The current study assessed trace metal contamination in sediments using different types of indices. Six heavy metals such as Cu, Zn, Mg, Fe, Mn, and Ca were investigated in the sediments of the Farah Abad region in Iran. The metals concentration was found in the range of 15, 16, 59, 770, 3.2, and 14.5 mg/kg for Cu, Zn, Mn, Fe, Mg, and Ca, respectively. The enrichment factor was lower than unity, indicating the absence of anthropogenic influence. The contamination factor and geo-accumulation indices for Cu, Zn, Mn, Mg, and Ca were <1 and <0, respectively, indicating no pollution at all from the selected metals, whereas CF and Igeo values for Fe were significantly greater than 5, suggesting a high enrichment from anthropogenic sources. The potential ecological risk index for Cu and Zn showed a value of 2.376, indicating low ecological risk to the selected sites from the accumulation of trace metals.