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DNA polymorphism of the alphaA-globin gene in domestic pigeon

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Dybus A., Chang M.-H., Cheng Y.-H., Szatkowska I.

Animal Science Papers and Reports

2008

tom 26

nr 3

The study aimed at identifying the polymorphism of domestic pigeon αA-globin gene which can be a potential homing marker in selection of racing pigeons. A total of 329 domestic pigeons were genotyped using the polymerase chain reaction-restriction fragment length polymorphism (PCRRFLP)method. The PCR products were digested with 17 restriction endonucleases. One RFLP – detected with HphI – was found in intron 1 and represented a C/T mutation. The second RFLP – detected with BseLI – was a point mutation in the 3’UTR region of the gene (C/T mutation). The polymorphism in the 3’UTR region of the pigeon αA-globin gene can potentially affect the stability of mRNA and modify the gene expression. The mechanisms of haemoglobin function reflecting variants of the αA-globin gene remain unknown.

Ograniczanie wyników

1 Animal Science Papers and Reports

1 Chang M.-H.

1 Cheng Y.-H.

1 Dybus A.

1 Szatkowska I.

1 2008

Wyniki wyszukiwania

DNA polymorphism of the alphaA-globin gene in domestic pigeon