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The problem was envisaged in the light of 10 cases. In two of them the infection was absolutely certain, in two almost certain, being only suspected in the remaining persons. The treatment consisted in the administration of Daraprim along with sulphadiazine before and during, or only during the pregnancy. All women were delivered at term of healthy, normal babies. The children are alive have reached the age of 4-6.5 years and show a normal physical and mental development.
An investigation for toxoplasmosis was carried out with 50 women with pregnant pathology (the delivery of foetuses with developing defectiveness, spontanous abortion and mortification of pregnancy), as well as with 50 healthy women making a controlling group. In the former group positive serological and allergic reactions for ioxoplasmosis were much more frequent than in the latter. Combination. mother Rh+ father Rh - occured twice more frequently in the group with the pregnant pathology than in the controlling one. Blood analysis of the mothers with positive reactions for toxoplasmosis showed slight devi.ations in the form of somewhat increased lymphocytosis and monocytosis and sometimes somewhat increased acid-absorbing leucocyte number. Passage carried out in 23 cases on the mice chosen of suspected material and the search of parasite under the microscope did not bring positive results. The whole of investigations did not lead the formerly appointed aim, i. e. to the definition of the role of toxoplasmosis in the pregnant pathology because of the imperfection of diagnostic methods. They make however grounds to the conclusion that toxoplasmosis in probably quite frequent disease here and in our present conditions a whole set of factors must decide about its diagnosis. These factors are leaded by a characteristic clinical picture and positive serological and allergic reactions for toxoplasmosis.
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