the source of donor tissue containing LSC can be healthy fellow eye (CLAU, EVELAU), living-related (lr-CLAL, lr-EVELAL) or cadaveric donor (c-CLAL). From among them, the most efficient and the safest procedure is transplantation of cultured stem cells. Preoperative diagnosis and ocular surface condition determine the choice, of which procedure is the best. The surgical restoration of ocular surface is the sequence of procedures and the penetrating keratoplasty is the ultimate rehabilitative step in this process.

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A single-centre retrospective observational study of fungal keratitis in Poland with a review of findings in Europe

100%

Nowik K. E., Wylegala A., Nowik K., Wylegala E.

Annals of Agricultural and Environmental Medicine

2020

tom 27

nr 3

Decrease of RGCs number in glaucoma model vs. optic nerve transaction in rats

100%

Pietrucha-Dutczak M., Smedowski A., Wylegala E., Lewin-Kowalik J.

Acta Neurobiologiae Experimentalis

2013

tom 73

nr Suppl.1

Introduction: Transection of the optic nerve and glaucoma causes both structural and functional damage to retinal ganglion cells with subsequent vision defect or loss. This study was undertaken to compare the lost of RGCs after optic nerve transection and glaucoma model. Materials and methods: Wistar rats were divided into two groups. The first group underwent bilateral stereotactic injection of fluorescent tracer – Fluorogold (FG) into the superior colliculus to label RGCs. After one week the right optic nerve was transected. Left eye without optic nerve axotomy was established as control. In the second group intraocular pressure (right eye) was elevated by injection of polystyrene microbeads into anterior chamber (Bead model) and measured by Icare TonoLab. RGCs were labeled by FG before euthanasia. Fourteenth days following optic nerve transection and intraocular pressure elevation the total number of FG-positive RGCs was counted in seven radial sections through the optic disk. Results and conclusions: After axotomy the number of surviving cells was reduced to 20.2 % (from 2249.5 ± 127.2 – in control group to 454.7 ± 96.5 – in group after axotomy), in glaucoma model to 79.9% (from 2249.5 ± 127.2 – in control group to 1798.3 ± 118.96 – in glaucoma model).

Ograniczanie wyników

1 Acta Neurobiologiae Experimentalis

1 Annals of Agricultural and Environmental Medicine

1 Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii

3 Wylegala E.

1 Lewin-Kowalik J.

1 Nowik K.

1 Nowik K. E.

1 Orzechowska-Wylegala B.

1 Pietrucha-Dutczak M.

1 Smedowski A.

1 Tarnawska D.

1 Wylegala A.

1 2020

1 2013

1 2012

Wyniki wyszukiwania

Techniki chirurgiczne stosowane przy przeszczepach rąbkowych komórek macierzystych

A single-centre retrospective observational study of fungal keratitis in Poland with a review of findings in Europe

Decrease of RGCs number in glaucoma model vs. optic nerve transaction in rats