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1

Sposób żywienia a ryzyko wystąpienia depresji u osób dorosłych

100%
Szmidt M., Granda D., Kaluza J.
Żywienie Człowieka i Metabolizm
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2019
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tom 46
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nr 02
2

Poszukiwanie skutecznych i bezpiecznych antymykotyków wśród halogenowych pochodnych kwasów karboksylowych do zastosowania w terapii kryptokokozy

100%
Dylag M., Szmidt M., Salwinska W., Kalinowska K.
Postępy Mikrobiologii. Suplement
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2019
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tom 58
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nr 1
3
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

The influence of nanodiamond particles on rat health status

100%
Szmidt M., Niemiec T., Sawosz-Chwalibog E., Mitura K.
Annals of Warsaw University of Life Sciences - SGGW. Animal Science
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2013
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tom 52
The objective of the present investigation was to evaluate the effect of nanodiamond (ND) particles on rats health status. 1 mg/kg b.w. of nanodiamond particles was administrated intravenously and intraperitoneum. The presence of an adverse impact was examined. The results show significant changes in biochemical (glucose and total protein level decrease) and hematological (elevated platelets count) parameters, only in case of intravenous injection.
4

The effect of dietary L-ascorbic acid megadoses on the morphology of the lens in rats

100%
Niemiec T., Ostaszewska T., Sawosz E., Szmidt M.
Journal of Animal and Feed Sciences. Supplement
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2006
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tom 15
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nr 1
5

Zmienność parametrów wydzieliny dróg rodnych w przebiegu cyklu rujowego bydła ze szczególnym uwzględnieniem okresu płodnego

100%
Urbanska K., Szmidt M., Borecki M., Sysa P.
Życie Weterynaryjne
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2011
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tom 86
|
nr 02
6
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Glejak wielopostaciowy u psów

88%
Urbanska K., Sokolowska J., Szmidt M., Grodzik M., Sysa P.
Życie Weterynaryjne
|
2011
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tom 86
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nr 10
7
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
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Carbon synthetized by RF PACVD method enhances the activity of antioxidants

88%
Niemiec T., Szmidt M., Kruk-Roszkowska A., Sawosz-Chwalibog E., Mitura K.
Annals of Warsaw University of Life Sciences - SGGW. Animal Science
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2013
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tom 52
The aim of the presented study was to evaluate the reductive activity of antioxidants in the presence of carbon manufactured by Radio Frequency Plasma Activated Chemical Vapor Deposition method (RF PACVD). 2,2-diphenyl-1-picrylhydrazyl (DPPH) method was employed to estimate antioxidants reductive potential. Based on the experimental results, the antioxidant activity of carbon colloid was not confirmed. Nevertheless the reductive activity of antioxidants measured in time manner, in the presence of carbon, was significantly elevated comparing to the antioxidants alone. The presented results suggest that the surface of carbon syn-thetized by RF PACVD method suspended in water, creates more friendly reductive environment for antioxidants with hydroxyl groups (ascorbic acid - AA and butylated hydroxyanisole - BHA) then with sulfhydryl groups (glutathione - GSH).
8

Analysis of Velvet Scoter Melanitta fusca heart structures in ecological aspect

76%
Bartyzel B. J., Szmidt M., Barszcz K., Dzierzecka M., Charuta A., Wasowicz M., Kobryn H.
Electronic Journal of Polish Agricultural Universities. Series Veterinary Medicine
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2008
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tom 11
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nr 2
9

Morphology of human glioblastoma model cultured in ovo

76%
Szmidt M., Urbanska K., Grodzik M., Orlowski P., Sawosz E., Wierzbicki M., Sysa P.
Bulletin of the Veterinary Institute in Puławy
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2012
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tom 56
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nr 2
The aim of this study was the morphological characterisation of glioblastoma multiforme tumour grown in ovo. Tumour cells (U-87 MG) were implanted on the chorioallantoic membrane of chicken egg. The structural features of cultured tumours resembled the spontaneous glioblastoma multiforme; however, the differences were also indicated. Our results confirm applicability of in ovo culture in tumour genesis studies. The described novel model may be profoundly helpful for the future research on molecular mechanisms of tumour growth inhibition.
10

Od komórki do produkcji zwierzęcej - badania i perspektywy zastosowania nanocząstek srebra

76%
Niemiec T., Szmidt M., Sawosz E., Grodzik M., Lozicki A., Struzynski W.
Przegląd Hodowlany
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2013
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tom 81
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nr 6
11

Can silver nanoparticles affect the mineral content, structure and mechanical properties of chicken embryo bones?

76%
Sikorska J., Szmidt M., Sawosz E., Niemiec T., Grodzik M., Chwalibog A.
Journal of Animal and Feed Sciences
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2010
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tom 19
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nr 2
286-291
Biomedical application of silver nanoparticles has recently gained much attention. In this study, we investigated whether hydrocolloids of silver nanoparticles (nano-Ag) are deposited in chicken bones during embryogenesis and to what extent they can affect biochemical characteristics, mineral content, structure, and mechanical properties of bones. Hydrocolloids (0.3 ml), containing 50 ppm of nano-Ag, were injected in ovo prior to incubation of eggs. After 20 days of incubation, blood and thigh bones were isolated and analysed. Nano-Ag was deposited in embryo thigh bones, but did not affect the structure or mechanical properties of the bone. There was no effect of nano-Ag on the selected biochemical indices, but there was a tendency towards increasing mineral content, indicating that nanoparticles may influence bone mineralization. Considering that nano-Ag is absorbed by the embryo skeleton without affecting bone properties, these particles might be a good candidate for carriers of micronutrients or drugs into bones.
12
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Pathomorphological changes in the small intestine and liver of the European beaver (Castor fiber L. 1758): a case study

64%
Niemiec T., Sikorowski K., Struzynski W., Pasko S., Bartyzel B. J., Szmidt M., Balcerak M., Januta G., Bielecki W., Koczon P.
Annals of Warsaw University of Life Sciences - SGGW. Animal Science
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2016
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tom 55[2]
Pathomorphological Changesin the Small Intestine and Liver of the European Beaver (Castor fiber L. 1758): a case study.The aim of thestudy was to examine and describe the morphology and patomorphology of small intestine and liver of European beaver (Castor fiber). In natural environment beavers are in constant contact with various both internal and external parasites. Histological analysis revealed the pathological changes within the digestive track and liver indicating long-term inflammation. It was hypothesized that the observed inflammation was caused by the parasites not related to beavers so far.
13

Influence of hydrocolloids of Ag, Au, and Ag-Cu alloy nanoparticles on the inflammatory state at transcriptional level

64%
Sawosz E., Grodzik M., Lisowski P., Zwierzchowski L., Niemiec T., Zielinska M., Szmidt M., Chwalibog A.
Bulletin of the Veterinary Institute in Puławy
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2010
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tom 54
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nr 1
81-85
The objective of this investigation was to evaluate the pro- or anti-inflammatory properties of nanoparticles of Ag, Au, and Ag/Cu alloy by examining the expression of NF-κB mRNA. The experiment was performed in ovo, on the chicken embryos' model. The nanoparticles had no effect on embryos' survival; the embryos from all groups were properly developed, without any abnormalities. Contrary to Ag and Au, nanoparticles of Ag/Cu increased NF-κB mRNA expression in embryo liver, indicating a proinflammatory effect. After treatment with LPS there was a significant decrease in NF-κB mRNA expression in the liver of embryos treated with Ag, compared to the placebo, Au, and Ag/Cu groups, indicating that Ag nanoparticles act as a potential anti-inflammatory factor. The results indicate the lack of influence of Ag and Au nanoparticles on NF-κB mRNA expression in chicken embryo liver. Contrary to Ag and Au, nanoparticles of Ag/Cu alloy may be considered as a pro-inflammatory factor. Nanoparticles of Ag, but not Au and Ag/Cu, can prevent over-expression of NF-κB mRNA after LPS stimulation.
14
Content available remote

Alpha-ketoglutarate stabilizes redox homeostasis and improves arterial elasticity in aged mice

64%
Niemiec T., Sikorska J., Harrison A., Szmidt M., Sawosz E., Wirth-Dzieciolowska E., Wilczak J., Pierzynowski S.
Journal of Physiology and Pharmacology
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2011
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tom 62
|
nr 1
The objective of this study was to evaluate the effect of -ketoglutarate on redox state parameters and arterial elasticity in elderly mice. Mice in the control group were fed with standard diet, while the experimental animals received the diet supplemented either with calcium (Ca-AKG) or sodium salt of -ketoglutarate (Na-AKG). The experimental animals were divided into 4 groups with 10 individuals in each: control I (12 months old), control II (2 months old), experimental group I fed with Ca-AKG (12 months old) and experimental group II fed with Na-AKG (12 months old). Mice treated with Ca-AKG as well as the control II animals demonstrated significantly higher level of total antioxidant status (TAS), comparing to the control I animals and those treated with Ca-AKG. Thiobarbituric acid reactive substances (TBARS) level in blood plasma was found significantly lower in young and Ca-AKG treated mice. TBARS liver concentration was significantly different in each examined group. The study also demonstrates the decrease in TBARS level in Ca-AKG treated animals. Treatment with Na-AKG significantly increased glutathione peroxidase activity and decreased the activity of superoxide dismutase. The presented results suggest that Ca-AKG protects the organism against the free radicals related elderly processes. The study presents also the effect of Ca-AKG treatment on arterial elastic characteristics in elderly mice. The beneficial effect of Ca-AKG on ageing organisms was confirmed via redox state stabilization and blood vessel elasticity improvement.
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