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The purpose of the study was to evaluate the efficiency of 50% Nifursol for the control of trichomonosis in pigeons. The experiment was carried out under laboratory conditions on 6 groups of racing pigeons (24 pigeons in each group), divided into 3 sub-groups (isolated from each other) each with the same number of birds. Before the experiment was started, the health of the birds was examined. The pigeons selected for the study were free from Salmonella, Chlamydophila and Campylobacter. Before the pigeons were divided into the groups, they had been infected with a 48-hour culture of Trichomonas gallinae. The efficiency of the infection was determined by conducting parasitological examination 7 days after infection. Crop swabs were collected for microscope preparations and observations. The intensity of invasion was indicated by the number of pluses (+), depending on the number of Trichomonas gallinae in the visual area. Group I consisted of non-treated, infected birds. The birds in Groups II, III, IV and V received 50% Nifursol at doses of 150, 300, 600 and 1200 mg/kg of feed, respectively. Group VI also received 20% Metronidazol (reference drug) at a dose of 3g/l of water. The efficiency of the drugs used in the study was evaluated with regard to clinical observations and parasitological examinations conducted after 1, 2, 3, 4 and 6 weeks from the day the birds were found to be infected with Trichomonas gallinae. When the drug administration was accomplished, 10 pigeons from each group were randomly selected for haematological and biochemical examinations of blood samples. The results showed a high efficiency of 50% Nifursol administered at the doses of 600 and 1200 mg/kg of feed. The results obtained in our experiment also show that a dose of 600 mg/kg of feed administered to pigeons for a 4-week period is efficient for the treatment of Trichomonas gallinae invasion. The results obtained in clinical, biochemical and hematological studies prove that even long-term (up to 6 weeks) administration of 50% Nifursol at a dose not exceeding 600 mg/kg of feed is safe to the birds and will not deteriorate the physiological functions of inner organs in pigeons.
The research was done in the dermatological laboratory of Bytom Hospital No 2 in the years 1979-1983. 31 842 women were examined at the age 16 to 82. Samples were taken from urethra and neck of the uterus with sterylized oese. Both direct slides in 0,9 % NaCl solution and permanent slides were made. The latter were dyed by means of Gram's method in order to establish identity of C. albicans and by means of Giemsa's method to identity T. vaginalis. During 5 years the cases of trichomonadosis and candidosis recorded in the years of 1982 and 1983 were the most numerous. Seasonal fluctuation of trichomonadosis in 1980 and 1983 years and of candidosis in 1970, 1980, 1983 are also presented.
By the modification of chemical structure of some drugs the series of ether compounds with potential anti-trichomoniasis and anti-fungial action were received.
The authors showed the frequency of occurrence of trichomonadosis and candidosis in 31 842 women living in the Upper Silesia territory. The most extensive invasion of T. vaginalis and C. albicans was found in autumn, and in women 24-34 years old.
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