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1

Synovial membrane asks for independence

100%
Moskalewski S., Osiecka-Iwan A., Jankowska-Steifer E., Hyc A.
Folia Morphologica
|
2014
|
tom 73
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nr 4
Synovial membrane is traditionally considered as a part of the joint capsule. It, however, differs from fibrous part of the capsule in development, structure, function, vascularisation, innervation and involvement in pathological processes. Moreover, in some areas, it even does not contact with the fibrous capsule. Thus, it appears that the synovial membrane should be considered as an independent organ and not as the lining of the joint capsule. (Folia Morphol 2014; 73, 4: 395–398)
2

Growth factors in the initial stage of bone formation, analysis of their expression in chondrocytes from epiphyseal cartilage of rat costochondral junction

100%
Hyc A., Moskalewski S., Osiecka-Iwan A.
Folia Histochemica et Cytobiologica
|
2021
|
tom 59
|
nr 3
3

Influence of IGF-1, TGF-beta1 and bFGF on gene expression in cruciate ligament and dermal fibroblasts

100%
Hyc A., Zeberkiewicz M., Osiecka-Iwan A.
Folia Biologica
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2018
|
tom 66
|
nr 2
4

Formation of synovial joints and articular cartilage

100%
Moskalewski S., Hyc A., Jankowska-Steifer E., Osiecka-Iwan A.
Folia Morphologica
|
2013
|
tom 72
|
nr 3
Chondrocytes differentiate from mesenchymal progenitors and produce templates (anlagen) for the developing bones. Chondrocyte differentiation is controlled by Sox transcription factors. Templates for the neighbour bones are subsequently separated by conversion of differentiated chondrocytes into non-chondrogenic cells and emergence of interzone in which joints cavitation occurs. A central role in initiating synovial joint formation plays Wnt-14/beta-catenin signalling pathway. Moreover, bone morphogenetic proteins and growth and differentiation factors are expressed at the site of joint formation. Joint cavitation is associated with increased hyaluronic acid synthesis. Hyaluronic acid facilitates tissue separation and creation of a functional joint cavity. According to the traditional view articular cartilage represents part of cartilage anlage that is not replaced by bone through endochondral ossification. Recent studies indicate, however, that peri-joint mesenchymal cells take part in interzone formation and that these interzone cells subsequently differentiate into articular chondrocytes and synovial cells. Thus, anlage chondrocytes have a transient character and disappear after cessation of growth plate function while articular chondrocytes have stable and permanent phenotype and function throughout life. (Folia Morphol 2013; 72, 3: 181–187)
5

Influence of cartilage interstitial fluid on gene expression in dermal fibroblasts

100%
Hyc A., Moskalewski S., Stankevic D., Osiecka-Iwan A.
Folia Biologica
|
2017
|
tom 65
|
nr 1
6

Influence of IGF1, TGFbeta1, bFGF and G-CSF/M-CSF on the mRNA levels of selected matrix proteins, cytokines, metalloproteinase 3 and TIMP1 in rat synovial membrane cells

100%
Osiecka-Iwan A., Moskalewski S., Hyc A.
Folia Histochemica et Cytobiologica
|
2016
|
tom 54
|
nr 3
7

Formation of lamellar bone on the surface of woven bone is not prevented by BAPN

100%
Moskalewski S., Osiecka-Iwan A., Mankowska E.
Folia Histochemica et Cytobiologica
|
1996
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tom 34
|
nr 2
8

Cartilage formed by syngeneic rat chondrocytes in joint surface defects is rejected in animals sensitized with allogeneic chondrocytes: involvement of the synovial lining

100%
Moskalewski S., Osiecka-Iwan A., Hyc A., Niderla J.
Archivum Immunologiae et Therapiae Experimentalis
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2005
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tom 53
|
nr 2
9

Preparation of rat synovial membrane for studies of cytokine secretion

100%
Hyc A., Osiecka-Iwan A., Dziunycz P., Moskalewski S.
Folia Histochemica et Cytobiologica
|
2007
|
tom 45
|
nr 1
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