The experiment was carried out on 34 calves from birth (day 0) to 18 days of age. ACTH secretion stimulation was performed on 18 calves using arginino-vasopressine AVP Sigma, given intramuscular at a dose of 0.1 IU/kg of body weight. ACTH secretion inhibition was conducted on 16 calves by means of dexamethasone Dexaven Polfa, administered intravenously at a dose of 50 µg/kg of body weight. The hormones were administered on 0, 3, 7, 12 and 18 days after birth. Blood samples were collected between 8.00 to 8.30 a.m. The levels of ACTH and cortisol were determined in sera of the animals. The hypophysis-adrenal cortex system in calves was found to be capable of a full feedback reaction from the second week of life.
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