The objective of the studies was to determine the dynamics of certain parameters of nonspecific cellular and humoral immunity in piglets in the post-natal period. The parameters of immune responses were determined in blood samples of 7 randomly chosen piglets before feeding them their first doses of colostrum, 48 h after colostrum feeding and at the age of 7, 14, 21 and 35 days of life. The following parameters were examined: the NBT, phagocytic index, test of intracellular killing, level of total protein and γ-globulin complex, lysozyme activity and IgG concentration. It was found that the nonspecific mechanisms of cellular and humoral immunity increased along with the age of piglets. Moreover, the serum IgG level diminished quickly from 30 g/l at the age of 48 h to 3,7 g/l at the age 35 days. The results of examination indicate that piglets are the most sensitive to diseases between their first 14 to 35 days of life.
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