A method for assessing of crop production systems in crop rotation, from the view point of profitability, yield stability and environmental sustainability to agrochemical pollution, was presented. Four crop rotations were compared: A - sugar beet, oats, winter wheat, winter barley; B - sugar beet, potatoe, winter wheat, spring barley; C - sugar beet, winter wheat, maize, maize; D - sugar beet, spring wheat, sugar beet, winter wheat. Also five systems of crop production, different in chemical application, were considered: 1 - small risk, ca. 20% more chemical treatments (fertilizers, pesticides) than in 2; 2 - integrated production, sustainable fertilization and plant protection; 3 - slightly reduced chemical treatments (fertilizers, pesticides), ca. 20% less than in 2 (like in drinking water protection region); 4-heavily reduced chemical treatments, ca. 50% less than in 2; 5 - without any synthetic chemicals like in ecological farming. It was found that from among twenty production combinations, in seven no desired profitability, in nine no desired yield stability, and in eight no required environmental sustainability were achieved. The presented method of evaluation is easy to use in practice, takes into account the advance in production system improvement and it is open for new information changing thresholds of evaluation.