Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: translation reinitiation

Sortuj według:

Ogranicz wyniki do:

The optimal eukaryotic signal for translation initiation from non-aug codons, present upstream of bacteriophage lambda P cistron, is inactive in Escherichia coli

100%

Wrobel B., Slominski B., Wegrzyn G.

Cellular and Molecular Biology Letters

2003

tom 08

nr 2

Expression of the replication genes of bacteriophage λ, O and P, is believed to be translationally coupled. However, it was previously noted that, under conditions of amino acid starvation, when O is not synthesized, P continues to be expressed at a relatively high level. The results presented in this report, contrary to the previously presented hypothesis, suggest that an AGACUGGAU sequence (an optimal context for translation initiation from non-AUG codons in eukaryotes, and present upstream the P cistron) is inactive in Escherichia coli. Comparative sequence analysis confirms that such a signal is unlikely to be important for P synthesis. Instead, a weak Shine-Dalgarno sequence may be present upstream the P cistron, and be active in the absence of O gene expression.

Ograniczanie wyników

1 Cellular and Molecular Biology Letters

1 Slominski B.

1 Wegrzyn G.

1 Wrobel B.

1 2003

Wyniki wyszukiwania

The optimal eukaryotic signal for translation initiation from non-aug codons, present upstream of bacteriophage lambda P cistron, is inactive in Escherichia coli