Yields of herbs of both compared species were significantly higher in the second year (St. John's-wort by 47%, and goldenrod by 20%). The share of the most valuable parts (leaves and flowers) in the raw material was similar in the first and second year (St. John's-wort: 68% and 69%, goldenrod: 73% and 68%, respectively). As far as the contents of biologically active compounds are concerned, the raw material obtained in the second year was more valuable: hypericine in St John's-wort increased by 0.2% and leiocarposide in goldenrod by 0.15% (flavonoids were at the same level).